Apraxia and the supplementary motor area.

Anatomical, electrophysiological, and cerebral blood flow studies suggest that the supplementary motor area (SMA) may be important for programming certain skilled motor acts of the limbs. However, to our knowledge, abnormalities of complex distal motor behavior following SMA lesions have not been reported. We have studied two patients with left mesial hemisphere infarctions that included the SMA. These patients had bilateral ideomotor apraxia for transitive limb movements without buccofacial apraxia. The observations suggest that the types of skilled motor acts programmed by the left SMA are learned transitive limb movements.

[1]  C. Brinkman Supplementary motor area of the monkey's cerebral cortex: short- and long-term deficits after unilateral ablation and the effects of subsequent callosal section , 1984, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[2]  J. Talairach,et al.  Clinical consequences of corticectomies involving the supplementary motor area in man , 1977, Journal of the Neurological Sciences.

[3]  J. Tanji,et al.  Supplementary motor area: neuronal response to motor instructions. , 1980, Journal of neurophysiology.

[4]  H. Funkenstein,et al.  Broca aphasia , 1978, Neurology.

[5]  P. Strick,et al.  Frontal lobe inputs to primate motor cortex: evidence for four somatotopically organized ‘premotor’ areas , 1979, Brain Research.

[6]  K. Heilman,et al.  Two forms of ideomotor apraxia , 1982, Neurology.

[7]  A. Rubens Aphasia With Infarction in the Territory of the Anterior Cerebral Artery , 1975, Cortex.

[8]  M. Wiesendanger,et al.  Why Transcortical Reflexes? , 1975, Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques.

[9]  P. Strick,et al.  The origin of thalamic inputs to the arcuate premotor and supplementary motor areas , 1984, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[10]  C. Woolsey,et al.  Patterns of localization in precentral and "supplementary" motor areas and their relation to the concept of a premotor area. , 1952, Research publications - Association for Research in Nervous and Mental Disease.

[11]  D. Denny-Brown THE NATURE OF APRAXIA , 1958, The Journal of nervous and mental disease.

[12]  H. Spinnler,et al.  Is ideomotor apraxia the outcome of damage to well-defined regions of the left hemisphere? Neuropsychological study of CAT correlation. , 1980, Journal of neurology, neurosurgery, and psychiatry.

[13]  N. Geschwind,et al.  A Human Cerebral Deconnection Syndrome , 1974 .

[14]  T. Powell,et al.  Connexions of the somatic sensory cortex of the rhesus monkey. II. Contralateral cortical connexions. , 1969, Brain : a journal of neurology.

[15]  W. Sweet SEEPING INTRACRANIAL ANEURYSM SIMULATING NEOPLASM: SYNDROME OF THE CORPUS CALLOSUM , 1941 .

[16]  C. Brinkman,et al.  Supplementary motor area in the monkey: activity of neurons during performance of a learned motor task. , 1979, Journal of neurophysiology.

[17]  M. Alexander,et al.  The aphasia syndrome of stroke in the left anterior cerebral artery territory. , 1980, Archives of neurology.

[18]  D. G. Lawrence,et al.  The functional organization of the motor system in the monkey. I. The effects of bilateral pyramidal lesions. , 1968, Brain : a journal of neurology.

[19]  H. Kuypers,et al.  Intrahemispheric cortical connexions and visual guidance of hand and finger movements in the rhusus monkey. , 1975, Brain : a journal of neurology.

[20]  E. Kaplan,et al.  The Boston naming test , 2001 .

[21]  E. G. Jones,et al.  Intracortical connectivity of architectonic fields in the somatic sensory, motor and parietal cortex of monkeys , 1978, The Journal of comparative neurology.

[22]  H. Künzle An autoradiographic analysis of the efferent connections from premotor and adjacent prefrontal regions (areas 6 and 9) in macaca fascicularis. , 1978, Brain, behavior and evolution.

[23]  R. L. Greene,et al.  Changes in neuropsychological functioning in an aging population. , 1980, Journal of consulting and clinical psychology.

[24]  W PENFIELD,et al.  The supplementary motor area of the cerebral cortex; a clinical and experimental study. , 1951, A.M.A. archives of neurology and psychiatry.

[25]  S Jonas,et al.  The supplementary motor region and speech emission. , 1981, Journal of communication disorders.

[26]  H. Funkenstein,et al.  Aphasia following infarction of the left supplementary motor area , 1978, Neurology.

[27]  K. Haaland,et al.  The different types of limb apraxia errors made by patients with left vs. right hemisphere damage , 1984, Brain and Cognition.

[28]  U. Jürgens,et al.  The efferent and afferent connections of the supplementary motor area , 1984, Brain Research.

[29]  A M Galaburda,et al.  Aphemia. Clinical-anatomic correlations. , 1983, Archives of neurology.

[30]  Arthur L. Benton,et al.  Word fluency and brain damage , 1967 .

[31]  O. Foerster,et al.  THE MOTOR CORTEX IN MAN IN THE LIGHT OF HUGHLINGS JACKSON'S DOCTRINES , 1936 .

[32]  Allan M. Smith The activity of supplementary motor area neurons during a maintained precision grip , 1979, Brain Research.

[33]  J. Tanji,et al.  Supplementary and precentral motor cortex: Contrast in responsiveness to peripheral input in the hindlimb area of the unanesthetized monkey , 1981, The Journal of comparative neurology.

[34]  B. Larsen,et al.  Activation of the supplementary motor area during voluntary movement in man suggests it works as a supramotor area. , 1979, Science.

[35]  H. Kuypers,et al.  Precentral projections to different parts of the spinal intermediate zone in therhesus monkey. , 1970, Brain research.

[36]  D. L. Ratusnik,et al.  Northwestern Syntax Screening Test: a short form. , 1980, The Journal of speech and hearing disorders.

[37]  P. Roland,et al.  Supplementary motor area and other cortical areas in organization of voluntary movements in man. , 1980, Journal of neurophysiology.

[38]  L. Vignolo,et al.  Brain lesions associated with oral apraxia in stroke patients: A clinico-neuroradiological investigation with the CT scan , 1980, Neuropsychologia.

[39]  A. Basso,et al.  Historical Perspectives On Neuroanatomical Correlates of Limb Apraxia , 1985 .

[40]  E. Murray,et al.  Organization of corticospinal neurons in the monkey , 1981, The Journal of comparative neurology.

[41]  N. Geschwind The apraxias: neural mechanisms of disorders of learned movement. , 1975, American scientist.

[42]  C. Woolsey Cortical Motor Map of Macaca Mulatta after Chronic Section of the Medullary Pyramid , 1975 .