Identification of N-(5-tert-butyl-isoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea dihydrochloride (AC220), a uniquely potent, selective, and efficacious FMS-like tyrosine kinase-3 (FLT3) inhibitor.
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P. Zarrinkar | H. Patel | T. Carter | R. Grotzfeld | Andiliy G. Lai | A. Velasco | R. Gunawardane | Merryl D. Cramer | Q. Chao | K. Sprankle | J. James | S. Bhagwat | M. Gardner