Topical Gel Formulation Incorporated with Hydroalcoholic Extract of Stevia rebaudiana Bertoni

Herbal cosmeceuticals are more acceptable due to lower side effects from ages. Herb like Stevia rebaudiana Bertoni. is widely utilized as natural sweetener and recently extending applications in cosmeceutical industry due to its antioxidant characteristics which is acclaimed for antiaging properties. The objective of present investigation is to develop a topical gel formulation containing Stevia leaf hydroalcoholic extract. As gel provides more penetration than other conventional topical formulations, this antioxidant gel can help to achieve maximum penetration of antioxidants along with improved patient compliance. Steviosides and rebaudiosides the active ingredients of Stevia acting as natural sweeteners, also shows antioxidant activity due to presence of secondary phytoconstituents such as flavonoid’s, volatile oils, diterpenes etc. Considering this benefit of stevia, antioxidant gel formulation was developed, prepared in 4 batches (F1 to F4) using different concentrations of polymers (HPMC and Carbopol) along with Acacia as a natural viscosity modifier. The prepared batches were evaluated based on various parameters and optimum batch was identified. F2 seem to be optimum batch as it shown high stable content of stevioside and rebaudioside and was well fitted in other pharmaceutical parameters indicating effective use of stevia extract in gel system which may be a promising formulation.