The physionet QT database: Study on the reliability of P-wave manual annotations under noisy recordings

Thanks to its manual annotations, the PhysioNet QT database (QTDB) has been widely used as the reference of ECG delineators. However, a significant percentage of its annotations have been reported as inaccurate. Thus, any precise ECG delineator will never be able to meet, without error, all its annotations. The present work analyzes these inaccuracies and also how noise altered the final timing of annotations. As this effect is higher for low amplitude waveforms, P-waves were studied through a robust P-wave delineator. Its delineation results were compared with manual annotations under two scenarios. Firstly, a direct comparison without ECG denoising was performed. Secondly, the P-waves were delineated after efficient Wavelet-based denoising. Results showed that automatic annotations were closer to manual annotations for noisy ECGs and farther in the case of denoised ECGs, thus proving that noise altered the timing of manual annotations. An unreal improvement in delineation performance for noisy ECGs was obtained for P-wave onset, peak and offset in 45.83%, 57.29% and 56.25% of the recordings, respectively. Thus, to improve delineators reliability, either the need to review the QTDB annotations or its replacement by a better annotated database are suggested.

[1]  Raúl Alcaraz,et al.  Electrocardiographic P-wave delineation based on adaptive slope Gaussian detection , 2017, 2017 Computing in Cardiology (CinC).

[2]  Iñaki Romero,et al.  Comparative study of algorithms for ECG segmentation , 2017, Biomed. Signal Process. Control..

[3]  G.B. Moody,et al.  The impact of the MIT-BIH Arrhythmia Database , 2001, IEEE Engineering in Medicine and Biology Magazine.

[4]  Jared W. Magnani,et al.  P Wave Indices: Current Status and Future Directions in Epidemiology, Clinical, and Research Applications , 2009, Circulation. Arrhythmia and electrophysiology.

[5]  G. Moody,et al.  The European ST-T database: standard for evaluating systems for the analysis of ST-T changes in ambulatory electrocardiography. , 1992, European heart journal.

[6]  Raúl Alcaraz,et al.  Application of the phasor transform for automatic delineation of single-lead ECG fiducial points , 2010, Physiological measurement.

[7]  Pablo Laguna,et al.  A database for evaluation of algorithms for measurement of QT and other waveform intervals in the ECG , 1997, Computers in Cardiology 1997.

[8]  Prabin Kumar Bora,et al.  Electrocardiogram signal denoising using non-local wavelet transform domain filtering , 2015, IET Signal Process..

[9]  Olaf Dössel,et al.  P wave detection and delineation in the ECG based on the phase free stationary wavelet transform and using intracardiac atrial electrograms as reference , 2016, Biomedizinische Technik. Biomedical engineering.

[10]  Xia Liu,et al.  Ccdd: an Enhanced Standard ECG Database with its Management and Annotation Tools , 2012, Int. J. Artif. Intell. Tools.

[11]  J H van Bemmel,et al.  A reference data base for multilead electrocardiographic computer measurement programs. , 1987, Journal of the American College of Cardiology.

[12]  Raúl Alcaraz,et al.  The Genesis of the Electrocardiogram (ECG) , 2017 .