Sensitization of retinoids and corticoids to epigenetic drugs in MYC-activated lung cancers by antitumor reprogramming

[1]  Elisabeth Brambilla,et al.  PARD3 Inactivation in Lung Squamous Cell Carcinomas Impairs STAT3 and Promotes Malignant Invasion. , 2015, Cancer research.

[2]  A. Zelent,et al.  Unlocking the potential of retinoic acid in anticancer therapy , 2014, British Journal of Cancer.

[3]  M. Beksac,et al.  Panobinostat plus bortezomib and dexamethasone versus placebo plus bortezomib and dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma: a multicentre, randomised, double-blind phase 3 trial. , 2014, The Lancet. Oncology.

[4]  M. Sanchez-Cespedes,et al.  The SWI/SNF genetic blockade: effects in cell differentiation, cancer and developmental diseases , 2014, Oncogene.

[5]  J. Yokota,et al.  MAX inactivation in small cell lung cancer disrupts MYC-SWI/SNF programs and is synthetic lethal with BRG1. , 2014, Cancer discovery.

[6]  R. Greil,et al.  Lenalidomide in combination with vorinostat and dexamethasone for the treatment of relapsed/refractory peripheral T cell lymphoma (PTCL): report of a phase I/II trial , 2014, Annals of Hematology.

[7]  C. Rudin,et al.  Epigenetic therapy in non-small-cell lung cancer: targeting DNA methyltransferases and histone deacetylases , 2013, Expert opinion on biological therapy.

[8]  M. Fabbri,et al.  Epigenetic Therapy in Lung Cancer , 2013, Front. Oncol..

[9]  F. Setién,et al.  The tumour suppressor and chromatin-remodelling factor BRG1 antagonizes Myc activity and promotes cell differentiation in human cancer , 2012, EMBO molecular medicine.

[10]  J. Herman,et al.  Combination epigenetic therapy has efficacy in patients with refractory advanced non-small cell lung cancer. , 2011, Cancer discovery.

[11]  K. Gunderson,et al.  High density DNA methylation array with single CpG site resolution. , 2011, Genomics.

[12]  R. Young,et al.  BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc , 2011, Cell.

[13]  C. Roberts,et al.  SWI/SNF nucleosome remodellers and cancer , 2011, Nature Reviews Cancer.

[14]  M. Esteller,et al.  Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome , 2011, Epigenetics.

[15]  D. Pisano,et al.  Massive parallel DNA pyrosequencing analysis of the tumor suppressor BRG1/SMARCA4 in lung primary tumors , 2011, Human mutation.

[16]  W. Cardoso,et al.  Mechanisms of lung development: contribution to adult lung disease and relevance to chronic obstructive pulmonary disease. , 2009, Proceedings of the American Thoracic Society.

[17]  E. Galanis,et al.  Vorinostat in solid and hematologic malignancies , 2009, Journal of hematology & oncology.

[18]  M. Relling,et al.  The SWI/SNF chromatin-remodeling complex and glucocorticoid resistance in acute lymphoblastic leukemia. , 2008, Journal of the National Cancer Institute.

[19]  Cem Elbi,et al.  Chromatin remodeling complexes interact dynamically with a glucocorticoid receptor-regulated promoter. , 2008, Molecular biology of the cell.

[20]  Todd R Golub,et al.  Expression-based screening identifies the combination of histone deacetylase inhibitors and retinoids for neuroblastoma differentiation , 2008, Proceedings of the National Academy of Sciences.

[21]  Jun Yokota,et al.  Frequent BRG1/SMARCA4–inactivating mutations in human lung cancer cell lines , 2008, Human mutation.

[22]  J. Cigudosa,et al.  Expression signatures in lung cancer reveal a profile for EGFR‐mutant tumours and identify selective PIK3CA overexpression by gene amplification , 2008, The Journal of pathology.

[23]  Sreenath V. Sharma,et al.  Oncogene addiction: setting the stage for molecularly targeted cancer therapy. , 2007, Genes & development.

[24]  A. Iafrate,et al.  Identification of genotype-correlated sensitivity to selective kinase inhibitors by using high-throughput tumor cell line profiling , 2007, Proceedings of the National Academy of Sciences.

