Abnormally expanded pro‐B hematogones associated with congenital cytomegalovirus infection

Hematogones are nonleukemic immature lymphocytes that display a B‐precursor phenotype and populate the pediatric bone marrow. We present the case of a newborn with an atypical, marked expansion of hematogones similar to the pro‐B cells of infant acute lymphoblastic leukemia, which demonstrated their nonleukemic nature through gene rearrangement analysis and were associated with a congenital cytomegalovirus infection. Am. J. Hematol. 82:934–936, 2007. © 2007 Wiley‐Liss, Inc.

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