Enzymes and auxiliary factors for GPI lipid anchor biosynthesis and post-translational transfer to proteins.
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Sebastian Maurer-Stroh | Birgit Eisenhaber | Frank Eisenhaber | Maria Novatchkova | Georg Schneider | F. Eisenhaber | S. Maurer-Stroh | Georg Schneider | B. Eisenhaber | M. Novatchkova | G. Schneider | Georg Schneider
[1] Y. Maeda,et al. Structural Requirements for the Recruitment of Gaa1 into a Functional Glycosylphosphatidylinositol Transamidase Complex* , 2002, The Journal of Biological Chemistry.
[2] P. Seeberger,et al. Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria , 2002, Nature.
[3] Eugene V Koonin,et al. Classification of the caspase–hemoglobinase fold: Detection of new families and implications for the origin of the eukaryotic separins , 2002, Proteins.
[4] R. Schwarz,et al. The GPI1 homologue from Plasmodium falciparum complements a Saccharomyces cerevisiae GPI1 anchoring mutant. , 2002, Molecular and biochemical parasitology.
[5] Michael Y. Galperin,et al. Conserved core structure and active site residues in alkaline phosphatase superfamily enzymes , 2001, Proteins.
[6] R. Huber,et al. Crystal structure of the tricorn protease reveals a protein disassembly line , 2001, Nature.
[7] P. Orlean,et al. Ynl038wp (Gpi15p) is the Saccharomyces cerevisiae homologue of human Pig‐Hp and participates in the first step in glycosylphosphatidylinositol assembly , 2001, Yeast.
[8] A. van Dorsselaer,et al. The GPI transamidase complex of Saccharomyces cerevisiae contains Gaa1p, Gpi8p, and Gpi16p. , 2001, Molecular biology of the cell.
[9] G. Cross,et al. Purification, cloning and characterization of a GPI inositol deacylase from Trypanosoma brucei , 2001, The EMBO journal.
[10] N. Inoue,et al. PIG‐S and PIG‐T, essential for GPI anchor attachment to proteins, form a complex with GAA1 and GPI8 , 2001, The EMBO journal.
[11] P. Orlean,et al. The Essential Smp3 Protein Is Required for Addition of the Side-branching Fourth Mannose during Assembly of Yeast Glycosylphosphatidylinositols* , 2001, The Journal of Biological Chemistry.
[12] Terry K. Smith,et al. Specificity of GlcNAc‐PI de‐N‐acetylase of GPI biosynthesis and synthesis of parasite‐specific suicide substrate inhibitors , 2001, The EMBO journal.
[13] D. Higgs,et al. The human GPI1 gene is required for efficient glycosylphosphatidylinositol biosynthesis. , 2001, Gene.
[14] E. Gilboa,et al. Efficient retrovirus-mediated PIG-A gene transfer and stable restoration of GPI-anchored protein expression in cells with the PNH phenotype. , 2001, Blood.
[15] M. Hattori,et al. Molecular cloning and characterization of a gene expressed in mouse developing tongue, mDscr5 gene, a homolog of human DSCR5 (Down syndrome Critical Region gene 5) , 2001, Mammalian Genome.
[16] T. Kuno,et al. Its8, a Fission Yeast Homolog of Mcd4 and Pig-n, Is Involved in GPI Anchor Synthesis and Shares an Essential Function with Calcineurin in Cytokinesis* , 2001, The Journal of Biological Chemistry.
[17] A. Menon,et al. Endoplasmic reticulum proteins involved in glycosylphosphatidylinositol-anchor attachment: photocrosslinking studies in a cell-free system. , 2001, European journal of biochemistry.
[18] A. Krogh,et al. Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. , 2001, Journal of molecular biology.
[19] R. Watanabe,et al. PIG‐M transfers the first mannose to glycosylphosphatidylinositol on the lumenal side of the ER , 2001, The EMBO journal.
