Gene-by-age effects on BMI from Birth to Adulthood: The Fels Longitudinal Study

Genome wide association studies have shown 32 loci to influence BMI in European‐American adults but replication in other studies is inconsistent and may be attributed to gene‐by‐age effects. The aims of this study were to determine if the influence of the summed risk score of these 32 loci (GRS) on BMI differed across age from birth to 40 years, and to determine if additive genetic effects other than those in the GRS differed by age.

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