CD40-CD40 ligand: a multifunctional receptor-ligand pair.

[1]  J. Banchereau,et al.  Bcl-2+ tonsillar plasma cells are rescued from apoptosis by bone marrow fibroblasts , 1996, The Journal of experimental medicine.

[2]  J. Banchereau,et al.  CD40 and B cell antigen receptor dual triggering of resting B lymphocytes turns on a partial germinal center phenotype , 1996, The Journal of experimental medicine.

[3]  P. Krammer,et al.  CD40 ligation induces Apo-1/Fas expression on human B lymphocytes and facilitates apoptosis through the Apo-1/Fas pathway , 1995, The Journal of experimental medicine.

[4]  J. Banchereau,et al.  Fas ligation induces apoptosis of CD40-activated human B lymphocytes , 1995, The Journal of experimental medicine.

[5]  J. Banchereau,et al.  Long-term cultured CD40-activated B lymphocytes differentiate into plasma cells in response to IL-10 but not IL-4. , 1995, International immunology.

[6]  J. Banchereau,et al.  CD40-activated human naive surface IgD+ B cells produce IgG2 in response to activated T-cell supernatant. , 1995, Immunology.

[7]  P. Kiener,et al.  Expression of functional CD40 by vascular endothelial cells , 1995, The Journal of experimental medicine.

[8]  L. Notarangelo,et al.  Immunohistologic analysis of ineffective CD40-CD40 ligand interaction in lymphoid tissues from patients with X-linked immunodeficiency with hyper-IgM. Abortive germinal center cell reaction and severe depletion of follicular dendritic cells. , 1995, Journal of immunology.

[9]  F. Rieux-Laucat,et al.  Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity. , 1995, Science.

[10]  A. Lanzavecchia,et al.  CD40 ligand‐independent B cell activation revealed by CD40 ligand‐deficient T cell clones: evidence for distinct activation requirements for antibody formation and B cell proliferation , 1995, European journal of immunology.

[11]  R. Kroczek,et al.  A soluble form of TRAP (CD40 ligand) is rapidly released after T cell activation , 1995, European journal of immunology.

[12]  P. Krammer,et al.  Regulation of germinal center B cell differentiation. Role of the human APO-1/Fas (CD95) molecule. , 1995, Journal of immunology.

[13]  A. Lakeman,et al.  Follicular dendritic cells inhibit apoptosis in human B lymphocytes by a rapid and irreversible blockade of preexisting endonuclease , 1995, The Journal of experimental medicine.

[14]  K. Shokat,et al.  Antigen-induced B-cell death and elimination during germinal-centre immune responses , 1995, Nature.

[15]  Kenneth G. C. Smith,et al.  Soluble antigen can cause enhanced apoptosis of germinal-centre B cells , 1995, Nature.

[16]  Arul M. Chinnaiyan,et al.  FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis , 1995, Cell.

[17]  P. Leder,et al.  RIP: A novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death , 1995, Cell.

[18]  D. Goeddel,et al.  The TNF receptor 1-associated protein TRADD signals cell death and NF-κB activation , 1995, Cell.

[19]  J. Cleveland,et al.  Contenders in FasL/TNF death signaling , 1995, Cell.

[20]  L. Davis,et al.  The CD40 ligand expressed by human B cells costimulates B cell responses. , 1995, Journal of immunology.

[21]  J. Pober,et al.  CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[22]  J. Banchereau,et al.  Generation of memory B cells and plasma cells in vitro , 1995, Science.

[23]  H. P. Fell,et al.  Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells. , 1995, Immunity.

[24]  C. Thompson,et al.  The role of bcl‐xL in CD40‐mediated rescue from anti‐μ‐induced apoptosis in WEHI‐231 B lymphoma cells , 1995, European journal of immunology.

[25]  M. Aguet,et al.  CD40 ligand has potent antiviral activity , 1995, Nature Medicine.

[26]  John Calvin Reed,et al.  FAP-1: a protein tyrosine phosphatase that associates with Fas. , 1995, Science.

[27]  Liangji Zhou,et al.  Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily. , 1995, Journal of immunology.

[28]  T. Yokota,et al.  Expression of the Fas ligand in cells of T cell lineage. , 1995, Journal of immunology.

[29]  T. Taniguchi Cytokine signaling through nonreceptor protein tyrosine kinases. , 1995, Science.

[30]  J. Camonis,et al.  A Novel Protein That Interacts with the Death Domain of Fas/APO1 Contains a Sequence Motif Related to the Death Domain (*) , 1995, The Journal of Biological Chemistry.

[31]  K. Anderson,et al.  CD40 ligand triggered interleukin-6 secretion in multiple myeloma. , 1995, Blood.

[32]  J. Banchereau,et al.  T cell-induced B cell blasts differentiate into plasma cells when cultured on bone marrow stroma with IL-3 and IL-10. , 1995, International immunology.

[33]  F. Fitch,et al.  IL-4-producing CD8+ T cell clones can provide B cell help. , 1995, Journal of immunology.

[34]  C. Maliszewski,et al.  Activated T cells induce interleukin‐12 production by monocytes via CD40‐CD40 ligand interaction , 1995, European journal of immunology.

[35]  M. Alderson,et al.  B-cell stimulation. , 1995, Current opinion in immunology.

[36]  N. Copeland,et al.  Gene structure and chromosomal localization of the mouse homologue of rat OX40 protein , 1995, European journal of immunology.

[37]  I. Maclennan,et al.  A subset of CD4+ memory T cells contains preformed CD40 ligand that is rapidly but transiently expressed on their surface after activation through the T cell receptor complex , 1995, The Journal of experimental medicine.

[38]  A. Durandy,et al.  Recombinant Soluble Trimeric CD40 Ligand Is Biologically Active * , 1995, The Journal of Biological Chemistry.

[39]  F. Alt,et al.  Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene , 1995, Nature.

[40]  K. Rajewsky,et al.  Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav , 1995, Nature.

[41]  J. Banchereau,et al.  Endogenous IL-6 and IL-10 contribute to the differentiation of CD40-activated human B lymphocytes. , 1995, Journal of immunology.

[42]  G. Fiucci,et al.  Three functional soluble forms of the human apoptosis-inducing Fas molecule are produced by alternative splicing. , 1995, Journal of immunology.

[43]  P. Krammer,et al.  Identification of soluble APO-1 in supernatants of human B- and T-cell lines and increased serum levels in B- and T-cell leukemias. , 1995, Blood.

[44]  D. Baltimore,et al.  Involvement of CRAF1, a relative of TRAF, in CD40 signaling , 1995, Science.

[45]  S. Nagata,et al.  The Fas death factor , 1995, Science.

[46]  S. Ju,et al.  Protection against Fas-dependent Thl-mediated apoptosis by antigen receptor engagement in B cells , 1995, Nature.

[47]  J. Bonnefoy,et al.  CD40 ligand is functionally expressed on human eosinophils , 1995, European journal of immunology.

[48]  J. Banchereau,et al.  Anti‐CD40 plus interleukin‐4‐activated human naive B cell lines express unmutated immunoglobulin genes with intraclonal heavy chain isotype variability , 1995, European journal of immunology.

