Direct 3D Printing of Shear‐Thinning Hydrogels into Self‐Healing Hydrogels

Supramolecular hydrogels are used in the 3D printing of high-resolution, multi-material structures. The non-covalent bonds allow the extrusion of the inks into support gels to directly write structures continuously in 3D space. This material system supports the patterning of multiple inks, cells, and void spaces.

[1]  Emanuel M. Sachs,et al.  Solid free-form fabrication of drug delivery devices , 1996 .

[2]  R. Mülhaupt,et al.  Emulsifier‐Free Graphene Dispersions with High Graphene Content for Printed Electronics and Freestanding Graphene Films , 2012 .

[3]  J. Lewis,et al.  3D Bioprinting of Vascularized, Heterogeneous Cell‐Laden Tissue Constructs , 2014, Advanced materials.

[4]  J. Muth,et al.  3D Printing of Free Standing Liquid Metal Microstructures , 2013, Advanced materials.

[5]  Brendon M. Baker,et al.  Rapid casting of patterned vascular networks for perfusable engineered 3D tissues , 2012, Nature materials.

[6]  Brian Derby,et al.  Printing and Prototyping of Tissues and Scaffolds , 2012, Science.

[7]  Jason A Burdick,et al.  Shear‐Thinning Supramolecular Hydrogels with Secondary Autonomous Covalent Crosslinking to Modulate Viscoelastic Properties In Vivo , 2015, Advanced functional materials.

[8]  D. D’Lima,et al.  Direct human cartilage repair using three-dimensional bioprinting technology. , 2012, Tissue engineering. Part A.

[9]  Joe Tien,et al.  Fabrication of microfluidic hydrogels using molded gelatin as a sacrificial element. , 2007, Lab on a chip.

[10]  Kytai Truong Nguyen,et al.  Photopolymerizable hydrogels for tissue engineering applications. , 2002, Biomaterials.

[11]  Kirk Czymmek,et al.  Injectable solid peptide hydrogel as a cell carrier: effects of shear flow on hydrogels and cell payload. , 2012, Langmuir : the ACS journal of surfaces and colloids.

[12]  D. Fingar,et al.  The mTOR/p70 S6K1 pathway regulates vascular smooth muscle cell differentiation. , 2004, American journal of physiology. Cell physiology.

[13]  F. Lin,et al.  Generation of three-dimensional hepatocyte/gelatin structures with rapid prototyping system. , 2006, Tissue engineering.

[14]  Alexandra L. Rutz,et al.  A Multimaterial Bioink Method for 3D Printing Tunable, Cell‐Compatible Hydrogels , 2015, Advanced materials.

[15]  K H Kang,et al.  Rapid 3D printing of anatomically accurate and mechanically heterogeneous aortic valve hydrogel scaffolds , 2012, Biofabrication.

[16]  Vladimir Mironov,et al.  Organ printing: computer-aided jet-based 3D tissue engineering. , 2003, Trends in biotechnology.

[17]  Jason P. Gleghorn,et al.  Microfluidic scaffolds for tissue engineering. , 2007, Nature materials.

[18]  O. Scherman,et al.  Supramolecular polymeric hydrogels. , 2012, Chemical Society reviews.

[19]  J. Burdick,et al.  Secondary Photocrosslinking of Injectable Shear‐Thinning Dock‐and‐Lock Hydrogels , 2013, Advanced healthcare materials.

[20]  Sebastian Seiffert,et al.  Physical chemistry of supramolecular polymer networks. , 2012, Chemical Society reviews.

[21]  Jason A Burdick,et al.  Review: photopolymerizable and degradable biomaterials for tissue engineering applications. , 2007, Tissue engineering.

[22]  James J. Yoo,et al.  Complex heterogeneous tissue constructs containing multiple cell types prepared by inkjet printing technology. , 2013, Biomaterials.

[23]  Jason A Burdick,et al.  Hydrolytically degradable hyaluronic acid hydrogels with controlled temporal structures. , 2008, Biomacromolecules.

[24]  Michael C. McAlpine,et al.  3D printed quantum dot light-emitting diodes. , 2014, Nano letters.

[25]  Wim E Hennink,et al.  25th Anniversary Article: Engineering Hydrogels for Biofabrication , 2013, Advanced materials.

[26]  Sarit B. Bhaduri,et al.  Drop-on-demand printing of cells and materials for designer tissue constructs , 2007 .

[27]  Shannon E Bakarich,et al.  Extrusion printing of ionic-covalent entanglement hydrogels with high toughness. , 2013, Journal of materials chemistry. B.

[28]  Jason A. Burdick,et al.  Hyaluronic Acid Hydrogels for Biomedical Applications , 2011, Advanced materials.

[29]  Brian A. Aguado,et al.  Improving viability of stem cells during syringe needle flow through the design of hydrogel cell carriers. , 2012, Tissue engineering. Part A.

[30]  G. Prestwich,et al.  Photocrosslinkable hyaluronan-gelatin hydrogels for two-step bioprinting. , 2010, Tissue engineering. Part A.

[31]  Thomas Braschler,et al.  Microdrop Printing of Hydrogel Bioinks into 3D Tissue‐Like Geometries , 2012, Advanced materials.

[32]  Murat Guvendiren,et al.  Shear-thinning hydrogels for biomedical applications , 2012 .

[33]  Jason A Burdick,et al.  Rational design of network properties in guest-host assembled and shear-thinning hyaluronic acid hydrogels. , 2013, Biomacromolecules.

[34]  K. Anseth,et al.  Hydrogel Cell Cultures , 2007, Science.

[35]  Anthony Atala,et al.  3D bioprinting of tissues and organs , 2014, Nature Biotechnology.

[36]  M. Grinstaff,et al.  Photocrosslinkable polysaccharides for in situ hydrogel formation. , 2001, Journal of biomedical materials research.

[37]  J. Malda,et al.  Biofabrication of multi-material anatomically shaped tissue constructs , 2013, Biofabrication.

[38]  Dongsheng Liu,et al.  Rapid formation of a supramolecular polypeptide-DNA hydrogel for in situ three-dimensional multilayer bioprinting. , 2015, Angewandte Chemie.

[39]  Deok‐Ho Kim,et al.  Printing three-dimensional tissue analogues with decellularized extracellular matrix bioink , 2014, Nature Communications.

[40]  Murat Guvendiren,et al.  Engineering synthetic hydrogel microenvironments to instruct stem cells. , 2013, Current opinion in biotechnology.

[41]  J. Lewis,et al.  3D‐Printing of Lightweight Cellular Composites , 2014, Advanced materials.