5597 Background: To investigate molecular imaging of cervix cancer with combined multiparametric positron emission tomography - magnetic resonance imaging (3T MP PET-MRI) using multiple MRI techniques and PET tracers for an improved understanding of tumor biology and heterogeneity. Methods: Ten patients with cervix cancer scheduled for radiation therapy were included in this IRB-approved prospective study. All patients were examined with combined 3T MP PET-MRI. The MRI protocol consisted of a high-resolution T2-weighted, a diffusion-weighted and a T1-weighted sequence with fat-sat before and after the application of contrast agent. All patients underwent 18F-FDG/18F-FMISO PET/CT. Patients were injected with approximately 330 MBq 18F-FDG and 18F-FMISO on different days and scanning was started 45 min after injection of 18F-FDG and 180 min after injection of 18F-FMISO. PET and MR image registrations were performed using Mirada RTx (Mirada Medical, Oxford, UK , ver. 1.4.0.23) software. 3T MP PET-MRI was asse...