Pneumococcal sepsis with generalised Shwartzman reaction.

. A patient in hospital developed acute pneumococcal sepsis during which lesions typical of the generalised Shwartzman reaction appeared. The patient went into shock, showed signs of respiratory distress, she had haemorrhagic necrosis of the skin and transient anuria but ultimately recovered. Detailed investigation of the haemostatic and fibrinolytic systems revealed rapid consumption of platelets, decreased prothrombin and factor V, and a large increase of fibrinolytic split products.

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