[20] G. Newton,et al. N-Acetyl-1-d-myo-Inosityl-2-Amino-2-Deoxy-α-d-Glucopyranoside Deacetylase (MshB) Is a Key Enzyme in Mycothiol Biosynthesis , 2000, Journal of bacteriology.
[21] T. Kinoshita,et al. Dissecting and manipulating the pathway for glycosylphos-phatidylinositol-anchor biosynthesis. , 2000, Current opinion in chemical biology.
[22] R. Campbell,et al. The structure of UDP-N-acetylglucosamine 2-epimerase reveals homology to phosphoglycosyl transferases. , 2000, Biochemistry.
[23] G. H. Coombs,et al. Soluble GPI8 restores glycosylphosphatidylinositol anchoring in a trypanosome cell-free system depleted of lumenal endoplasmic reticulum proteins. , 2000, The Biochemical journal.
[24] A. Crossman,et al. Parasite-specific inhibition of the glycosylphosphatidylinositol biosynthetic pathway by stereoisomeric substrate analogues. , 2000, Biochemistry.
[25] P. Orlean,et al. Photoaffinity labelling with P3-(4-azidoanilido)uridine 5'-triphosphate identifies gpi3p as the UDP-GlcNAc-binding subunit of the enzyme that catalyses formation of GlcNAc-phosphatidylinositol, the first glycolipid intermediate in glycosylphosphatidylinositol synthesis. , 2000, The Biochemical journal.
[26] R. Schwarz,et al. Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[27] V. Fülöp,et al. Catalysis of serine oligopeptidases is controlled by a gating filter mechanism , 2000, EMBO reports.
[28] K. Kangawa,et al. Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG‐P and is regulated by DPM2 , 2000, The EMBO journal.
[29] A. Conzelmann,et al. YLL031c Belongs to a Novel Family of Membrane Proteins Involved in the Transfer of Ethanolaminephosphate onto the Core Structure of Glycosylphosphatidylinositol Anchors in Yeast* , 2000, The Journal of Biological Chemistry.
[30] R. Mott,et al. Accurate formula for P-values of gapped local sequence and profile alignments. , 2000, Journal of molecular biology.
[31] R. Watanabe,et al. Requirement of PIG-F and PIG-O for Transferring Phosphoethanolamine to the Third Mannose in Glycosylphosphatidylinositol* , 2000, The Journal of Biological Chemistry.
[32] P Bork,et al. Automated annotation of GPI anchor sites: case study C. elegans. , 2000, Trends in biochemical sciences.
[33] M. Sternberg,et al. Enhanced genome annotation using structural profiles in the program 3D-PSSM. , 2000, Journal of molecular biology.
[34] K. Kangawa,et al. Human dolichol‐phosphate‐mannose synthase consists of three subunits, DPM1, DPM2 and DPM3 , 2000, The EMBO journal.
[35] C. Hutchinson,et al. Thioesterases and the premature termination of polyketide chain elongation in rifamycin B biosynthesis by Amycolatopsis mediterranei S699. , 2000, The Journal of antibiotics.
[36] N. Shimizu,et al. Isolation of two novel genes, DSCR5 and DSCR6, from Down syndrome critical region on human chromosome 21q22.2. , 2000, Biochemical and biophysical research communications.
[37] C. Ponting,et al. Homology-based method for identification of protein repeats using statistical significance estimates. , 2000, Journal of molecular biology.
[38] P. Orlean,et al. Glycosylphosphatidylinositol biosynthesis defects in Gpi11p- and Gpi13p-deficient yeast suggest a branched pathway and implicate gpi13p in phosphoethanolamine transfer to the third mannose. , 2000, Molecular biology of the cell.
[39] H. Riezman,et al. Gaa1p and gpi8p are components of a glycosylphosphatidylinositol (GPI) transamidase that mediates attachment of GPI to proteins. , 2000, Molecular biology of the cell.
[40] Mark C. Field,et al. Acylation-dependent Protein Export inLeishmania * , 2000, The Journal of Biological Chemistry.
[41] G. H. Coombs,et al. Leishmania mexicana mutants lacking glycosylphosphatidylinositol (GPI):protein transamidase provide insights into the biosynthesis and functions of GPI-anchored proteins. , 2000, Molecular biology of the cell.