[49]  J. Banchereau,et al.  Memory B cells from human tonsils colonize mucosal epithelium and directly present antigen to T cells by rapid up-regulation of B7-1 and B7-2. , 1995, Immunity.

[50]  V. Bažil Physiological enzymatic cleavage of leukocyte membrane molecules. , 1995, Immunology today.

[51]  R. Geha,et al.  Somatic mutation of human immunoglobulin V genes in the X-linked HyperIgM syndrome. , 1995, The Journal of clinical investigation.

[52]  R. Geha,et al.  gamma/delta T lymphocytes express CD40 ligand and induce isotype switching in B lymphocytes , 1995, The Journal of experimental medicine.

[53]  A. Fischer,et al.  Undetectable CD40 ligand expression on T cells and low B cell responses to CD40 binding agonists in human newborns. , 1995, Journal of immunology.

[54]  J. von Kempis,et al.  ILA, the human 4-1BB homologue, is inducible in lymphoid and other cell lineages. , 1995, Blood.

[55]  C. Ware,et al.  The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family , 1995, Cell.

[56]  Wei Wei Wu,et al.  CD38 unresponsiveness of xid B cells implicates Bruton's tyrosine kinase (btk) as a regular of CD38 induced signal transduction. , 1995, International immunology.

[57]  J. Banchereau,et al.  Human circulating specific antibody‐forming cells after systemic and mucosal immunizations: differential homing commitments and cell surface differentiation markers , 1995, European journal of immunology.

[58]  P. Linsley,et al.  Studies on the interdependence of gp39 and B7 expression and function during antigen‐specific immune responses , 1995, European journal of immunology.

[59]  C. Mohan,et al.  Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis. , 1995, Journal of immunology.

[60]  J. Karras,et al.  Induction of the transcription factors NF-kappa B, AP-1 and NF-AT during B cell stimulation through the CD40 receptor. , 1995, International immunology.

[61]  J. Mountz,et al.  Characterization of human Fas gene. Exon/intron organization and promoter region. , 1995, Journal of immunology.

[62]  V. Zagonel,et al.  Expression of functional CD40 antigen on Reed-Sternberg cells and Hodgkin's disease cell lines. , 1995, Blood.

[63]  I. Matsuda,et al.  Signaling through CD40 rescues IgE but not IgG or IgA secretion in X-linked immunodeficiency with hyper-IgM. , 1995, The Journal of clinical investigation.

[64]  J. Banchereau,et al.  The ability of synoviocytes to support terminal differentiation of activated B cells may explain plasma cell accumulation in rheumatoid synovium. , 1995, The Journal of clinical investigation.

[65]  H. Hirai,et al.  An acute myeloid leukemia gene, AML1, regulates hemopoietic myeloid cell differentiation and transcriptional activation antagonistically by two alternative spliced forms. , 1995, The EMBO journal.

[66]  D. Lawrence,et al.  Activated T cells enhance nitric oxide production by murine splenic macrophages through gp39 and LFA‐1 , 1995, European journal of immunology.

[67]  G. Pizzolo,et al.  CD30, Th2 cytokines and HIV infection: a complex and fascinating link. , 1995, Immunology today.

[68]  H. Ochs,et al.  Diminished expression of CD40 ligand by activated neonatal T cells. , 1995, The Journal of clinical investigation.

[69]  F. Stirpe,et al.  CD30 (Ki-1) molecule: a new cytokine receptor of the tumor necrosis factor receptor superfamily as a tool for diagnosis and immunotherapy. , 1995, Blood.

[70]  F. Alt,et al.  CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[71]  M. Boguski,et al.  A novel RING finger protein interacts with the cytoplasmic domain of CD40. , 1994, The Journal of biological chemistry.

[72]  J. Suttles,et al.  Role of the CD40‐CD40 ligand interaction in CD4+ T cell contact‐dependent activation of monocyte interleukin‐1 synthesis , 1994, European journal of immunology.

[73]  M. Holman,et al.  Properties of mouse CD40. Ligation of CD40 activates B cells via a Ca++‐dependent, FK506‐sensitive pathway , 1994, European journal of immunology.

[74]  R. Geha,et al.  CD40 ligation induces lymphotoxin alpha gene expression in human B cells. , 1994, International immunology.

[75]  I. Behrmann,et al.  Structure of the human APO‐1 gene , 1994, European journal of immunology.

[76]  I. Berberich,et al.  Cross-linking CD40 on B cells rapidly activates nuclear factor-kappa B. , 1994, Journal of immunology.

[77]  M. Flajnik,et al.  Isolation of the Xenopus complement factor B complementary DNA and linkage of the gene to the frog MHC. , 1994, Journal of immunology.

[78]  J. Gribben,et al.  Pivotal role of the B7:CD28 pathway in transplantation tolerance and tumor immunity. , 1994, Blood.

[79]  S. Paulie,et al.  Antibodies to distinct epitopes on the CD40 molecule co-operate in stimulation and can be used for the detection of soluble CD40. , 1994, Immunology.

[80]  A. Tong,et al.  Anti-CD40 antibody binding modulates human multiple myeloma clonogenicity in vitro. , 1994, Blood.

[81]  J. Falkenburg,et al.  Proliferation and cytogenetic analysis of hairy cell leukemia upon stimulation via the CD40 antigen. , 1994, Blood.

[82]  A. Fischer,et al.  T cell clones from an X-linked hyper-immunoglobulin (IgM) patient induce IgE synthesis in vitro despite expression of nonfunctional CD40 ligand , 1994, The Journal of experimental medicine.

[83]  R J Armitage,et al.  Humoral immune responses in CD40 ligand-deficient mice , 1994, The Journal of experimental medicine.

[84]  R. Bataille,et al.  Expression of CD28 and CD40 in human myeloma cells: a comparative study with normal plasma cells. , 1994, Blood.

[85]  D. Hirschstein,et al.  Expression and function of CD40 on Hodgkin and Reed-Sternberg cells and the possible relevance for Hodgkin's disease , 1994 .

[86]  R. Callard,et al.  CD40 ligand (CD40L) expression and B cell function in agammaglobulinemia with normal or elevated levels of IgM (HIM). Comparison of X-linked, autosomal recessive, and non-X-linked forms of the disease, and obligate carriers. , 1994, Journal of immunology.

[87]  Y. S. Choi,et al.  Activation and proliferation of follicular dendritic cell-like cells by activated T lymphocytes. , 1994, Journal of immunology.

[88]  F. Ramsdell,et al.  Differential ability of Th1 and Th2 T cells to express Fas ligand and to undergo activation-induced cell death. , 1994, International immunology.

[89]  J. Inazawa,et al.  Human Fas ligand: gene structure, chromosomal location and species specificity. , 1994, International immunology.

[90]  D. Campana,et al.  Hyper IgM syndrome associated with defective CD40-mediated B cell activation. , 1994, The Journal of clinical investigation.

