The contribution of endogenous sources of DNA damage to the multiple mutations in cancer.
暂无分享,去创建一个
[1] J. V. Frei,et al. Hereditary nonpolyposis colorectal cancer (Lynch syndrome II). Diploid malignancies with prolonged survival. , 1992, Cancer.
[2] Roger Woodgate,et al. Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis , 2000, Nature.
[3] Robert E. Johnson,et al. The human DINB1 gene encodes the DNA polymerase Poltheta. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[4] S. Thorgeirsson,et al. Vitamin E reduces chromosomal damage and inhibits hepatic tumor formation in a transgenic mouse model. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[5] A. Jackson,et al. Microsatellite instability induced by hydrogen peroxide in Escherichia coli. , 2000, Mutation research.
[6] M. Bronner,et al. Pancolonic chromosomal instability precedes dysplasia and cancer in ulcerative colitis. , 1999, Cancer research.
[7] Y. Suh,et al. Cell transformation by the superoxide-generating oxidase Mox1 , 1999, Nature.
[8] E. Friedberg,et al. Novel DNA Polymerases Offer Clues to the Molecular Basis of Mutagenesis , 1999, Cell.
[9] E. G. Frank,et al. UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[10] Robert E. Johnson,et al. hRAD30 mutations in the variant form of xeroderma pigmentosum. , 1999, Science.
[11] Chikahide Masutani,et al. The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase η , 1999, Nature.
[12] F. Hanaoka,et al. Xeroderma pigmentosum variant (XP‐V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity , 1999, The EMBO journal.
[13] P. Duesberg,et al. How aneuploidy affects metabolic control and causes cancer. , 1999, The Biochemical journal.
[14] J. Hays,et al. Specific Binding of Human MSH2·MSH6 Mismatch-Repair Protein Heterodimers to DNA Incorporating Thymine- or Uracil-containing UV Light Photoproducts Opposite Mismatched Bases* , 1999, The Journal of Biological Chemistry.
[15] F. Waldman,et al. Genomic instability is an early event during the progression pathway of ulcerative-colitis-related neoplasia. , 1999, The American journal of pathology.
[16] Samuel H. Wilson,et al. DNA polymerase β expression differences in selected human tumors and cell lines , 1999 .
[17] L. Loeb,et al. Detection of tandem CC-->TT mutations induced by oxygen radicals using mutation-specific PCR. , 1999, Mutation research.
[18] J. Swenberg,et al. Endogenous apurinic/apyrimidinic sites in genomic DNA of mammalian tissues. , 1999, Cancer research.
[19] Y. Canitrot,et al. Overexpression of DNA polymerase β: a genomic instability enhancer process , 1999, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[20] M. Speicher,et al. Comparative genomic hybridization, loss of heterozygosity, and DNA sequence analysis of single cells. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[21] Robert E. Johnson,et al. Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Poleta. , 1999, Science.
[22] P. Duesberg,et al. Genetic instability of cancer cells is proportional to their degree of aneuploidy. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[23] A. Jackson,et al. Induction of microsatellite instability by oxidative DNA damage. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[24] Y. Canitrot,et al. Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[25] Harris Cc,et al. Molecular epidemiology of human cancer: contribution of mutation spectra studies of tumor suppressor genes. , 1998 .
[26] S. Knuutila,et al. DNA copy number changes in development and progression in leiomyosarcomas of soft tissues. , 1998, The American journal of pathology.
[27] C. Griffin,et al. Genetic analysis of ovarian germ cell tumors by comparative genomic hybridization. , 1998, Cancer research.
[28] S. Knuutila,et al. DNA copy number amplifications in human neoplasms: review of comparative genomic hybridization studies. , 1998, The American journal of pathology.
[29] A. Jackson,et al. The mutation rate and cancer. , 1998, Genetics.
[30] D. A. Kreutzer,et al. Oxidized, deaminated cytosines are a source of C --> T transitions in vivo. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[31] M. Rugge,et al. Oxidative DNA damage accumulation in gastric carcinogenesis , 1998, Gut.
[32] H. Yamamoto,et al. Somatic frameshift mutations in DNA mismatch repair and proapoptosis genes in hereditary nonpolyposis colorectal cancer. , 1998, Cancer research.
