Regulation of transcription by proteins that control the cell cycle

In eukaryotes, progression of a cell through the cell cycle is partly controlled at the level of transcriptional regulation. Yeast and mammalian cells use similar mechanisms to achieve this regulation. Although gaps still remain, progress has been made recently in connecting the links between the cell's cycle and its transcriptional machinery.

[1]  Y. Qian,et al.  The retinoblastoma gene product regulates progression through the G1 phase of the cell cycle , 1991, Cell.

[2]  R. Young,et al.  A kinase–cyclin pair in the RNA polymerase II holoenzyme , 1995, Nature.

[3]  R. Weinberg,et al.  The retinoblastoma protein and cell cycle control , 1995, Cell.

[4]  R. Weinberg,et al.  A cyclin associated with the CDK-activating kinase MO15 , 1994, Nature.

[5]  T. Jacks,et al.  Tumor Induction and Tissue Atrophy in Mice Lacking E2F-1 , 1996, Cell.

[6]  K. Nasmyth,et al.  Cell cycle regulated transcription in yeast. , 1994, Current opinion in cell biology.

[7]  B. Dynlacht,et al.  Transcriptional control of the cell cycle. , 1996, Current opinion in cell biology.

[8]  D. Livingston,et al.  Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members. , 1995, Genes & development.

[9]  B. Dynlacht,et al.  Differential regulation of E2F transactivation by cyclin/cdk2 complexes. , 1994, Genes & development.

[10]  N. Heintz,et al.  Mitotic regulation of TFIID: inhibition of activator-dependent transcription and changes in subcellular localization. , 1996, Genes & development.

[11]  Wanjin Hong,et al.  A role for retinoblastoma protein in potentiating transcriptional activation by the glucocorticoid receptor , 1995, Nature.

[12]  G. Faye,et al.  Civ1 (CAK In Vivo), a Novel Cdk-Activating Kinase , 1996, Cell.

[13]  R. Weinberg,et al.  Regulation of retinoblastoma protein functions by ectopic expression of human cyclins , 1992, Cell.

[14]  D. Forbes,et al.  Mitotic repression of RNA polymerase III transcription in vitro mediated by phosphorylation of a TFIIIB component. , 1994, Science.

[15]  A. Gronenborn,et al.  The P53 Tumor Suppressor Protein , 1995 .

[16]  R. Conaway,et al.  Multifunctional RNA polymerase II initiation factor delta from rat liver. Relationship between carboxyl-terminal domain kinase, ATPase, and DNA helicase activities. , 1993, The Journal of biological chemistry.

[17]  P. Kaldis,et al.  The Cdk-Activating Kinase (CAK) from Budding Yeast , 1996, Cell.

[18]  H. Erdjument-Bromage,et al.  A Cyclin-Dependent Kinase-Activating Kinase (CAK) in Budding Yeast Unrelated to Vertebrate CAK , 1996, Science.

[19]  M. Ewen,et al.  Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein. , 1993, Genes & development.

[20]  R. Weinberg,et al.  Shared role of the pRB-related p130 and p107 proteins in limb development. , 1996, Genes & development.

[21]  G. Peters,et al.  Cdk2‐dependent phosphorylation of Id2 modulates activity of E2A‐related transcription factors , 1997, The EMBO journal.

[22]  K. Ozato,et al.  Displacement of sequence-specific transcription factors from mitotic chromatin , 1995, Cell.

[23]  E. Nigg Cyclin-dependent kinase 7: at the cross-roads of transcription, DNA repair and cell cycle control? , 1996, Current opinion in cell biology.

[24]  R. Weinberg,et al.  Requirement for TFIIH kinase activity in transcription by RNA polymerase II , 1995, Nature.

[25]  D. Reinberg,et al.  Human general transcription factor IIH phosphorylates the C-terminal domain of RNA polymerase II , 1992, Nature.

[26]  N. L. La Thangue,et al.  Transcriptional repression by the Rb-related protein p107. , 1993, Molecular biology of the cell.

[27]  J. Harper,et al.  Cyclin D1/Cdk4 regulates retinoblastoma protein-mediated cell cycle arrest by site-specific phosphorylation. , 1997, Molecular biology of the cell.

[28]  P. Friedman,et al.  Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[29]  M. Carlson,et al.  Cyclin-dependent protein kinase and cyclin homologs SSN3 and SSN8 contribute to transcriptional control in yeast. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[30]  A. Sancar Mechanisms of DNA excision repair. , 1994, Science.

[31]  B. Dynlacht,et al.  p130 and p107 use a conserved domain to inhibit cellular cyclin-dependent kinase activity , 1997, Molecular and cellular biology.

[32]  Uttam Surana,et al.  The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SW15 , 1991, Cell.