[91]  J. Banchereau,et al.  Activation of human dendritic cells through CD40 cross-linking , 1994, The Journal of experimental medicine.

[92]  T. Heike,et al.  Involvement of LFA-1/intracellular adhesion molecule-1-dependent cell adhesion in CD40-mediated inhibition of human B lymphoma cell death induced by surface IgM crosslinking. , 1994, Journal of immunology.

[93]  A. Aruffo,et al.  Antibody to the ligand of CD40, gp39, blocks the occurrence of the acute and chronic forms of graft-vs-host disease. , 1994, The Journal of clinical investigation.

[94]  G. Sutherland,et al.  Moslecular and biological characterization of human 4‐1BB and its ligands , 1994, European journal of immunology.

[95]  M. Seldin,et al.  Molecular characterization of murine and human OX40/OX40 ligand systems: identification of a human OX40 ligand as the HTLV‐1‐regulated protein gp34. , 1994, The EMBO journal.

[96]  R. Noelle,et al.  The role of CD40 in the regulation of humoral and cell-mediated immunity. , 1994, Immunology today.

[97]  D. Goeddel,et al.  A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor , 1994, Cell.

[98]  R. Bast,et al.  Regulation of tumour necrosis factor-α processing by a metalloproteinase inhibitor , 1994, Nature.

[99]  A. H. Drummond,et al.  Processing of tumour necrosis factor-α precursor by metalloproteinases , 1994, Nature.

[100]  F. Haluska,et al.  The cellular biology of the Reed-Sternberg cell. , 1994, Blood.

[101]  R. Flavell,et al.  Mice deficient for the CD40 ligand. , 1994, Immunity.

[102]  L. Notarangelo,et al.  Ineffective expression of CD40 ligand on cord blood T cells may contribute to poor immunoglobulin production in the newborn , 1994, European journal of immunology.

[103]  P. Lipsky,et al.  The role of CD40-CD40 ligand interaction in human T cell-B cell collaboration. , 1994, Journal of immunology.

[104]  H. Stein,et al.  Hodgkin's disease with a B-cell phenotype often shows a VDJ rearrangement and somatic mutations in the VH genes. , 1994, Blood.

[105]  E. Engleman,et al.  Identification of a human OX-40 ligand, a costimulator of CD4+ T cells with homology to tumor necrosis factor , 1994, The Journal of experimental medicine.

[106]  M. Gerhart,et al.  Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing , 1994, Nature.

[107]  J. Strominger,et al.  Tumor necrosis factor alpha is an autocrine growth factor for normal human B cells. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[108]  M. Yellin,et al.  T lymphocyte T cell-B cell-activating molecule/CD40-L molecules induce normal B cells or chronic lymphocytic leukemia B cells to express CD80 (B7/BB-1) and enhance their costimulatory activity. , 1994, Journal of immunology.

[109]  E. Clark,et al.  The role of CD40 and CD80 accessory cell molecules in dendritic cell-dependent HIV-1 infection. , 1994, Immunity.

[110]  J. Banchereau,et al.  Localization of the human CD40 gene to chromosome 20, bands q12-q13.2. , 1994, Leukemia.

[111]  R. V. van Lier,et al.  CD27: marker and mediator of T-cell activation? , 1994, Immunology today.

[112]  D. Gray,et al.  Memory B cell development but not germinal center formation is impaired by in vivo blockade of CD40-CD40 ligand interaction , 1994, The Journal of experimental medicine.

[113]  R. Steinman,et al.  Proliferating dendritic cell progenitors in human blood , 1994, The Journal of experimental medicine.

[114]  R. Heller,et al.  Tumor necrosis factor receptor-mediated signaling pathways , 1994, The Journal of cell biology.

[115]  J. D. Capra,et al.  Analysis of somatic mutation in five B cell subsets of human tonsil , 1994, The Journal of experimental medicine.

[116]  A. Aruffo,et al.  gp39-CD40 interactions are essential for germinal center formation and the development of B cell memory , 1994, The Journal of experimental medicine.

[117]  H. Ochs,et al.  Costimulation through CD28 enhances T cell-dependent B cell activation via CD40-CD40L interaction. , 1994, Journal of immunology.

[118]  M. Toribio,et al.  Establishment and characterization of cloned human thymic epithelial cell lines. Analysis of adhesion molecule expression and cytokine production , 1994 .

[119]  R. Brines,et al.  Induction of NF-AT in normal B lymphocytes by anti-immunoglobulin or CD40 ligand in conjunction with IL-4. , 1994, Immunity.

[120]  N. Yoshida,et al.  The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation. , 1994, Immunity.

[121]  J. Parsons,et al.  CD40 signaling pathway: anti-CD40 monoclonal antibody induces rapid dephosphorylation and phosphorylation of tyrosine-phosphorylated proteins including protein tyrosine kinase Lyn, Fyn, and Syk and the appearance of a 28-kD tyrosine phosphorylated protein , 1994, The Journal of experimental medicine.

[122]  A. Aruffo,et al.  Signaling events during helper T cell-dependent B cell activation. I. Analysis of the signal transduction pathways triggered by activated helper T cell in resting B cells. , 1994, Journal of immunology.

[123]  D. Longo,et al.  Inhibition of human B-cell lymphoma growth by CD40 stimulation. , 1994, Blood.

[124]  P. Hodgkin,et al.  Anergic self-reactive B cells present self antigen and respond normally to CD40-dependent T-cell signals but are defective in antigen-receptor-mediated functions. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[125]  R. Kolesnick,et al.  The sphingomyelin pathway in tumor necrosis factor and interleukin-1 signaling , 1994, Cell.

[126]  F. Ramsdell,et al.  Recombinant CD40 ligand exerts potent biologic effects on T cells. , 1994, Journal of immunology.

[127]  M R Alderson,et al.  The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster. , 1994, Immunity.

[128]  Scott F. Smith,et al.  Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin. , 1994, Science.

[129]  C. Ware,et al.  A lymphotoxin-beta-specific receptor. , 1994, Science.

[130]  J. Bonnefoy,et al.  Prenatal diagnosis of X-linked hyper-IgM syndrome , 1994 .

[131]  H. Ochs,et al.  The Role of CD40 and its Ligand in the Regulation of the Immune Response , 1994, Immunological Reviews.

[132]  J. Banchereau,et al.  B cells regulate expression of CD40 ligand on activated T cells by lowering the mRNA level and through the release of soluble CD40 , 1994, European journal of immunology.

[133]  L. Notarangelo,et al.  Defective Expression of CD40 Ligand on T Cells Causes “X‐Linked Immunodeficiency with Hyper‐IgM (HIGM1)” , 1994, Immunological reviews.

[134]  F. Sallusto,et al.  Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha , 1994, The Journal of experimental medicine.

[135]  A. Lakeman,et al.  Functionally active Epstein-Barr virus-transformed follicular dendritic cell-like cell lines , 1994, The Journal of experimental medicine.

[136]  Matthew J. Brauer,et al.  Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule. , 1994, Science.

[137]  Terry Farrah,et al.  The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death , 1994, Cell.

