p53 isoforms Δ133p53 and p53β are endogenous regulators of replicative cellular senescence
暂无分享,去创建一个
Borivoj Vojtesek | Curtis C. Harris | Izumi Horikawa | Jane J. Sohn | Ewy A. Mathe | David P. Lane | Kensuke Kumamoto | A. Schetter | E. Bowman | K. Kumamoto | C. Harris | D. Lane | B. Vojtesek | J. Bourdon | E. Mathé | I. Horikawa | Sharon R. Pine | Jean-Christophe Bourdon | Kaori Fujita | Abdul M. Mondal | Giang H. Nguyen | Elise D. Bowman | Aaron J. Schetter | Helen Ji | K. Fujita | A. Mondal | G. Nguyen | J. Sohn | H. Ji | B. Vojtěšek
[1] Jonathan Melamed,et al. Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence , 2008, Cell.
[2] Izumi Horikawa,et al. Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence. , 2008, Cancer research.
[3] Naoto Tsuchiya,et al. Tumor-suppressive miR-34a induces senescence-like growth arrest through modulation of the E2F pathway in human colon cancer cells , 2007, Proceedings of the National Academy of Sciences.
[4] C. Harris,et al. Metabolism of 1,2-dimethylhydrazine by cultured human colon. , 1980, Carcinogenesis.
[5] Michael R. Green,et al. Oncogenic BRAF Induces Senescence and Apoptosis through Pathways Mediated by the Secreted Protein IGFBP7 , 2008, Cell.
[6] M. Yamakuchi,et al. miR-34a repression of SIRT1 regulates apoptosis , 2008, Proceedings of the National Academy of Sciences.
[7] L. Lim,et al. A microRNA component of the p53 tumour suppressor network , 2007, Nature.
[8] J. Potter,et al. Telomere Length in the Colon Declines with Age: a Relation to Colorectal Cancer? , 2006, Cancer Epidemiology Biomarkers & Prevention.
[9] Moshe Oren,et al. Transcriptional activation of miR-34a contributes to p53-mediated apoptosis. , 2007, Molecular cell.
[10] Bas van Steensel,et al. TRF2 Protects Human Telomeres from End-to-End Fusions , 1998, Cell.
[11] R. Bernards,et al. Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence , 2006, Nature Cell Biology.
[12] J Khan,et al. The MYCN oncogene is a direct target of miR-34a , 2008, Oncogene.
[13] Dimitris Kletsas,et al. Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints , 2006, Nature.
[14] Zhenhai Zhang,et al. p53 isoform delta113p53 is a p53 target gene that antagonizes p53 apoptotic activity via BclxL activation in zebrafish. , 2009, Genes & development.
[15] T. Fojo,et al. p53 Inhibits Hypoxia-inducible Factor-stimulated Transcription* , 1998, The Journal of Biological Chemistry.
[16] M. Blasco,et al. Cellular Senescence in Cancer and Aging , 2007, Cell.
[17] John M Sedivy,et al. Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a). , 2004, Molecular cell.
[18] Ying Feng,et al. Supplemental Data P53-mediated Activation of Mirna34 Candidate Tumor-suppressor Genes , 2022 .
[19] D. Peeper,et al. Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network , 2008, Cell.
[20] David P Lane,et al. p53 isoforms can regulate p53 transcriptional activity. , 2005, Genes & development.
[21] J. Shay,et al. BLM helicase‐dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination , 2003, The EMBO journal.
[22] George A Calin,et al. MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. , 2008, JAMA.
[23] W. El-Deiry,et al. p53 downstream target genes and tumor suppression: a classical view in evolution , 2007, Cell Death and Differentiation.
[24] N. Sharpless,et al. Ink4a/Arf expression is a biomarker of aging. , 2004, The Journal of clinical investigation.
[25] E. Furth,et al. p16(INK4a) expression begins early in human colon neoplasia and correlates inversely with markers of cell proliferation. , 2000, Gastroenterology.
[26] Robin C. Allshire,et al. Telomere reduction in human colorectal carcinoma and with ageing , 1990, Nature.
[27] Izumi Horikawa,et al. Functional diversity of human protection of telomeres 1 isoforms in telomere protection and cellular senescence. , 2007, Cancer research.
[28] Y. Furukawa,et al. CDC20, a potential cancer therapeutic target, is negatively regulated by p53 , 2008, Oncogene.
[29] Wenyi Wei,et al. Bypass of senescence after disruption of p21CIP1/WAF1 gene in normal diploid human fibroblasts. , 1997, Science.
[30] V. Rotter,et al. Amyloid-β precursor-like protein APLP1 is a novel p53 transcriptional target gene that augments neuroblastoma cell death upon genotoxic stress , 2007, Oncogene.
[31] M. Barbacid,et al. Tumour biology: Senescence in premalignant tumours , 2005, Nature.
[32] C. Harley,et al. The telomere hypothesis of cellular aging , 1992, Experimental Gerontology.
[33] Michael A. Beer,et al. Transactivation of miR-34a by p53 broadly influences gene expression and promotes apoptosis. , 2007, Molecular cell.
[34] T. Hupp,et al. Posttranslational Modifications of p53 in Replicative Senescence Overlapping but Distinct from Those Induced by DNA Damage , 2000, Molecular and Cellular Biology.
[35] G. Wahl,et al. Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles , 1992, Cell.
[36] T. Roberts,et al. Surveillance mechanism linking Bub1 loss to the p53 pathway , 2007, Proceedings of the National Academy of Sciences.
[37] J. Campisi,et al. Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation , 2004, Journal of Cell Science.
[38] S. Lowe,et al. Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a , 1997, Cell.
[39] Jiri Bartek,et al. An Oncogene-Induced DNA Damage Model for Cancer Development , 2008, Science.