[42] I. Imhof,et al. Active site determination of Gpi8p, a caspase-related enzyme required for glycosylphosphatidylinositol anchor addition to proteins. , 2000, Biochemistry.
[43] H. Riezman,et al. Pig-n, a Mammalian Homologue of Yeast Mcd4p, Is Involved in Transferring Phosphoethanolamine to the First Mannose of the Glycosylphosphatidylinositol* , 1999, The Journal of Biological Chemistry.
[44] David T. Jones,et al. β Propellers: structural rigidity and functional diversity , 1999 .
[45] Alejandro A. Schäffer,et al. IMPALA: matching a protein sequence against a collection of PSI-BLAST-constructed position-specific score matrices , 1999, Bioinform..
[46] Terry K. Smith,et al. Selective inhibitors of the glycosylphosphatidylinositol biosynthetic pathway of Trypanosoma brucei , 1999, The EMBO journal.
[47] R. Huber,et al. Crystal structure of gingipain R: an Arg‐specific bacterial cysteine proteinase with a caspase‐like fold , 1999, The EMBO journal.
[48] J. R. Brown,et al. The GPI biosynthetic pathway as a therapeutic target for African sleeping sickness. , 1999, Biochimica et biophysica acta.
[49] P. Bork,et al. Prediction of potential GPI-modification sites in proprotein sequences. , 1999, Journal of molecular biology.
[50] M. Ferguson,et al. The structure, biosynthesis and functions of glycosylphosphatidylinositol anchors, and the contributions of trypanosome research. , 1999, Journal of cell science.
[51] R. Watanabe,et al. GPI1 Stabilizes an Enzyme Essential in the First Step of Glycosylphosphatidylinositol Biosynthesis* , 1999, The Journal of Biological Chemistry.
[52] A. Menon,et al. A Cell-free Assay for Glycosylphosphatidylinositol Anchoring in African Trypanosomes , 1999, The Journal of Biological Chemistry.
[53] F. Reggiori,et al. Deletion of GPI7, a Yeast Gene Required for Addition of a Side Chain to the Glycosylphosphatidylinositol (GPI) Core Structure, Affects GPI Protein Transport, Remodeling, and Cell Wall Integrity* , 1999, The Journal of Biological Chemistry.
[54] Terry K. Smith,et al. Segregation of Glycosylphosphatidylinositol Biosynthetic Reactions in a Subcompartment of the Endoplasmic Reticulum* , 1999, The Journal of Biological Chemistry.
[55] M. McConville,et al. Evidence that free GPI glycolipids are essential for growth of Leishmania mexicana , 1999, The EMBO journal.
[56] R. Watanabe,et al. Mammalian PIG-L and its yeast homologue Gpi12p are N-acetylglucosaminylphosphatidylinositol de-N-acetylases essential in glycosylphosphatidylinositol biosynthesis. , 1999, The Biochemical journal.
[57] S. Reed,et al. MCD4 encodes a conserved endoplasmic reticulum membrane protein essential for glycosylphosphatidylinositol anchor synthesis in yeast. , 1999, Molecular biology of the cell.
[58] M. Ferguson,et al. A Novel Glycosylphosphatidylinositol in African Trypanosomes , 1999, The Journal of Biological Chemistry.
[59] N. Rawlings,et al. Identification of the active site of legumain links it to caspases, clostripain and gingipains in a new clan of cysteine endopeptidases , 1998, FEBS letters.
[60] P Bork,et al. Sequence properties of GPI-anchored proteins near the omega-site: constraints for the polypeptide binding site of the putative transamidase. , 1998, Protein engineering.
[61] H. Aburatani,et al. Assignment of the human GPAA1 gene, which encodes a product required for the attachment of glycosylphosphatidylinositols to proteins, at 8q24. , 1998, Genomics.
[62] S F Altschul,et al. Iterated profile searches with PSI-BLAST--a tool for discovery in protein databases. , 1998, Trends in biochemical sciences.