[138]  N. Jenkins,et al.  Generalized lymphoproliferative disease in mice, caused by a point mutation in the fas ligand , 1994, Cell.

[139]  G. Klaus,et al.  Hypercross-linking surface IgM or IgD receptors on mature B cells induces apoptosis that is reversed by costimulation with IL-4 and anti-CD40. , 1994, Journal of immunology.

[140]  C. Patrosso,et al.  Organization of the human CD40L gene: implications for molecular defects in X chromosome-linked hyper-IgM syndrome and prenatal diagnosis. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[141]  G. Inghirami,et al.  T-BAM/CD40-L on helper T lymphocytes augments lymphokine-induced B cell Ig isotype switch recombination and rescues B cells from programmed cell death. , 1994, Journal of immunology.

[142]  J. Kwekkeboom,et al.  Helper effector function of human T cells stimulated by anti‐CD3 mAb can be enhanced by co‐stimulatory signals and is partially dependent on CD40‐CD40 ligand interaction , 1994, European journal of immunology.

[143]  B. Kwon,et al.  Genomic organization and chromosomal localization of the T-cell antigen 4-1BB. , 1994, Journal of immunology.

[144]  F. Ramsdell,et al.  CD40 ligand acts as a costimulatory signal for neonatal thymic gamma delta T cells. , 1994, Journal of immunology.

[145]  P. J. Belshaw,et al.  Cyclosporin A inhibits CD40 ligand expression in T lymphocytes. , 1994, The Journal of clinical investigation.

[146]  H. Stein,et al.  The human OX40 homolog: cDNA structure, expression and chromosomal assignment of the ACT35 antigen , 1994, European journal of immunology.

[147]  P. Lane,et al.  B cell function in mice transgenic for mCTLA4-H gamma 1: lack of germinal centers correlated with poor affinity maturation and class switching despite normal priming of CD4+ T cells , 1994, The Journal of experimental medicine.

[148]  J. Banchereau,et al.  Activated CD4+ T cells induce CD40-dependent proliferation of human B cell precursors. , 1994, Journal of immunology.

[149]  R. Kriz,et al.  The cloning of CD70 and its identification as the ligand for CD27. , 1994, Journal of immunology.

[150]  Jeffrey A. Ledbetter,et al.  How B and T cells talk to each other , 1994, Nature.

[151]  H. Ochs,et al.  CD40 ligand expression is defective in a subset of patients with common variable immunodeficiency. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[152]  P. Linsley,et al.  Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells , 1994, The Journal of experimental medicine.

[153]  J. Banchereau,et al.  Human interleukin 10 induces naive surface immunoglobulin D+ (sIgD+) B cells to secrete IgG1 and IgG3 , 1994, The Journal of experimental medicine.

[154]  R. Geha,et al.  Signal transduction via CD40 involves activation of lyn kinase and phosphatidylinositol-3-kinase, and phosphorylation of phospholipase C gamma 2 , 1994, The Journal of experimental medicine.

[155]  P. Lipsky,et al.  Ligation of CD40 induces sterile transcripts of multiple Ig H chain isotypes in human B cells. , 1994, Journal of immunology.

[156]  G. Klaus,et al.  B cells from CBA/N mice do not proliferate following ligation of CD40 , 1994, European journal of immunology.

[157]  R. Noelle,et al.  The CD40/CD40L interaction — all things to all immunologists , 1994 .

[158]  G. Ahmann,et al.  CD40 expression in malignant plasma cells. Role in stimulation of autocrine IL-6 secretion by a human myeloma cell line. , 1994, Journal of immunology.

[159]  S. Howie,et al.  CD40 expression in Hodgkin's disease. , 1994, The American journal of pathology.

[160]  J. Banchereau,et al.  The CD40 antigen and its ligand. , 1994, Annual review of immunology.

[161]  J. Banchereau,et al.  CD40-activated surface IgD-positive lymphocytes constitute the long term IL-4-dependent proliferating B cell pool. , 1994, Journal of immunology.

[162]  Takashi Suda,et al.  Molecular cloning and expression of the fas ligand, a novel member of the tumor necrosis factor family , 1993, Cell.

[163]  M. Lotz,et al.  A receptor induced by lymphocyte activation (ILA): a new member of the human nerve-growth-factor/tumor-necrosis-factor receptor family. , 1993, Gene.

[164]  J. Ceuppens,et al.  Ligation of B7 with CD28/CTLA‐4 on T cells results in CD40 ligand expression, interleukin‐4 secretion and efficient help for antibody production by B cells , 1993, European journal of immunology.

[165]  H. P. Fell,et al.  Cloning of mouse Ox40: a T cell activation marker that may mediate T-B cell interactions. , 1993, Journal of immunology.

[166]  G. Aversa,et al.  Human pre-B cells differentiate into Ig-secreting plasma cells in the presence of interleukin-4 and activated CD4+ T cells or their membranes , 1993 .

[167]  R. Callard,et al.  CD40 ligand and its role in X-linked hyper-IgM syndrome. , 1993, Immunology today.

[168]  J. Banchereau,et al.  Interleukin 10 (IL-10) upregulates functional high affinity IL-2 receptors on normal and leukemic B lymphocytes , 1993, The Journal of experimental medicine.

[169]  A. Aruffo,et al.  In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions , 1993, The Journal of experimental medicine.

[170]  A. Aruffo,et al.  In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39 , 1993, The Journal of experimental medicine.

[171]  D. Golde,et al.  Soluble hormone receptors. , 1993, Blood.

[172]  J. Gordon,et al.  Protein tyrosine phosphorylation is mandatory for CD40‐mediated rescue of germinal center B cells from apoptosis , 1993, European journal of immunology.

[173]  N. Copeland,et al.  Molecular cloning of a ligand for the inducible T cell gene 4‐1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor , 1993, European journal of immunology.

[174]  T. Defrance,et al.  Phenotypic and functional heterogeneity of the IgD- B cell compartment: identification of two major tonsillar B cell subsets. , 1993, International immunology.

[175]  K. Kishi,et al.  Induction of human IgE synthesis in B cells by mast cells and basophils , 1993, Nature.

[176]  T. Lister,et al.  Isolated follicular lymphoma cells are resistant to apoptosis and can be grown in vitro in the CD40/stromal cell system. , 1993, Blood.

[177]  A. Aruffo,et al.  Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40. , 1993, Science.

[178]  J. Bazan Emerging families of cytokines and receptors , 1993, Current Biology.

[179]  M. Milili,et al.  Induction by anti‐CD40 antibody or soluble CD40 ligand and cytokines of IgG, IgA and IgE production by B cells from patients with X‐linked hyper IgM syndrome , 1993, European journal of immunology.

[180]  D. Catovsky,et al.  In vitro activation of leukaemic B cells by interleukin-4 and antibodies to CD40. , 1993, Immunology.

[181]  F. Ramsdell,et al.  CD40 ligand is a T cell growth factor , 1993, European journal of immunology.

[182]  A. Aruffo,et al.  The regulation of the expression of gp39, the CD40 ligand, on normal and cloned CD4+ T cells. , 1993, Journal of immunology.

