Suppressor of Fused Regulates Gli Activity through a Dual Binding Mechanism
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M. Ultsch | A. D. de Vos | F. D. de Sauvage | M. Merchant | W. Desmarais | F. Vajdos | R. Lazarus | H. R. Maun | U. Wendt | J. Cannon | H. Maun
[1] Jin Jiang,et al. Multiple Cos2/Ci interactions regulate Ci subcellular localization through microtubule dependent and independent mechanisms. , 2004, Developmental biology.
[2] D. Boucher,et al. The negative regulator of Gli, Suppressor of fused (Sufu), interacts with SAP18, Galectin3 and other nuclear proteins. , 2004, The Biochemical journal.
[3] M. Ascano,et al. The Kinesin-related Protein Costal2 Associates with Membranes in a Hedgehog-sensitive, Smoothened-independent Manner* , 2004, Journal of Biological Chemistry.
[4] M. Ascano,et al. Identification of a Functional Interaction between the Transmembrane Protein Smoothened and the Kinesin-Related Protein Costal2 , 2003, Current Biology.
[5] L. Lum,et al. Hedgehog signal transduction via Smoothened association with a cytoplasmic complex scaffolded by the atypical kinesin, Costal-2. , 2003, Molecular cell.
[6] L. Ruel,et al. Stability and association of Smoothened, Costal2 and Fused with Cubitus interruptus are regulated by Hedgehog , 2003, Nature Cell Biology.
[7] M. Scott,et al. Altered localization of Drosophila Smoothened protein activates Hedgehog signal transduction. , 2003, Genes & development.
[8] P. Kogerman,et al. Characterization of the Physical Interaction of Gli Proteins with SUFU Proteins* , 2003, The Journal of Biological Chemistry.
[9] J. Gruenberg,et al. Sonic Hedgehog Induces the Segregation of Patched and Smoothened in Endosomes , 2002, Current Biology.
[10] J. Bishop,et al. Suppressor of Fused represses Gli-mediated transcription by recruiting the SAP18-mSin3 corepressor complex , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[11] B. Wang,et al. Shaggy/GSK3 antagonizes Hedgehog signalling by regulating Cubitus interruptus , 2002, Nature.
[12] D. Kalderon,et al. Proteolysis of the Hedgehog Signaling Effector Cubitus interruptus Requires Phosphorylation by Glycogen Synthase Kinase 3 and Casein Kinase 1 , 2002, Cell.
[13] M. Scott,et al. Hedgehog signal transduction proteins: contacts of the Fused kinase and Ci transcription factor with the Kinesin-related protein Costal2 , 2002, BMC Developmental Biology.
[14] M. Ascano,et al. The Carboxyl-Terminal Domain of the Protein Kinase Fused Can Function as a Dominant Inhibitor of Hedgehog Signaling , 2002, Molecular and Cellular Biology.
[15] P. Ingham,et al. Hedgehog signaling in animal development: paradigms and principles. , 2001, Genes & development.
[16] A. Corbett,et al. Interaction between Ran and Mog1 Is Required for Efficient Nuclear Protein Import* , 2001, The Journal of Biological Chemistry.
[17] B. Paschal,et al. Identification of a Conserved Loop in Mog1 that Releases GTP from Ran , 2001, Traffic.
[18] F. Gurrieri,et al. Genomic organization and embryonic expression of Suppressor of Fused, a candidate gene for the split‐hand/split‐foot malformation type 3 , 2001, FEBS letters.
[19] Isabel Guerrero,et al. The sterol-sensing domain of Patched protein seems to control Smoothened activity through Patched vesicular trafficking , 2001, Current Biology.
[20] P. Vertino,et al. Identification and characterization of the human MOG1 gene. , 2001, Gene.
[21] N. Méthot,et al. An absolute requirement for Cubitus interruptus in Hedgehog signaling. , 2001, Development.
[22] J. Jiang,et al. Interactions with Costal2 and suppressor of fused regulate nuclear translocation and activity of cubitus interruptus. , 2000, Genes & development.
[23] P. Ingham,et al. Patched represses the Hedgehog signalling pathway by promoting modification of the Smoothened protein , 2000, Current Biology.
[24] N. Méthot,et al. Suppressor of fused opposes hedgehog signal transduction by impeding nuclear accumulation of the activator form of Cubitus interruptus. , 2000, Development.
[25] S. Cohen,et al. Hedgehog Induces Opposite Changes in Turnover and Subcellular Localization of Patched and Smoothened , 2000, Cell.
[26] J. Guénet,et al. Genomic organization, chromosomal assignment, and expression analysis of the mouse Suppressor of fused gene (Sufu) coding a Gli protein partner , 2000, Mammalian Genome.
[27] Y. Zou,et al. Posttranscriptional regulation of smoothened is part of a self-correcting mechanism in the Hedgehog signaling system. , 2000, Molecular cell.
[28] D. Robbins,et al. Identification of a Tetrameric Hedgehog Signaling Complex* , 2000, The Journal of Biological Chemistry.
[29] M. Stewart,et al. 1.9 A resolution crystal structure of the Saccharomyces cerevisiae Ran-binding protein Mog1p. , 2000, Journal of molecular biology.
[30] A. Gurney,et al. Gli regulation by the opposing activities of Fused and Suppressor of Fused , 2000, Nature Cell Biology.
[31] Guoguang Lu,et al. TOP: a new method for protein structure comparisons and similarity searches , 2000 .
[32] A. Rosenthal,et al. Characterization of the human suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli. , 1999, Journal of cell science.