[63] J. Thompson,et al. Multiple sequence alignment with Clustal X. , 1998, Trends in biochemical sciences.
[64] P. Orlean,et al. Human and mouse Gpi1p homologues restore glycosylphosphatidylinositol membrane anchor biosynthesis in yeast mutants. , 1998, The Biochemical journal.
[65] R. Watanabe,et al. DPM2 regulates biosynthesis of dolichol phosphate‐mannose in mammalian cells: correct subcellular localization and stabilization of DPM1, and binding of dolichol phosphate , 1998, The EMBO journal.
[66] László Polgár,et al. Prolyl Oligopeptidase An Unusual β-Propeller Domain Regulates Proteolysis , 1998, Cell.
[67] P. Gerold,et al. Saccharomyces cerevisiae GPI10, the functional homologue of human PIG-B, is required for glycosylphosphatidylinositol-anchor synthesis. , 1998, The Biochemical journal.
[68] H. Floss,et al. 3-Amino-5-hydroxybenzoic Acid Synthase, the Terminal Enzyme in the Formation of the Precursor of mC7N Units in Rifamycin and Related Antibiotics* , 1998, The Journal of Biological Chemistry.
[69] G. Byrne,et al. Glycosyl Phosphatidylinositol Anchor , 1998, Nephron Experimental Nephrology.
[70] P. Orlean,et al. The first step of glycosylphosphatidylinositol biosynthesis is mediated by a complex of PIG‐A, PIG‐H, PIG‐C and GPI1 , 1998, The EMBO journal.
[71] S. Kudoh,et al. Molecular cloning of human homolog of yeast GAA1 which is required for attachment of glycosylphosphatidylinositols to proteins 1 , 1998, FEBS letters.
[72] E. R. Norris,et al. Structural and functional analysis of the Pig-a protein that is mutated in paroxysmal nocturnal hemoglobinuria. , 1997, Blood cells, molecules & diseases.
[73] Terry K. Smith,et al. Parasite and mammalian GPI biosynthetic pathways can be distinguished using synthetic substrate analogues , 1997, The EMBO journal.
[74] A. Crossman,et al. Substrate specificity of the N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase of glycosylphosphatidylinositol membrane anchor biosynthesis in African trypanosomes and human cells. , 1997, The Biochemical journal.
[75] T. Fujita,et al. Structures and chromosomal localizations of the glycosylphosphatidylinositol synthesis gene PIGC and its pseudogene PIGCP1. , 1997, Genomics.
[76] O. Nosjean,et al. Mammalian GPI proteins: sorting, membrane residence and functions. , 1997, Biochimica et biophysica acta.
[77] A. Crossman,et al. Early steps in glycosylphosphatidylinositol biosynthesis in Leishmania major. , 1997, The Biochemical journal.
[78] Thomas L. Madden,et al. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. , 1997, Nucleic acids research.
[79] T. Kinoshita,et al. GPI-anchor synthesis in mammalian cells: genes, their products, and a deficiency. , 1997, Journal of biochemistry.
[80] V. Stevens,et al. Expression Cloning of PIG-L, a CandidateN-Acetylglucosaminyl-phosphatidylinositol Deacetylase* , 1997, The Journal of Biological Chemistry.
[81] A. Lupas,et al. Predicting coiled-coil regions in proteins. , 1997, Current opinion in structural biology.
[82] A Elofsson,et al. Prediction of transmembrane alpha-helices in prokaryotic membrane proteins: the dense alignment surface method. , 1997, Protein engineering.
[83] P Argos,et al. NADP‐Dependent enzymes. I: Conserved stereochemistry of cofactor binding , 1997, Proteins.
[84] H. Ikezawa,et al. The presence of GPI-linked protein(s) in an archaeobacterium, Sulfolobus acidocaldarius, closely related to eukaryotes. , 1997, Biochimica et biophysica acta.