[183]  I. Maclennan,et al.  Suppression of apoptosis in normal and neoplastic human B lymphocytes by CD40 ligand is independent of Bcl‐2 induction , 1993, European journal of immunology.

[184]  L. Castagnoli,et al.  Regulation of expression of the ligand for CD40 on T helper lymphocytes. , 1993, Journal of immunology.

[185]  C. Berek,et al.  The maturation of the immune response. , 1993, Immunology today.

[186]  Jing Wu,et al.  B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40 , 1993, Nature.

[187]  W. Fanslow,et al.  CD40 expression by human monocytes: regulation by cytokines and activation of monocytes by the ligand for CD40 , 1993, The Journal of experimental medicine.

[188]  N. Copeland,et al.  CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF , 1993, Cell.

[189]  R. Geha,et al.  Deletions in the ligand for CD40 in X-linked immunoglobulin deficiency with normal or elevated IgM (HIGMX-1). , 1993, International immunology.

[190]  K. Bacon,et al.  Anti-CD40 antibody stimulates the VLA-4-dependent adhesion of normal and LFA-1-deficient B cells to endothelium. , 1993, Immunology.

[191]  J. Banchereau,et al.  Human B cell precursors proliferate and express CD23 after CD40 ligation , 1993, The Journal of experimental medicine.

[192]  E. Maggi,et al.  Membrane tumour necrosis factor-α is involved in the polyclonal B-cell activation induced by HIV-infected human T cells , 1993, Nature.

[193]  G. Aversa,et al.  The 26-kD transmembrane form of tumor necrosis factor alpha on activated CD4+ T cell clones provides a costimulatory signal for human B cell activation , 1993, The Journal of experimental medicine.

[194]  R. de Waal Malefyt,et al.  IL-13 induces proliferation and differentiation of human B cells activated by the CD40 ligand. , 1993, International immunology.

[195]  S. Nagata,et al.  A novel protein domain required for apoptosis. Mutational analysis of human Fas antigen. , 1993, The Journal of biological chemistry.

[196]  A. Abbas,et al.  Analysis of IL-2, IL-4, and IFN-gamma-producing cells in situ during immune responses to protein antigens. , 1993, Journal of immunology.

[197]  D. Banner,et al.  Crystal structure of the soluble human 55 kd TNF receptor-human TNFβ complex: Implications for TNF receptor activation , 1993, Cell.

[198]  G. Sutherland,et al.  Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor , 1993, Cell.

[199]  J. Gusella,et al.  Chromosomal localization of the gene for human B-cell antigen CD40 , 1993, Somatic cell and molecular genetics.

[200]  W. Fanslow,et al.  Human B cell proliferation and Ig secretion induced by recombinant CD40 ligand are modulated by soluble cytokines. , 1993, Journal of immunology.

[201]  C. Maliszewski,et al.  Recombinant CD40 ligand stimulation of murine B cell growth and differentiation: cooperative effects of cytokines , 1993, European journal of immunology.

[202]  Mike Rothe,et al.  Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptor , 1993, Cell.

[203]  C. Maliszewski,et al.  The regulation of T cell-dependent antibody formation in vitro by CD40 ligand and IL-2. , 1993, Journal of immunology.

[204]  R. de Waal Malefyt,et al.  Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[205]  R. de Waal Malefyt,et al.  Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[206]  P. Möller,et al.  Coregulation of the APO-1 antigen with intercellular adhesion molecule-1 (CD54) in tonsillar B cells and coordinate expression in follicular center B cells and in follicle center and mediastinal B-cell lymphomas. , 1993, Blood.

[207]  T. Chiles,et al.  T cell-dependent induction of NF-kappa B in B cells , 1993, The Journal of experimental medicine.

[208]  P. Marynen,et al.  Construction and evaluation of a hncDNA library of human 12p transcribed sequences derived from a somatic cell hybrid. , 1993, Genomics.

[209]  B. Blom,et al.  Cloning and expression of murine CD27: comparison with 4‐1BB, another lymphocyte‐specific member of the nerve growth factor receptor family , 1993, European journal of immunology.

[210]  J. Banchereau,et al.  Expression of a 32‐kDa ligand for the CD40 antigen on activated human T lymphocytes , 1993, European journal of immunology.

[211]  T. Kipps,et al.  Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signal , 1993, The Journal of experimental medicine.

[212]  Carl F. Ware,et al.  Lymphotoxin β, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface , 1993, Cell.

[213]  P. Casellas,et al.  lnterleukin-13 is a new human lymphokine regulating inflammatory and immune responses , 1993, Nature.

[214]  S. Shchelkunov,et al.  Genes of variola and vaccinia viruses necessary to overcome the host protective mechanisms , 1993, FEBS letters.

[215]  I. Stamenkovic,et al.  Defective expression of the CD40 ligand in X chromosome-linked immunoglobulin deficiency with normal or elevated IgM. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[216]  J. Banchereau,et al.  Culture of human fetal B-cell precursors on bone marrow stroma maintains highly proliferative CD20dim cells. , 1993, Blood.

[217]  G. Van den Ackerveken,et al.  Characterization of two putative pathogenicity genes of the fungal tomato pathogen Cladosporium fulvum. , 1993, Molecular plant-microbe interactions : MPMI.

[218]  J. Belmont,et al.  CD40 ligand gene defects responsible for X-linked hyper-IgM syndrome , 1993, Science.

[219]  A. Fischer,et al.  CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM , 1993, Nature.

[220]  L. Notarangelo,et al.  Defective expression of T-cell CD40 ligand causes X-linked immunodeficiency with hyper-IgM , 1993, Nature.

[221]  H. Chapel,et al.  The fruits of cooperation , 1993, Nature.

[222]  M C Peitsch,et al.  A 3-D model for the CD40 ligand predicts that it is a compact trimer similar to the tumor necrosis factors. , 1993, International immunology.

[223]  J. Banchereau,et al.  Epstein-Barr virus transformation induces B lymphocytes to produce human interleukin 10 , 1993, The Journal of experimental medicine.

[224]  J. Bajorath,et al.  The CD40 ligand, gp39, is defective in activated T cells from patients with X-linked hyper-IgM syndrome , 1993, Cell.

[225]  J. Bonnefoy,et al.  Human CD40‐ligand: molecular cloning, cellular distribution and regulation of expression by factors controlling IgE production , 1993, FEBS letters.

[226]  M. Bowen Functional characterization of CD30 on the large granular lymphoma cell line YT, and the cloning of a murine CD30cDNA homologue , 1993 .

[227]  R. Bradshaw,et al.  The receptors for nerve growth factor and other neurotrophins. , 1993, Annual review of biochemistry.

[228]  D. Parker T cell-dependent B cell activation. , 1993, Annual review of immunology.

[229]  A. Butch,et al.  Cytokine expression by germinal center cells. , 1993, Journal of immunology.

[230]  R. Schwartz Costimulation of T lymphocytes: the role of CD28, CTLA-4, and B7/BB1 in interleukin-2 production and immunotherapy , 1992, Cell.