[25]  B. Lefebvre,et al.  The core component of the mammalian SWI/SNF complex SMARCD3/BAF60c is a coactivator for the nuclear retinoic acid receptor , 2007, Molecular and Cellular Endocrinology.

[26]  E. Moran,et al.  The c-myc gene is a direct target of mammalian SWI/SNF-related complexes during differentiation-associated cell cycle arrest. , 2006, Cancer research.

[27]  K. Kroll,et al.  The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD , 2004, Development.

[28]  Charles A Powell,et al.  Non-small-cell lung cancer molecular signatures recapitulate lung developmental pathways. , 2003, The American journal of pathology.

[29]  Sharmistha Pal,et al.  mSin3A/Histone Deacetylase 2- and PRMT5-Containing Brg1 Complex Is Involved in Transcriptional Repression of the Myc Target Gene cad , 2003, Molecular and Cellular Biology.

[30]  Daniel Metzger,et al.  Sequential roles of Brg, the ATPase subunit of BAF chromatin remodeling complexes, in thymocyte development. , 2003, Immunity.

[31]  H. Rutz.  Effects of corticosteroid use on treatment of solid tumours , 2002, The Lancet.

[32]  S. Collins.  The role of retinoids and retinoic acid receptors in normal hematopoiesis , 2002, Leukemia.

[33]  W. Rom,et al.  Glucocorticoids inhibit lung cancer cell growth through both the extracellular signal-related kinase pathway and cell cycle regulators. , 2002, American journal of respiratory cell and molecular biology.

[34]  A. Imbalzano,et al.  Mammalian SWI/SNF complexes promote MyoD-mediated muscle differentiation , 2001, Nature Genetics.

[35]  C. Mendelsohn,et al.  Regulation of retinoic acid signaling during lung morphogenesis. , 2000, Development.

[36]  S. G. Cheng,et al.  c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation function , 1999, Nature Genetics.

[37]  T. Archer,et al.  Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex , 1998, Nature.

[38]  G. Brodeur,et al.  Autoregulation of the human N-myc oncogene is disrupted in amplified but not single-copy neuroblastoma cell lines , 1997, Oncogene.

[39]  O. Wrange,et al.  Glucocorticoid receptor-glucocorticoid response element binding stimulates nucleosome disruption by the SWI/SNF complex , 1997, Molecular and cellular biology.

[40]  L. M. Facchini,et al.  The Myc negative autoregulation mechanism requires Myc-Max association and involves the c-myc P2 minimal promoter , 1997, Molecular and cellular biology.

[41]  Michael R. Green,et al.  Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex , 1994, Nature.

[42]  H. Chiba,et al.  Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor. , 1994, Nucleic acids research.

[43]  M. Scott,et al.  Five SWI/SNF gene products are components of a large multisubunit complex required for transcriptional enhancement. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[44]  C. Wilson,et al.  Identification of Hox genes in newborn lung and effects of gestational age and retinoic acid on their expression. , 1994, The American journal of physiology.

[45]  A. Malik,et al.  Thrombin receptor activation peptide induces pulmonary vasoconstriction. , 1994, The American journal of physiology.

[46]  J. Minna,et al.  Human lung cancer cell lines exhibit resistance to retinoic acid treatment. , 1993, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[47]  E. Thompson,et al.  Suppression of c-myc is a critical step in glucocorticoid-induced human leukemic cell lysis. , 1993, The Journal of biological chemistry.

[48]  R. Lovell-Badge,et al.  Novel transcriptional targets of the SRY-HMG box transcription factor SOX4 link its expression to the development of small cell lung cancer. , 2012, Cancer research.

[49]  Ronit Vogt Sionov,et al.  Mechanisms regulating the susceptibility of hematopoietic malignancies to glucocorticoid-induced apoptosis. , 2008, Advances in cancer research.

[50]  Jeffrey A Whitsett,et al.  Transcriptional control of lung morphogenesis. , 2007, Physiological reviews.

[51]  R. Montesano,et al.  Experimental cancer of the lung. Inhibition by vitamin A of the induction of tracheobronchial squamous metaplasia and squamous cell tumors , 1967, Cancer.