Ultrasound evaluation of fetal nasal bone at 11 to 14 weeks in a consecutive series of 1906 fetuses

The aim of this study is to evaluate the significance of nasal bone ossification as a marker for trisomy 21 at 11 to 14 weeks' gestation in an unselected obstetric population referred to our Centre.

[1]  C. Bilardo,et al.  Measurement of nasal bone length at 11–14 weeks of pregnancy and its potential role in Down syndrome risk assessment , 2003, Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology.

[2]  S. Cicero,et al.  Integrated ultrasound and biochemical screening for trisomy 21 using fetal nuchal translucency, absent fetal nasal bone, free β‐hCG and PAPP‐A at 11 to 14 weeks , 2003, Prenatal diagnosis.

[3]  E. Gadow,et al.  Association between first trimester absence of fetal nasal bone on ultrasound and Down syndrome , 2002, Prenatal diagnosis.

[4]  H. Cuckle.  Absence of nasal bone and detection of trisomy 21 , 2002, The Lancet.

[5]  T. Reynolds.  Absence of nasal bone and detection of trisomy 21 , 2002, The Lancet.

[6]  S. Cicero,et al.  Fetal nasal bone length in chromosomally normal and abnormal fetuses at 11–14 weeks of gestation , 2002, The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians.

[7]  H. Cuckle.  Time for total shift to first-trimester screening for Down's syndrome , 2001, The Lancet.

[8]  S. Cicero,et al.  Absence of nasal bone in fetuses with trisomy 21 at 11–14 weeks of gestation: an observational study , 2001, The Lancet.