[33] J. Jiang,et al. Protein kinase A antagonizes Hedgehog signaling by regulating both the activator and repressor forms of Cubitus interruptus. , 1999, Genes & development.
[34] M. Nakafuku,et al. Mouse Suppressor of fused is a negative regulator of Sonic hedgehog signaling and alters the subcellular distribution of Gli1 , 1999, Current Biology.
[35] G. Sheldrick,et al. Advances in direct methods for protein crystallography. , 1999, Current opinion in structural biology.
[36] D. Krause,et al. Mammalian Suppressor-of-Fused modulates nuclear–cytoplasmic shuttling of GLI-1 , 1999, Nature Cell Biology.
[37] M. Nakafuku,et al. Regulation of Gli2 and Gli3 activities by an amino-terminal repression domain: implication of Gli2 and Gli3 as primary mediators of Shh signaling. , 1999, Development.
[38] M. Scott,et al. Vertebrate homologs of Drosophila suppressor of fused interact with the gli family of transcriptional regulators. , 1999, Developmental biology.
[39] R. Goodman,et al. Mutants of cubitus interruptus that are independent of PKA regulation are independent of hedgehog signaling. , 1999, Development.
[40] M. Delattre,et al. The Suppressor of fused gene, involved in Hedgehog signal transduction in Drosophila, is conserved in mammals , 1999, Development Genes and Evolution.
[41] Konrad Basler,et al. Hedgehog Controls Limb Development by Regulating the Activities of Distinct Transcriptional Activator and Repressor Forms of Cubitus interruptus , 1999, Cell.
[42] D. Kalderon,et al. Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator , 1998, Nature.
[43] R J Read,et al. Crystallography & NMR system: A new software suite for macromolecular structure determination. , 1998, Acta crystallographica. Section D, Biological crystallography.
[44] A. R. I. Altaba. Combinatorial Gli Gene Function in Floor Plate and Neuronal Inductions by Sonic Hedgehog , 1998 .
[45] A. Plessis,et al. Suppressor of fused links Fused and Cubitus interruptus on the Hedgehog signalling pathway , 1998, Current Biology.
[46] R. Goodman,et al. Protein kinase A directly regulates the activity and proteolysis of cubitus interruptus. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[47] M. Scott,et al. Costal2, a Novel Kinesin-Related Protein in the Hedgehog Signaling Pathway , 1997, Cell.
[48] R. Kobayashi,et al. Hedgehog Elicits Signal Transduction by Means of a Large Complex Containing the Kinesin-Related Protein Costal2 , 1997, Cell.
[49] A. Gurney,et al. Control of Cell Pattern in the Neural Tube by the Zinc Finger Transcription Factor and Oncogene Gli-1 , 1997, Neuron.
[50] T. Kornberg,et al. Proteolysis That Is Inhibited by Hedgehog Targets Cubitus interruptus Protein to the Nucleus and Converts It to a Repressor , 1997, Cell.
[51] R. Read,et al. Cross-validated maximum likelihood enhances crystallographic simulated annealing refinement. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[52] M. Scott,et al. The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog , 1996, Nature.
[53] C. Tabin,et al. Biochemical evidence that Patched is the Hedgehog receptor , 1996, Nature.
[54] G. Struhl,et al. Dual Roles for Patched in Sequestering and Transducing Hedgehog , 1996, Cell.
[55] R. Read,et al. Improved Structure Refinement Through Maximum Likelihood , 1996 .
[56] P. Ingham,et al. Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins. , 1996, Genes & development.
[57] P. Ingham,et al. smoothened encodes a receptor-like serpentine protein required for hedgehog signalling , 1996, Nature.
[58] M. Noll,et al. The Drosophila smoothened Gene Encodes a Seven-Pass Membrane Protein, a Putative Receptor for the Hedgehog Signal , 1996, Cell.
[59] M. Levine,et al. Protein kinase A is a common negative regulator of Hedgehog signaling in the vertebrate embryo. , 1996, Genes & development.
[60] D. Strutt,et al. Regulation of furrow progression in the Drosophila eye by cAMP-dependent protein kinase A , 1995, Nature.
[61] Collaborative Computational,et al. The CCP4 suite: programs for protein crystallography. , 1994, Acta crystallographica. Section D, Biological crystallography.
[62] P. Fitzgerald,et al. Molecular replacement , 1992 .
[63] A. Brunger. Free R value: a novel statistical quantity for assessing the accuracy of crystal structures. , 1992 .
[64] P. Ingham,et al. Role of the Drosophila patched gene in positional signalling , 1991, Nature.
[65] J. Zou,et al. Improved methods for building protein models in electron density maps and the location of errors in these models. , 1991, Acta crystallographica. Section A, Foundations of crystallography.
[66] C. Chothia,et al. The structure of protein-protein recognition sites. , 1990, The Journal of biological chemistry.
[67] K. Kroll,et al. Cloning and characterization of the segment polarity gene cubitus interruptus Dominant of Drosophila. , 1990, Genes & development.
[68] David Hogg,et al. Mutations in SUFU predispose to medulloblastoma , 2002, Nature Genetics.
[69] G. Bricogne,et al. [27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods. , 1997, Methods in enzymology.
[70] Z. Otwinowski,et al. Processing of X-ray diffraction data collected in oscillation mode. , 1997, Methods in enzymology.
[71] J. Abrahams,et al. Methods used in the structure determination of bovine mitochondrial F1 ATPase. , 1996, Acta crystallographica. Section D, Biological crystallography.
[72] A. Brünger. Free R value: a novel statistical quantity for assessing the accuracy of crystal structures , 1992, Nature.