[85] P. Orlean,et al. The Essential Schizosaccharomyces pombe gpi1+ Gene Complements a Bakers' Yeast GPI Anchoring Mutant and is Required for Efficient Cell Separation , 1997, Yeast.
[86] M. Aebi,et al. Yeast Gpi8p is essential for GPI anchor attachment onto proteins. , 1996, The EMBO journal.
[87] P. Orlean,et al. Gpi1, a Saccharomyces cerevisiae Protein That Participates in the First Step in Glycosylphosphatidylinositol Anchor Synthesis* , 1996, The Journal of Biological Chemistry.
[88] R. Watanabe,et al. PIG-A and PIG-H, Which Participate in Glycosylphosphatidylinositol Anchor Biosynthesis, Form a Protein Complex in the Endoplasmic Reticulum* , 1996, The Journal of Biological Chemistry.
[89] R. Watanabe,et al. PIG-C, one of the three human genes involved in the first step of glycosylphosphatidylinositol biosynthesis is a homologue of Saccharomyces cerevisiae GPI2. , 1996, Biochemical and biophysical research communications.
[90] T. Fujita,et al. PIG‐B, a membrane protein of the endoplasmic reticulum with a large lumenal domain, is involved in transferring the third mannose of the GPI anchor. , 1996, The EMBO journal.
[91] S. Udenfriend,et al. COOH-terminal processing of nascent polypeptides by the glycosylphosphatidylinositol transamidase in the presence of hydrazine is governed by the same parameters as glycosylphosphatidylinositol addition. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[92] D. Hoessli,et al. Transfer of exogenous glycosylphos-phatidylinositol (GPI)-linked molecules to plasma membranes. , 1996, Trends in cell biology.
[93] S. Udenfriend,et al. An Active Carbonyl Formed during Glycosylphosphatidylinositol Addition to a Protein Is Evidence of Catalysis by a Transamidase (*) , 1995, The Journal of Biological Chemistry.
[94] Nasir-ud-din,et al. Integration of mycobacterial lipoarabinomannans into glycosylphosphatidylinositol-rich domains of lymphomonocytic cell plasma membranes. , 1995, Journal of immunology.
[95] M. L. Güther,et al. The role of inositol acylation and inositol deacylation in GPI biosynthesis in Trypanosoma brucei. , 1995, The EMBO journal.
[96] J. Fassler,et al. Temperature-sensitive Yeast GPI Anchoring Mutants gpi2 and gpi3 Are Defective in the Synthesis of N-Acetylglucosaminyl Phosphatidylinositol. , 1995, The Journal of Biological Chemistry.
[97] Carolyn J. Brown,et al. Identification of a PIG-A related processed gene on chromosome 12 , 1995, Human Genetics.
[98] H. Schmidt,et al. Molecular characterization of the lincomycin‐production gene cluster of Streptomyces lincolnensis 78‐11 , 1995, Molecular microbiology.
[99] H. Riezman,et al. Yeast Gaa1p is required for attachment of a completed GPI anchor onto proteins , 1995, The Journal of cell biology.
[100] S. Udenfriend,et al. Cleavage without anchor addition accompanies the processing of a nascent protein to its glycosylphosphatidylinositol-anchored form. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[101] A. Menon,et al. The GPI anchor of cell-surface proteins is synthesized on the cytoplasmic face of the endoplasmic reticulum , 1994, The Journal of cell biology.
[102] Yoshinori Fujiyoshi,et al. Atomic model of plant light-harvesting complex by electron crystallography , 1994, Nature.
[103] J. Yu,et al. Characterization of alternatively spliced PIG-A transcripts in normal and paroxysmal nocturnal hemoglobinuria cells. , 1994, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
[104] T. Miyata,et al. Paroxysmal nocturnal haemoglobinuria (PNH) is caused by somatic mutations in the PIG‐A gene. , 1994, The EMBO journal.
[105] E. Yeh,et al. Correction of the class H defect in glycosylphosphatidylinositol anchor biosynthesis in Ltk- cells by a human cDNA clone. , 1993, The Journal of biological chemistry.