[33] Peter Lichter,et al. Minimal sizes of deletions detected by comparative genomic hybridization , 1998, Genes, chromosomes & cancer.
[34] L. Loeb,et al. Oxidative DNA Damage and Mutagenesis , 1998 .
[35] D. Birnbaum,et al. Genome-wide search for loss of heterozygosity shows extensive genetic diversity of human breast carcinomas. , 1997, Cancer research.
[36] D. A. Kreutzer,et al. Synthesis of oligonucleotides containing two putatively mutagenic DNA lesions: 5-hydroxy-2'-deoxyuridine and 5-hydroxy-2'-deoxycytidine. , 1997, Chemical research in toxicology.
[37] B. Ames,et al. Oxidative Decay of DNA* , 1997, The Journal of Biological Chemistry.
[38] R. Oyasu,et al. Tumorigenic conversion of a non‐tumorigenic rat urothelial cell line by overexpression of H2O2‐generating peroxisomal fatty acyl‐CoA oxidase , 1997, International journal of cancer.
[39] B. Preston,et al. A genetic system to identify DNA polymerase β mutator mutants , 1997 .
[40] J C Reed,et al. Somatic Frameshift Mutations in the BAX Gene in Colon Cancers of the Microsatellite Mutator Phenotype , 1997, Science.
[41] Amanda G Paulovich,et al. When Checkpoints Fail , 1997, Cell.
[42] M. Makuuchi,et al. A transforming growth factor beta type II receptor gene mutation common in sporadic cecum cancer with microsatellite instability. , 1996, Cancer research.
[43] A. Krayevsky,et al. Proliferating Cell Nuclear Antigen Promotes Misincorporation Catalyzed by Calf Thymus DNA Polymerase δ* , 1996, The Journal of Biological Chemistry.
[44] J. Reddy,et al. Transformation of epithelial cells stably transfected with H2O2-generating peroxisomal urate oxidase. , 1996, Cancer research.
[45] K. Kinzler,et al. APC mutations in colorectal tumors with mismatch repair deficiency. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[46] C. Lawrence,et al. Thymine-Thymine Dimer Bypass by Yeast DNA Polymerase ζ , 1996, Science.
[47] T. Kunkel,et al. DNA-replication fidelity, mismatch repair and genome instability in cancer cells. , 1996, European journal of biochemistry.
[48] M. Rugge,et al. Gastric antioxidant, nitrites, and mucosal lipoperoxidation in chronic gastritis and Helicobacter pylori infection. , 1996, Journal of clinical gastroenterology.
[49] M. Chung,et al. Increased oxidative DNA damage in Helicobacter pylori-infected human gastric mucosa. , 1996, Cancer research.
[50] Sajeev P. Cherian,et al. Microsatellite instability in nonneoplastic mucosa from patients with chronic ulcerative colitis. , 1996, Cancer research.
[51] R. Christopherson,et al. Purine deoxynucleoside metabolism in human melanoma cells with a high spontaneous mutation rate. , 1996, Mutation research.
[52] M. Kimmey,et al. Risk and natural history of colonic neoplasia in patients with primary sclerosing cholangitis and ulcerative colitis. , 1996, Gastroenterology.
[53] J. Sweasy,et al. Dominant negative rat DNA polymerase beta mutants interfere with base excision repair in Saccharomyces cerevisiae , 1996, Journal of bacteriology.
[54] Samuel H. Wilson,et al. Requirement of mammalian DNA polymerase-β in base-excision repair , 1996, Nature.
[55] D. Pinkel,et al. Genetic analysis of benign, low-grade, and high-grade ovarian tumors. , 1995, Cancer research.
[56] K. Kinzler,et al. Microsatellite instability and mutations of the transforming growth factor beta type II receptor gene in colorectal cancer. , 1995, Cancer research.
[57] M. Kimmey,et al. Microsatellite instability and K-ras mutations associated with pancreatic adenocarcinoma and pancreatitis. , 1995, Cancer research.
[58] R. Hindges,et al. Production of active mouse DNA polymerase β in bacteria , 1995 .
[59] K. Kinzler,et al. Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. , 1995, Science.