[231]  D. Cockayne,et al.  Genomic structure and chromosomal mapping of the murine CD40 gene. , 1992, Journal of immunology.

[232]  A. Hagemeijer,et al.  Genomic organization and chromosomal localization of the human CD27 gene. , 1992, Journal of immunology.

[233]  G. Inghirami,et al.  Molecular interactions mediating T-B lymphocyte collaboration in human lymphoid follicles. Roles of T cell-B-cell-activating molecule (5c8 antigen) and CD40 in contact-dependent help. , 1992, Journal of immunology.

[234]  J. Banchereau,et al.  Responsiveness of chronic lymphocytic leukemia B cells activated via surface Igs or CD40 to B-cell tropic factors. , 1992, Blood.

[235]  M. Valentine,et al.  Rescue from anti‐IgM‐induced programmed cell death by the B cell surface proteins CD20 and CD40 , 1992, European journal of immunology.

[236]  I. Stamenkovic,et al.  The human T cell antigen gp39, a member of the TNF gene family, is a ligand for the CD40 receptor: expression of a soluble form of gp39 with B cell co‐stimulatory activity. , 1992, The EMBO journal.

[237]  H. Mages,et al.  Cloning of TRAP, a ligand for CD40 on human T cells , 1992, European journal of immunology.

[238]  C. Maliszewski,et al.  Recombinant human CD40 ligand stimulates B cell proliferation and immunoglobulin E secretion , 1992, The Journal of experimental medicine.

[239]  J. Banchereau,et al.  GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells , 1992, Nature.

[240]  J. Inazawa,et al.  Assignment of the human Fas antigen gene (Fas) to 10q24.1. , 1992, Genomics.

[241]  H. Stein,et al.  Assignment of the human CD30 (Ki-1) gene to 1p36. , 1992, Genomics.

[242]  J. Banchereau,et al.  Proliferation and differentiation of human CD5+ and CD5− B cell subsets activated through their antigen receptors or CD40 antigens , 1992, European journal of immunology.

[243]  R. Peach,et al.  T-cell activation molecule 4-1BB binds to extracellular matrix proteins. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[244]  L. Gooding Virus proteins that counteract host immune defenses , 1992, Cell.

[245]  N. Shastri Antigen processing and recognition Edited by James McCluskey. Boca Raton: CRC Press. (1991). 257 pp. $139.95 , 1992, Cell.

[246]  R. Levinsky,et al.  Mapping of the X-linked form of hyper-IgM syndrome (HIGM1) to Xq26 by close linkage to HPRT. , 1992, Genomics.

[247]  D. Gray,et al.  Activated human T cells express a ligand for the human B cell‐associated antigen CD40 which participates in T cell‐dependent activation of B lymphocytes , 1992, European journal of immunology.

[248]  P. Lichter,et al.  The human APO-1 (APT) antigen maps to 10q23, a region that is syntenic with mouse chromosome 19. , 1992, Genomics.

[249]  G. Kelsoe,et al.  In Situ Studies of the Primary Immune Response to ( 4-hydroxy-3-nitrophenyl ) acetyl . II . A Common Clonal Origin for Periarteriolar Lymphoid Sheath-associated Foci and Germinal Centers , 2003 .

[250]  C. Smith,et al.  Identification of a source of biologically active CD40 ligand , 1992, European journal of immunology.

[251]  H. Spits,et al.  CD40 is functionally expressed on human thymic epithelial cells. , 1992, Journal of immunology.

[252]  E. Clark,et al.  Soluble forms of CD40 inhibit biologic responses of human B cells. , 1992, Journal of immunology.

[253]  I. Stamenkovic,et al.  A 39-kDa protein on activated helper T cells binds CD40 and transduces the signal for cognate activation of B cells. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[254]  T. Farrah,et al.  Emerging cytokine family , 1992, Nature.

[255]  E. Clark,et al.  Cultured human follicular dendritic cells. Growth characteristics and interactions with B lymphocytes. , 1992, Journal of immunology.

[256]  M. Pawlita,et al.  Purification and molecular cloning of the APO-1 cell surface antigen, a member of the tumor necrosis factor/nerve growth factor receptor superfamily. Sequence identity with the Fas antigen. , 1992, The Journal of biological chemistry.

[257]  E. Clark,et al.  Molecular and biological characterization of a murine ligand for CD40 , 1992, Nature.

[258]  P. Ambros,et al.  Structure of the human TNF receptor 1 (p60) gene (TNRF1) and localization to chromosome 12p13 , 1992 .

[259]  Tom L. Blundell,et al.  Disruption of the low affinity receptor-binding site in NGF allows neuronal survival and differentiation by binding to the trk gene product , 1992, Cell.

[260]  S. Lederman,et al.  Identification of a novel surface protein on activated CD4+ T cells that induces contact-dependent B cell differentiation (help) , 1992, The Journal of experimental medicine.

[261]  N. Copeland,et al.  Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis , 1992, Nature.

[262]  J. Banchereau,et al.  Interleukin 10 is a potent growth and differentiation factor for activated human B lymphocytes. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[263]  J. Banchereau,et al.  Interleukin 10 and transforming growth factor beta cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A , 1992, The Journal of experimental medicine.

[264]  N. Copeland,et al.  The cDNA structure, expression, and chromosomal assignment of the mouse Fas antigen. , 1992, Journal of immunology.

[265]  H. Stein,et al.  Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease , 1992, Cell.

[266]  S R Sprang,et al.  The structure of human lymphotoxin (tumor necrosis factor-beta) at 1.9-A resolution. , 1992, The Journal of biological chemistry.

[267]  R. V. van Lier,et al.  The CD27 membrane receptor, a lymphocyte‐specific member of the nerve growth factor receptor family, gives rise to a soluble form by protein processing that does not involve receptor endocytosis , 1992, European journal of immunology.

[268]  E. Clark,et al.  Differential increase of an alternatively polyadenylated mRNA species of murine CD40 upon B lymphocyte activation. , 1992, Journal of immunology.

[269]  J. Banchereau,et al.  Human B lymphocytes: phenotype, proliferation, and differentiation. , 1992, Advances in immunology.

[270]  L. Notarangelo,et al.  Immunodeficiency with hyper-IgM (HIM). , 1992, Immunodeficiency reviews.

[271]  D. Stuart,et al.  Crystal structure of TNF. , 1992, Immunology series.

[272]  M. Conley,et al.  Molecular approaches to analysis of X-linked immunodeficiencies. , 1992, Annual review of immunology.

[273]  L. Tartaglia,et al.  Two TNF receptors. , 1992, Immunology today.

[274]  J. Banchereau,et al.  Distribution of surface-membrane molecules on bone marrow and cord blood CD34+ hematopoietic cells. , 1992, Experimental hematology.

[275]  A. Aruffo,et al.  CD40 and its ligand, an essential ligand-receptor pair for thymus-dependent B-cell activation. , 1992, Immunology today.

[276]  B. Aggarwal,et al.  Tumor necrosis factors. Structure, function, and mechanism of action. , 1992, Immunology series.

