Opioids prevent regeneration in adult mammals through inhibition of ROS production

[1]  Sabita Roy,et al.  Opioids Impair Intestinal Epithelial Repair in HIV-Infected Humanized Mice , 2020, Frontiers in Immunology.

[2]  A. Joliot,et al.  Hydrogen Peroxide and Redox Regulation of Developments , 2018, Antioxidants.

[3]  Sabita Roy,et al.  Morphine worsens the severity and prevents pancreatic regeneration in mouse models of acute pancreatitis , 2017, Gut.

[4]  Ashley W Seifert,et al.  Macrophages are necessary for epimorphic regeneration in African spiny mice , 2017, eLife.

[5]  P. Ravaud,et al.  An Innovative, Comprehensive Mapping and Multiscale Analysis of Registered Trials for Stem Cell‐Based Regenerative Medicine , 2016, Stem cells translational medicine.

[6]  Carole Gauron,et al.  Nerves Control Redox Levels in Mature Tissues Through Schwann Cells and Hedgehog Signaling , 2016, Antioxidants & redox signaling.

[7]  Yan Liu,et al.  Reactive oxygen species generated from skeletal muscles are required for gecko tail regeneration , 2016, Scientific Reports.

[8]  D. Morgan,et al.  Update on Medical Practices That Should Be Questioned in 2015. , 2015, JAMA internal medicine.

[9]  Daniel A. Berg,et al.  Environmental changes in oxygen tension reveal ROS-dependent neurogenesis and regeneration in the adult newt brain , 2015, eLife.

[10]  M. Plusquin,et al.  Reactive Oxygen Species in Planarian Regeneration: An Upstream Necessity for Correct Patterning and Brain Formation , 2015, Oxidative medicine and cellular longevity.

[11]  Chuan-Yun Li,et al.  Hydrogen peroxide primes heart regeneration with a derepression mechanism , 2014, Cell Research.

[12]  S. Reddy,et al.  Reactive oxygen species in inflammation and tissue injury. , 2014, Antioxidants & redox signaling.

[13]  Bruce M. Spiegelman,et al.  What We Talk About When We Talk About Fat , 2014, Cell.

[14]  D. Hyde,et al.  The zebrafish as a model for complex tissue regeneration. , 2013, Trends in genetics : TIG.

[15]  J. Novotný,et al.  Morphine as a Potential Oxidative Stress-Causing Agent , 2013, Mini-reviews in organic chemistry.

[16]  Mohamed Bouzaffour,et al.  Sustained production of ROS triggers compensatory proliferation and is required for regeneration to proceed , 2013, Scientific Reports.

[17]  C. Stein,et al.  Targeting inflammation and wound healing by opioids. , 2013, Trends in pharmacological sciences.

[18]  E. Amaya,et al.  Amputation-induced reactive oxygen species (ROS) are required for successful Xenopus tadpole tail regeneration , 2013, Nature Cell Biology.

[19]  W. Hasan,et al.  Morphine-induced early delays in wound closure: involvement of sensory neuropeptides and modification of neurokinin receptor expression. , 2009, Biochemical pharmacology.

[20]  Timothy J. Mitchison,et al.  A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish , 2009, Nature.

[21]  M. Korostyński,et al.  Local peripheral opioid effects and expression of opioid genes in the spinal cord and dorsal root ganglia in neuropathic and inflammatory pain , 2009, PAIN.

[22]  C. Stein,et al.  Peripheral mechanisms of opioid analgesia. , 2009, Current opinion in pharmacology.

[23]  Anoop Kumar,et al.  The Immunoglobulin-Like Cell Adhesion Molecule Nectin and Its Associated Protein , 2011 .

[24]  W. Hasan,et al.  Temporal Effects of Topical Morphine Application on Cutaneous Wound Healing , 2008, Anesthesiology.

[25]  J. Gimble,et al.  Adipose-derived stem cells for regenerative medicine. , 2007, Circulation research.

[26]  B. Lévy,et al.  Plasticity of Human Adipose Lineage Cells Toward Endothelial Cells: Physiological and Therapeutic Perspectives , 2004, Circulation.

[27]  C. Stein,et al.  Intraarticular morphine versus dexamethasone in chronic arthritis , 1999, PAIN®.

[28]  M. Austrup,et al.  Analgesic agents for the postoperative period. Opioids. , 1999, The Surgical clinics of North America.

[29]  I. Power,et al.  Analgesic agents for the postoperative period. Nonopioids. , 1999, The Surgical clinics of North America.

[30]  L. Clark,et al.  A new murine model for mammalian wound repair and regeneration. , 1998, Clinical immunology and immunopathology.

[31]  J. Stolk,et al.  Characteristics of the inhibition of NADPH oxidase activation in neutrophils by apocynin, a methoxy-substituted catechol. , 1994, American journal of respiratory cell and molecular biology.

[32]  C. Stein,et al.  Local analgesic effect of endogenous opioid peptides , 1993, The Lancet.

[33]  L. Pénicaud,et al.  Occurrence of brown adipocytes in rat white adipose tissue: molecular and morphological characterization. , 1992, Journal of cell science.

[34]  A. Herz,et al.  Intrinsic mechanisms of antinociception in inflammation: local opioid receptors and beta-endorphin , 1990, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[35]  S. Vriz,et al.  Cell death: a program to regenerate. , 2014, Current topics in developmental biology.

[36]  Sabita Roy,et al.  Chronic morphine treatment inhibits LPS-induced angiogenesis: implications in wound healing. , 2010, Cellular immunology.

[37]  G. Fricchione,et al.  Opioid and opiate immunoregulatory processes. , 1996, Critical reviews in immunology.