[60] A. Floreani,et al. Iron storage, lipid peroxidation and glutathione turnover in chronic anti-HCV positive hepatitis. , 1995, Journal of hepatology.
[61] B. Ames,et al. Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[62] L. Hartwell,et al. Cell cycle control and cancer. , 1994, Science.
[63] L. Loeb,et al. Reverse chemical mutagenesis: identification of the mutagenic lesions resulting from reactive oxygen species-mediated damage to DNA. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[64] S. Hirohashi,et al. Increased formation of oxidative DNA damage, 8-hydroxydeoxyguanosine, in human livers with chronic hepatitis. , 1994, Cancer research.
[65] J. Hoofnagle,et al. Classification of chronic hepatitis: Diagnosis, grading and staging , 1994, Hepatology.
[66] L. Loeb,et al. The fragile X syndrome d(CGG)n nucleotide repeats form a stable tetrahelical structure. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[67] R. Fleischmann,et al. Mutation of a mutL homolog in hereditary colon cancer. , 1994, Science.
[68] J Piper,et al. Detection and mapping of amplified DNA sequences in breast cancer by comparative genomic hybridization. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[69] D. Shibata,et al. Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation , 1994, Nature Genetics.
[70] Susan S. Wallace,et al. Major oxidative products of cytosine, 5-hydroxycytosine and 5- hydroxyuracil, exhibit sequence context-dependent mispairing in vitro , 1994, Nucleic Acids Res..
[71] L. Loeb,et al. Oxygen radical induced mutagenesis is DNA polymerase specific. , 1994, Journal of molecular biology.
[72] Robin J. Leach,et al. Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer , 1993, Cell.
[73] N. Copeland,et al. The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer , 1993, Cell.
[74] R. Schaaper. Base selection, proofreading, and mismatch repair during DNA replication in Escherichia coli. , 1993, The Journal of biological chemistry.
[75] R. Floyd. Measurement of oxidative stress in vivo , 1993 .
[76] Tomas A. Prolla,et al. Destabilization of tracts of simple repetitive DNA in yeast by mutations affecting DNA mismatch repair , 1993, Nature.
[77] B. Ames,et al. Oxidants, antioxidants, and the degenerative diseases of aging. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[78] H. Koeffler,et al. Regulation of manganese superoxide dismutase and other antioxidant genes in normal and leukemic hematopoietic cells and their relationship to cytotoxicity by tumor necrosis factor. , 1993, Blood.
[79] Darryl Shibata,et al. Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis , 1993, Nature.
[80] L. Loeb,et al. Tandem double CC-->TT mutations are produced by reactive oxygen species. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[81] L. Loeb,et al. Mutations induced by methylene blue plus light in single-stranded M13mp2. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[82] B. Henderson,et al. Urinary aflatoxin biomarkers and risk of hepatocellular carcinoma , 1992, The Lancet.
[83] L. Loeb,et al. Mammalian DNA polymerase beta can substitute for DNA polymerase I during DNA replication in Escherichia coli. , 1992, The Journal of biological chemistry.
[84] L. Loeb,et al. 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G----T and A----C substitutions. , 1992, The Journal of biological chemistry.
[85] P. Burgers,et al. The spectrum of spontaneous mutations in a Saccharomyces cerevisiae uracil-DNA-glycosylase mutant limits the function of this enzyme to cytosine deamination repair , 1991, Journal of bacteriology.
[86] L. Loeb,et al. Mutator phenotype may be required for multistage carcinogenesis. , 1991, Cancer research.
[87] A. Grollman,et al. Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG , 1991, Nature.
[88] G. Coetzee,et al. 5-Methylcytosine as an endogenous mutagen in the human LDL receptor and p53 genes. , 1990, Science.
[89] S. Jain,et al. DNA polymerases alpha, delta, and epsilon: three distinct enzymes from HeLa cells. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[90] S. Weitzman,et al. Inflammation and cancer: role of phagocyte-generated oxidants in , 2011 .
[91] J. Essigmann,et al. Mechanistic studies of ionizing radiation and oxidative mutagenesis: genetic effects of a single 8-hydroxyguanine (7-hydro-8-oxoguanine) residue inserted at a unique site in a viral genome. , 1990, Biochemistry.