[277]  T. Tedder,et al.  Transmembrane signals generated through MHC class II, CD19, CD20, CD39, and CD40 antigens induce LFA-1-dependent and independent adhesion in human B cells through a tyrosine kinase-dependent pathway. , 1991, Journal of immunology.

[278]  C. Ware,et al.  Tumor necrosis factor (TNF) receptor expression in T lymphocytes. Differential regulation of the type I TNF receptor during activation of resting and effector T cells. , 1991, Journal of immunology.

[279]  L. Hammarström,et al.  TGF-β1 induces germ-line transcripts of both IgA subclasses in human B lymphocytes , 1991 .

[280]  J. C. Smith,et al.  Pre-Bötzinger complex: a brainstem region that may generate respiratory rhythm in mammals. , 1991, Science.

[281]  E. Roldán,et al.  Terminal differentiation of human bone marrow cells capable of spontaneous and high‐rate immunoglobulin secretion: Role of bone marrow stromal cells and interleukin 6 , 1991, European journal of immunology.

[282]  B. Seed,et al.  The T cell activation antigen CD27 is a member of the nerve growth factor/tumor necrosis factor receptor gene family. , 1991, Journal of immunology.

[283]  J. Banchereau,et al.  Growing human B lymphocytes in the CD40 system , 1991, Nature.

[284]  G. Schieven,et al.  Stimulation of protein tyrosine phosphorylation, phosphoinositide turnover, and multiple previously unidentified serine/threonine-specific protein kinases by the Pan-B-cell receptor CD40/Bp50 at discrete developmental stages of human B-cell ontogeny. , 1991, The Journal of biological chemistry.

[285]  G. McFadden,et al.  Myxoma virus expresses a secreted protein with homology to the tumor necrosis factor receptor gene family that contributes to viral virulence. , 1991, Virology.

[286]  Atsushi Hase,et al.  The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis , 1991, Cell.

[287]  I. T. Ten Berge,et al.  A soluble form of the human T cell differentiation antigen CD27 is released after triggering of the TCR/CD3 complex. , 1991, Journal of immunology.

[288]  A. Barclay,et al.  A new superfamily of cell surface proteins related to the nerve growth factor receptor. , 1991, Immunology today.

[289]  N. Copeland,et al.  Molecular cloning and expression of the type 1 and type 2 murine receptors for tumor necrosis factor , 1991, Molecular and cellular biology.

[290]  I. Franklin,et al.  Surface antigen expression of human neoplastic plasma cells includes molecules associated with lymphocyte recirculation and adhesion , 1991, British journal of haematology.

[291]  J. Vilček,et al.  Tumor necrosis factor. New insights into the molecular mechanisms of its multiple actions. , 1991, The Journal of biological chemistry.

[292]  G. McFadden,et al.  T2 open reading frame from the Shope fibroma virus encodes a soluble form of the TNF receptor. , 1991, Biochemical and biophysical research communications.

[293]  G. Wood,et al.  Expression, distribution, and biochemistry of human CD39. Role in activation-associated homotypic adhesion of lymphocytes. , 1991, Journal of immunology.

[294]  D. Pickup,et al.  Transcription of the terminal loop region of vaccinia virus DNA is initiated from the telomere sequences directing DNA resolution. , 1991, Virology.

[295]  E. Chen,et al.  Cloning and expression of cDNAs for two distinct murine tumor necrosis factor receptors demonstrate one receptor is species specific. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[296]  E. Clark,et al.  CD40 signaling activates CD11a/CD18 (LFA-1)-mediated adhesion in B cells. , 1991, Journal of immunology.

[297]  A. Saxon,et al.  CD40 stimulation provides an IFN-gamma-independent and IL-4-dependent differentiation signal directly to human B cells for IgE production. , 1991, Journal of immunology.

[298]  T. Gojobori,et al.  Molecular cloning and characterization of a novel glycoprotein, gp34, that is specifically induced by the human T-cell leukemia virus type I transactivator p40tax , 1991, Molecular and cellular biology.

[299]  J. Banchereau,et al.  Cytokine-induced proliferation and immunoglobulin production of human B lymphocytes triggered through their CD40 antigen , 1991, The Journal of experimental medicine.

[300]  Gwyn T. Williams,et al.  Activation of Epstein–Barr virus latent genes protects human B cells from death by apoptosis , 1991, Nature.

[301]  S. Paulie,et al.  Expression of CD40 and CD43 during Activation of Human B Lymphocytes , 1991, Scandinavian journal of immunology.

[302]  S. T. Howard,et al.  Vaccinia virus homologues of the Shope fibroma virus inverted terminal repeat proteins and a discontinuous ORF related to the tumor necrosis factor receptor family. , 1991, Virology.

[303]  D. Gray,et al.  Novel pathways of antigen presentation for the maintenance of memory. , 1991, International immunology.

[304]  J. Banchereau,et al.  Long-term human B cell lines dependent on interleukin-4 and antibody to CD40. , 1991, Science.

[305]  R. Steinman,et al.  The dendritic cell system and its role in immunogenicity. , 1991, Annual review of immunology.

[306]  J. Ledbetter,et al.  Temporal association of CD40 antigen expression with discrete stages of human B-cell ontogeny and the efficacy of anti-CD40 immunotoxins against clonogenic B-lineage acute lymphoblastic leukemia as well as B-lineage non-Hodgkin's lymphoma cells. , 1990, Blood.

[307]  R. Geha,et al.  CD40 and IgE: synergism between anti-CD40 monoclonal antibody and interleukin 4 in the induction of IgE synthesis by highly purified human B cells , 1990, The Journal of experimental medicine.

[308]  T. Lebien,et al.  Analysis of expression and function of CD40 on normal and leukemic human B cell precursors. , 1990, Leukemia.

[309]  R. Steinman,et al.  The distinct surface of human blood dendritic cells, as observed after an improved isolation method. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[310]  E. Clark,et al.  Association between IL-6 and CD40 signaling. IL-6 induces phosphorylation of CD40 receptors. , 1990, Journal of immunology.

[311]  H. Holtmann,et al.  Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity. , 1990, The Journal of biological chemistry.

[312]  I. Stamenkovic,et al.  Identification of the intracytoplasmic region essential for signal transduction through a B cell activation molecule, CD40 , 1990, European journal of immunology.

[313]  C. Nathan,et al.  Shedding of tumor necrosis factor receptors by activated human neutrophils , 1990, The Journal of experimental medicine.

[314]  C. Smith,et al.  A receptor for tumor necrosis factor defines an unusual family of cellular and viral proteins. , 1990, Science.

[315]  R. Coffman,et al.  Molecular characterization of germ-line immunoglobulin A transcripts produced during transforming growth factor type beta-induced isotype switching. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[316]  E. Kieff,et al.  Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23 , 1990, Journal of virology.

[317]  H. Tabuchi,et al.  Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor , 1990, Cell.

[318]  G. Wong,et al.  Molecular cloning and expression of a receptor for human tumor necrosis factor , 1990, Cell.