[106] A. Menon,et al. Early lipid intermediates in glycosyl-phosphatidylinositol anchor assembly are synthesized in the ER and located in the cytoplasmic leaflet of the ER membrane bilayer , 1993, The Journal of cell biology.
[107] T. Kinoshita,et al. Cloning of a human gene, PIG-F, a component of glycosylphosphatidylinositol anchor biosynthesis, by a novel expression cloning strategy. , 1993, The Journal of biological chemistry.
[108] T. Miyata,et al. The cloning of PIG-A, a component in the early step of GPI-anchor biosynthesis. , 1993, Science.
[109] L. Polgár. Prolyl endopeptidase catalysis. A physical rather than a chemical step is rate-limiting. , 1992, The Biochemical journal.
[110] S Karlin,et al. Methods and algorithms for statistical analysis of protein sequences. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[111] L. Ravi,et al. Assembly and deacetylation of N-acetylglucosaminyl-plasmanylinositol in normal and affected paroxysmal nocturnal hemoglobinuria cells. , 1991, Proceedings of the National Academy of Sciences of the United States of America.
[112] G. Hart,et al. Biosynthesis of the glycosyl phosphatidylinositol membrane anchor of the trypanosome variant surface glycoprotein. Origin of the non-acetylated glucosamine. , 1989, The Journal of biological chemistry.
[113] P. Orlean,et al. Cloning and sequencing of the yeast gene for dolichol phosphate mannose synthase, an essential protein. , 1988, The Journal of biological chemistry.
[114] Benjamin A. Shoemaker,et al. CDD: a database of conserved domain alignments with links to domain three-dimensional structure , 2002, Nucleic Acids Res..
[115] P Bork,et al. Post-translational GPI lipid anchor modification of proteins in kingdoms of life: analysis of protein sequence data from complete genomes. , 2001, Protein engineering.
[116] Michael Y. Galperin,et al. The COG database: new developments in phylogenetic classification of proteins from complete genomes , 2001, Nucleic Acids Res..
[117] M. Hattori,et al. A novel gene, DSCR5, from the distal Down syndrome critical region on chromosome 21q22.2. , 2000, DNA research : an international journal for rapid publication of reports on genes and genomes.
[118] Yigong Shi,et al. The 1.9 Å crystal structure of Escherichia coli MurG, a membrane‐associated glycosyltransferase involved in peptidoglycan biosynthesis , 2000, Protein science : a publication of the Protein Society.
[119] H Nielsen,et al. Machine learning approaches for the prediction of signal peptides and other protein sorting signals. , 1999, Protein engineering.
[120] Geoffrey J. Barton,et al. JPred : a consensus secondary structure prediction server , 1999 .
[121] Amos Bairoch,et al. The PROSITE database, its status in 1999 , 1999, Nucleic Acids Res..
[122] S. Eddy. Profile hidden Markov models , 1998, Bioinform..
[123] Michelle T. Harreman,et al. Isolation and characterization of a Chinese hamster ovary (CHO) mutant defective in the second step of glycosylphosphatidylinositol biosynthesis. , 1996, The Biochemical journal.
[124] J. Wootton,et al. Analysis of compositionally biased regions in sequence databases. , 1996, Methods in enzymology.
[125] S Udenfriend,et al. How glycosylphosphatidylinositol-anchored membrane proteins are made. , 1995, Annual review of biochemistry.
[126] S. Udenfriend,et al. [39] Processing of nascent proteins to glycosylphosphatidylinositol-anchored forms in cell-free systems , 1995 .
[127] H. Nikaido,et al. The envelope of mycobacteria. , 1995, Annual review of biochemistry.
[128] G. Heijne. Membrane protein structure prediction. Hydrophobicity analysis and the positive-inside rule. , 1992, Journal of molecular biology.
[129] S Karlin,et al. Significant similarity and dissimilarity in homologous proteins. , 1992, Molecular biology and evolution.
[130] G. Feher,et al. The bacterial photosynthetic reaction center as a model for membrane proteins. , 1989, Annual review of biochemistry.