Prevention of carbohydrate-mediated clearance of ricin-containing immunotoxins by the liver.

[1]  D. Blakey,et al.  Effect of chemical deglycosylation of ricin A chain on the in vivo fate and cytotoxic activity of an immunotoxin composed of ricin A chain and anti-Thy 1.1 antibody. , 1987, Cancer research.

[2]  D. Blakey,et al.  The preparation of deglycosylated ricin by recombination of glycosidase-treated A- and B-chains: effects of deglycosylation on toxicity and in vivo distribution. , 1987, Biochimica et biophysica acta.

[3]  W. Ross,et al.  Effect of linkage variation on pharmacokinetics of ricin A chain-antibody conjugates in normal rats. , 1986, Anti-cancer drug design.

[4]  P. Thorpe,et al.  Enzymic removal of two oligosaccharide chains from ricin B‐chain , 1986, FEBS letters.

[5]  J. Russell,et al.  Mannose receptor-mediated uptake of ricin toxin and ricin A chain by macrophages. Multiple intracellular pathways for a chain translocation. , 1986, The Journal of biological chemistry.

[6]  R. J. Price,et al.  Mannose receptor dependent uptake of a ricin A chain--antibody conjugate by rat liver non-parenchymal cells. , 1986, Biochemical and biophysical research communications.

[7]  R. Hill,et al.  The binding of fucose-containing glycoproteins by hepatic lectins. Purification of a fucose-binding lectin from rat liver. , 1986, The Journal of biological chemistry.

[8]  R. Hill,et al.  The binding of fucose-containing glycoproteins by hepatic lectins. The binding specificity of the rat liver fucose lectin. , 1986, The Journal of biological chemistry.

[9]  S. Pizzo,et al.  The binding of fucose-containing glycoproteins by hepatic lectins. Re-examination of the clearance from blood and the binding to membrane receptors and pure lectins. , 1986, The Journal of biological chemistry.

[10]  B. Foxwell,et al.  Selective uptake of ricin A‐chain by hepatic non‐parenchymal cells in vitro , 1986, FEBS letters.

[11]  W. Ross,et al.  Fate of an antibody-ricin A chain conjugate administered to normal rats. , 1986, Biochemical pharmacology.

[12]  P. Casellas,et al.  Study of the plasma clearance of antibody--ricin-A-chain immunotoxins. Evidence for specific recognition sites on the A chain that mediate rapid clearance of the immunotoxin. , 1986, European journal of biochemistry.

[13]  D. Blakey,et al.  Effect of chemical deglycosylation on the in vivo fate of ricin A-chain. , 1986, Cancer drug delivery.

[14]  R. J. Price,et al.  Modification of the carbohydrate in ricin with metaperiodate and cyanoborohydride mixtures: effect on binding, uptake and toxicity to parenchymal and non-parenchymal cells of rat liver. , 1985, Biochimica et biophysica acta.

[15]  B. Foxwell,et al.  The removal of carbohydrates from ricin with endoglycosidases H, F and D and α-mannosidase , 1985 .

[16]  L. Roberts,et al.  Nucleotide sequence of cloned cDNA coding for preproricin. , 1985, European journal of biochemistry.

[17]  F. Stirpe,et al.  Modification of the carbohydrate in ricin with metaperiodate-cyanoborohydride mixtures. Effects on toxicity and in vivo distribution. , 1985, European journal of biochemistry.

[18]  J. L. Bodmer.  Membrane receptors for particles and opsonins , 1985 .

[19]  R. Dean,et al.  Mononuclear phagocytes : physiology and pathology , 1985 .

[20]  E. Vitetta,et al.  Immunotoxins containing ricin A or B chains with modified carbohydrate residues act synergistically in killing neoplastic B cells in vitro. , 1985, Cancer drug delivery.

[21]  J. Uhr,et al.  Cytotoxicity of a cell-reactive immunotoxin containing ricin A chain is potentiated by an anti-immunotoxin containing ricin B chain , 1984, The Journal of experimental medicine.

[22]  P. Casellas,et al.  Significance of the Kinetics of Immunotoxin Cytotoxicity , 1984 .

[23]  V. Raso,et al.  Study of the Transferrin Receptor Using a Cytotoxic Human Transferrin-Ricin a Chain Conjugate , 1984 .

[24]  G. Poste,et al.  Receptor-Mediated Targeting of Drugs , 1984, Springer US.

[25]  D. C. Edwards,et al.  Ricin B chain converts a non‐cytotoxic antibody‐ricin A chain conjugate into a potent and specific cytotoxic agent , 1983, FEBS Letters.