[319]  A. Barclay,et al.  Characterization of the MRC OX40 antigen of activated CD4 positive T lymphocytes‐‐a molecule related to nerve growth factor receptor. , 1990, The EMBO journal.

[320]  F. Emmrich,et al.  Expression of Activation Antigens on T Cells in Rheumatoid Arthritis Patients , 1990, Scandinavian journal of immunology.

[321]  M. Muhm,et al.  Further characterization of surface membrane structures expressed on human basophils and mast cells. , 1990, International archives of allergy and applied immunology.

[322]  S. Sprang,et al.  The structure of tumor necrosis factor-alpha at 2.6 A resolution. Implications for receptor binding. , 1990, The Journal of biological chemistry.

[323]  I. Maclennan,et al.  Mechanism of antigen-driven selection in germinal centres , 1989, Nature.

[324]  O. Majdic,et al.  Cultured human Langerhans cells resemble lymphoid dendritic cells in phenotype and function. , 1989, The Journal of investigative dermatology.

[325]  G. F. Burton,et al.  Antibody-forming cell induction during an early phase of germinal centre development and its delay with ageing. , 1989, Immunology.

[326]  R. Coffman,et al.  Brief Definitive Report TRANSFORMING GROWTH FACTOR # SPECIFICALLY ENHANCES IgA PRODUCTION BY LIPOPOLYSACCHARIDE-STIMULATED , 2022 .

[327]  J. Banchereau,et al.  Activation of human B lymphocytes through CD40 and interleukin 4 , 1989, European journal of immunology.

[328]  S. Fields,et al.  A novel genetic system to detect protein–protein interactions , 1989, Nature.

[329]  S. Nakamura,et al.  Anti-CD45 inhibition of human B cell proliferation depends on the nature of activation signals and the state of B cell activation. A study with anti-IgM and anti-CDw40 antibodies. , 1989, Journal of immunology.

[330]  D. Hart,et al.  Nodular sclerosing, mixed cellularity and lymphocyte-depleted variants of Hodgkin's disease are probable dendritic cell malignancies. , 1989, Clinical and experimental immunology.

[331]  G. Freeman,et al.  Isolated human follicular dendritic cells display a unique antigenic phenotype , 1989, The Journal of experimental medicine.

[332]  L. Young,et al.  Identification of a human epithelial cell surface protein sharing an epitope with the C3d/epstein‐barr virus receptor molecule of B lymphocytes , 1989, International journal of cancer.

[333]  I. Stamenkovic,et al.  A B‐lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas. , 1989, The EMBO journal.

[334]  D. I. Stuart,et al.  Structure of tumour necrosis factor , 1989, Nature.

[335]  S. Weissman,et al.  cDNA sequences of two inducible T-cell genes. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[336]  B. Ehlin‐Henriksson,et al.  The human B lymphocyte and carcinoma antigen, CDw40, is a phosphoprotein involved in growth signal transduction. , 1989, Journal of immunology.

[337]  H. Stein,et al.  Ki‐1 (CD30) antigen is released by Ki‐1‐positive tumor cells in vitro and in vivo. I. Partial characterization of soluble Ki‐1 antigen and detection of the antigen in cell culture supernatants and in serum by an enzyme‐linked immunosorbent assay , 1989, European journal of immunology.

[338]  B. Beutler,et al.  The biology of cachectin/TNF--a primary mediator of the host response. , 1989, Annual review of immunology.

[339]  W. Knapp Leucocyte typing IV : white cell differentiation antigens , 1989 .

[340]  E. Smeland,et al.  Triggering of neoplastic B cells via surface IgM and the cell surface antigens CD20 and CDw40. Responses differ from normal blood B cells and are restricted to certain morphologic subsets , 1988, International journal of cancer.

[341]  K. Arai,et al.  IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[342]  J. Banchereau,et al.  IgE production by normal human B cells induced by alloreactive T cell clones is mediated by IL-4 and suppressed by IFN-gamma. , 1988, Journal of immunology.

[343]  N. Ling,et al.  An analysis of myeloma plasma cell phenotype using antibodies defined at the IIIrd International Workshop on Human Leucocyte Differentiation Antigens. , 1988, Clinical and experimental immunology.

[344]  C. Perez,et al.  A novel form of TNF/cachectin is a cell surface cytotoxic transmembrane protein: Ramifications for the complex physiology of TNF , 1988, Cell.

[345]  G. Guy,et al.  Resting B lymphocytes can be triggered directly through the CDw40 (Bp50) antigen. A comparison with IL-4-mediated signaling. , 1988, Journal of immunology.

[346]  P. Distefano,et al.  Identification of a truncated form of the nerve growth factor receptor. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[347]  L. Wen,et al.  Theoretical and Practical Aspects of B‐Cell Activation: Murine and Human Systems , 1987, Immunological reviews.

[348]  E. Clark,et al.  Augmentation of normal and malignant B cell proliferation by monoclonal antibody to the B cell-specific antigen BP50 (CDW40). , 1987, Journal of immunology.

[349]  C. Jongeneel,et al.  Tumour necrosis factor and lymphotoxin genes map close to H–2D in the mouse major histocompatibility complex , 1987, Nature.

[350]  A. McMichael Leucocyte typing III : white cell differentiation antigens , 1987 .

[351]  G. Guy,et al.  Synergistic interaction between interleukin 4 and anti‐Bp50 (CDw40) revealed in a novel B cell restimulation assay , 1987, European journal of immunology.

[352]  M. Chao,et al.  Expression and structure of the human NGF receptor , 1986, Cell.

[353]  W. Fiers,et al.  Genes for the tumor necrosis factors alpha and beta are linked to the human major histocompatibility complex. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[354]  E. Clark,et al.  Activation of human B cells mediated through two distinct cell surface differentiation antigens, Bp35 and Bp50. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[355]  A. Ross,et al.  Gene transfer and molecular cloning of the human NGF receptor. , 1986, Science.

[356]  J. Hoxie,et al.  The nerve growth factor receptor gene is at human chromosome region 17q12-17q22, distal to the chromosome 17 breakpoint in acute leukemias. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[357]  T. Waldmann,et al.  Evidence for a defect in "switch" T cells in patients with immunodeficiency and hyperimmunoglobulinemia M. , 1986, The New England journal of medicine.

[358]  E. Unanue,et al.  Comment on the finding of Ia expression in nonlymphoid cells. , 1986, Laboratory investigation; a journal of technical methods and pathology.

[359]  L. Old,et al.  Tumor necrosis factor (TNF). , 1985, Science.

[360]  J. Strickler,et al.  Molecular cloning of the complementary DNA for human tumor necrosis factor. , 1985, Science.

[361]  Bharat B. Aggarwal,et al.  Human tumour necrosis factor: precursor structure, expression and homology to lymphotoxin , 1984, Nature.

[362]  B. Aggarwal,et al.  Cloning and expression of cDNA for human lymphotoxin, a lymphokine with tumour necrosis activity , 1984, Nature.

[363]  H. Ochs,et al.  Immunologic responses to bacteriophage phi-X 174 in immunodeficiency diseases. , 1971, The Journal of clinical investigation.