[92] B. Vogelstein,et al. A genetic model for colorectal tumorigenesis , 1990, Cell.
[93] K. Franssila,et al. Diploid predominance in hereditary nonpolyposis colorectal carcinoma evaluated by flow cytometry , 1990, Cancer.
[94] B H Margolin,et al. Differences in the rates of gene amplification in nontumorigenic and tumorigenic cell lines as measured by Luria-Delbrück fluctuation analysis. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[95] K. Tindall,et al. Changes in DNA base sequence induced by gamma-ray mutagenesis of lambda phage and prophage. , 1988, Genetics.
[96] R. Schaaper,et al. Metal-induced lethality and mutagenesis: possible role of apurinic intermediates. , 1987, Mutation research.
[97] S. Weitzman,et al. Phagocytes as carcinogens: malignant transformation produced by human neutrophils. , 1985, Science.
[98] L. Loeb. Apurinic sites as mutagenic intermediates , 1985, Cell.
[99] J. Cadet,et al. Radiation-induced decomposition of the purine bases within DNA and related model compounds. , 1985, International journal of radiation biology and related studies in physics, chemistry, and medicine.
[100] P. Cerutti. Prooxidant states and tumor promotion. , 1985, Science.
[101] B. Ames,et al. Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseases. , 1983, Science.
[102] L. Triplett,et al. Skin tumor-promoting activity of benzoyl peroxide, a widely used free radical-generating compound. , 1981, Science.
[103] Jeffrey H. Miller,et al. Mutagenic deamination of cytosine residues in DNA , 1980, Nature.
[104] J. Hesser,et al. The relation of infection with the hepatitis B agent to primary hepatic carcinoma. , 1975, The American journal of pathology.
[105] L. Loeb,et al. Errors in DNA replication as a basis of malignant changes. , 1974, Cancer research.
[106] B Nyberg,et al. Heat-induced deamination of cytosine residues in deoxyribonucleic acid. , 1974, Biochemistry.
[107] R. Teoule,et al. Identification of Radiolysis Products of Cytosine Resulting from the Deamination Pathway , 1974, Zeitschrift fur Naturforschung. Section C, Biosciences.
[108] T. Lindahl,et al. Rate of depurination of native deoxyribonucleic acid. , 1972, Biochemistry.
[109] A. Jackson,et al. Origin of multiple mutations in human cancers. , 1998, Drug metabolism reviews.
[110] P. Modrich,et al. Mismatch repair in replication fidelity, genetic recombination, and cancer biology. , 1996, Annual review of biochemistry.
[111] D. V. van Thiel,et al. Association between reactive oxygen species and disease activity in chronic hepatitis C. , 1996, Free radical biology & medicine.
[112] B. Leggett,et al. Microsatellite instability in the insulin–like growth factor II receptor gene in gastrointestinal tumours , 1996, Nature Genetics.
[113] J. Perchellet,et al. Antioxidants and multistage carcinogenesis in mouse skin. , 1989, Free radical biology & medicine.
[114] P. D. de Jong,et al. Base substitutions, frameshifts, and small deletions constitute ionizing radiation-induced point mutations in mammalian cells. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[115] Miller Rw. Geographical and ethnic differences in the occurrence of childhood cancer. , 1988 .
[116] B. Taffe,et al. Activation of Organic Hydroperoxide Tumor Promoters to Free Radicals in Target Cells , 1987 .
[117] J. Minna,et al. Loss of heterozygosity of chromosome 3p markers in small-cell lung cancer , 1987, Nature.
[118] L. Loeb,et al. Mutagenesis by apurinic/apyrimidinic sites. , 1986, Annual review of genetics.
[119] P. Nowell,et al. Karyotypic evolution in human malignant melanoma. , 1986, Cancer genetics and cytogenetics.
[120] E. Witkin. Ultraviolet mutagenesis and inducible DNA repair in Escherichia coli. , 1976, Bacteriological reviews.
[121] J. Rowley. Nonrandom chromosomal abnormalities in hematologic disorders of man. , 1975, Proceedings of the National Academy of Sciences of the United States of America.