[26]  J. Uhr,et al.  Synergy of ricin A chain-containing immunotoxins and ricin B chain-containing immunotoxins in in vitro killing of neoplastic human B cells. , 1983, Proceedings of the National Academy of Sciences of the United States of America.

[27]  F. Stirpe,et al.  A comparison of the accumulation of ricin by hepatic parenchymal and non-parenchymal cells and its inhibition of protein synthesis. , 1981, Biochimica et biophysica acta.

[28]  Y. Maynard,et al.  Oligosaccharide specific endocytosis by isolated rat hepatic reticuloendothelial cells. , 1981, The Journal of biological chemistry.

[29]  P. Schlesinger,et al.  L-Fucose-terminated glycoconjugates are recognized by pinocytosis receptors on macrophages. , 1981, Proceedings of the National Academy of Sciences of the United States of America.

[30]  F. Schaffner.  The reticuloendothelial system and the pathogenesis of liver disease , 1981 .

[31]  N. Kaplan,et al.  On the role of the covalent carbohydrate in the action of ricin. , 1980, The Journal of biological chemistry.

[32]  P. Schlesinger,et al.  The role of extra-hepatic tissues in the receptor-mediated plasma clearance of glycoproteins terminated by mannose or N-acetylglucosamine. , 1980, The Biochemical journal.

[33]  R. Brady,et al.  Fucose plays a role in the clearance and uptake of glucocerebrosidase by rat liver cells. , 1980, Biochemical and biophysical research communications.

[34]  J. Baynes,et al.  Carbohydrate-mediated clearance of immune complexes from the circulation. A role for galactose residues in the hepatic uptake of IgG-antigen complexes. , 1980, The Journal of biological chemistry.

[35]  J. Baynes,et al.  Carbohydrate-mediated clearance of antibody . antigen complexes from the circulation. The role of high mannose oligosaccharides in the hepatic uptake of IgM . antigen complexes. , 1980, The Journal of biological chemistry.

[36]  D. Bainton,et al.  Properties of Kupffer Cells , 1980 .

[37]  A. Magee,et al.  Identification of a defence mechanism in vivo against the leakage of enterokinase into the blood. , 1979, The Biochemical journal.

[38]  G. Wilson,et al.  An electron microscope autoradiographic study of the carbohydrate recognition systems in rat liver. I. Distribution of 125I-ligands among the liver cell types , 1979, The Journal of cell biology.

[39]  D. Dearborn,et al.  Labeling of proteins by reductive methylation using sodium cyanoborohydride. , 1979, The Journal of biological chemistry.

[40]  C. Steer,et al.  Unique distribution of glycoprotein receptors on parenchymal and sinusoidal cells of rat liver. , 1979, The Journal of biological chemistry.

[41]  P. Schlesinger,et al.  Plasma clearance of glycoproteins with terminal mannose and N-acetylglucosamine by liver non-parenchymal cells. Studies with beta-glucuronidase, N-acetyl-beta-D-glucosaminidase, ribonuclease B and agalacto-orosomucoid. , 1978, The Biochemical journal.

[42]  W. Sly,et al.  Inhibition of the rat clearance system for agalacto-orosomucoid by yeast mannans and by mannose. , 1977, Biochemical and biophysical research communications.

[43]  M. Friedman,et al.  Factors affecting cyanoborohydride reduction of aromatic Schiff's bases in proteins. , 1977, Advances in experimental medicine and biology.

[44]  P. Schlesinger,et al.  Clearance of lysosomal hydrolases following intravenous infusion: The role of liver in the clearance of β-glucuronidase and N-acetyl-β-d-glucosaminidase , 1976 .

[45]  F. Stirpe,et al.  Toxic effects of ricin: studies on the pathogenesis of liver lesions. , 1976, Virchows Archiv. B, Cell pathology.

[46]  A. Morell,et al.  The role of surface carbohydrates in the hepatic recognition and transport of circulating glycoproteins. , 2006, Advances in enzymology and related areas of molecular biology.

[47]  A. Gottschalk.  Glycoproteins: Their composition, structure and function , 1972 .

[48]  M. Ishiguro,et al.  Structure and Toxic Function of Ricin II:Subunit Structure of Ricin D , 1971 .

[49]  J. Clamp,et al.  THE PERIODATE OXIDATION OF AMINO ACIDS WITH REFERENCE TO STUDIES ON GLYCOPROTEINS. , 1965, The Biochemical journal.