[33]  B. Dynlacht,et al.  p107 uses a p21CIP1-related domain to bind cyclin/cdk2 and regulate interactions with E2F. , 1995, Genes & development.

[34]  M. Greenberg,et al.  E2F-1 Functions in Mice to Promote Apoptosis and Suppress Proliferation , 1996, Cell.

[35]  P. L. Chen,et al.  Suppression of the neoplastic phenotype by replacement of the RB gene in human cancer cells. , 1988, Science.

[36]  S. Jackson,et al.  Repression of RNA polymerase III transcription by the retinoblastoma protein , 1996, Nature.

[37]  F. C. Lucibello,et al.  Cell Cycle Regulation of E2F Site Occupation in Vivo , 1996, Science.

[38]  K Nasmyth,et al.  Switching transcription on and off during the yeast cell cycle: Cln/Cdc28 kinases activate bound transcription factor SBF (Swi4/Swi6) at start, whereas Clb/Cdc28 kinases displace it from the promoter in G2. , 1996, Genes & development.

[39]  Mike Tyers,et al.  Mechanisms that help the yeast cell cycle clock tick: G2 cyclins transcriptionally activate G2 cyclins and repress G1 cyclins , 1993, Cell.

[40]  J. Egly,et al.  Substrate specificity of the cdk‐activating kinase (CAK) is altered upon association with TFIIH , 1997, The EMBO journal.

[41]  J. Hoeijmakers,et al.  The MO15 cell cycle kinase is associated with the TFIIH transcription-DNA repair factor , 1994, Cell.

[42]  R. Kornberg,et al.  CTD kinase associated with yeast RNA polymerase II initiation factor b , 1991, Cell.

[43]  J. Nevins,et al.  Autoregulatory control of E2F1 expression in response to positive and negative regulators of cell cycle progression. , 1994, Genes & development.

[44]  T. Maimets,et al.  p53 interacts with p34cdc2 in mammalian cells: implications for cell cycle control and oncogenesis. , 1990, Oncogene.

[45]  D. Reinberg,et al.  Cdk-activating kinase complex is a component of human transcription factor TFIIH , 1995, Nature.

[46]  T. Jacks,et al.  Targeted disruption of p107: functional overlap between p107 and Rb. , 1996, Genes & development.

[47]  E. Nigg,et al.  Identification of human cyclin-dependent kinase 8, a putative protein kinase partner for cyclin C. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[48]  J. Nevins,et al.  The interaction of RB with E2F coincides with an inhibition of the transcriptional activity of E2F. , 1992, Genes & development.

[49]  D. Reinberg,et al.  A human RNA polymerase II complex associated with SRB and DNA-repair proteins , 1996, Nature.

[50]  E. Lees,et al.  Cyclin C/CDK8 is a novel CTD kinase associated with RNA polymerase II. , 1996, Oncogene.

[51]  R. Young,et al.  Association of Cdk-activating kinase subunits with transcription factor TFIIH , 1995, Nature.

[52]  N. Dyson pRB, p107 and the regulation of the E2F transcription factor , 1994, Journal of Cell Science.

[53]  Wilhelm Krek,et al.  Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase , 1994, Cell.

[54]  L. Taylor,et al.  Activity of RNA polymerase I transcription factor UBF blocked by Rb gene product , 1995, Nature.

[55]  J. Manfredi,et al.  The p53 tumor suppressor protein: meeting review. , 1993, Genes & development.

[56]  C. Prives,et al.  Cell-cycle related regulation of poly(A) polymerase by phosphorylation , 1996, Nature.

[57]  C. Prives,et al.  Increased and altered DNA binding of human p53 by S and G2/M but not Gl cyclin-dependent kinases , 1995, Nature.

[58]  S. Weintraub,et al.  Mechanism of active transcriptional repression by the retinoblastoma protein , 1995, Nature.

[59]  R. Conaway,et al.  An RNA polymerase II transcription factor has an associated DNA-dependent ATPase (dATPase) activity strongly stimulated by the TATA region of promoters. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[60]  B. Dynlacht,et al.  Specific regulation of E2F family members by cyclin-dependent kinases , 1997, Molecular and cellular biology.

[61]  J. Nevins,et al.  Cell cycle regulation of the E2F transcription factor involves an interaction with cyclin A , 1991, Cell.

[62]  R. Watson,et al.  B-Myb function can be markedly enhanced by cyclin A-dependent kinase and protein truncation , 1997, Oncogene.

[63]  D. Bentley,et al.  Regulation of CDK7 substrate specificity by MAT1 and TFIIH , 1997, The EMBO journal.

[64]  R. Kornberg,et al.  Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK , 1994, Cell.

[65]  Danny Reinberg,et al.  A human RNA polymerase II complex associated with SRB and DNA-repair proteins , 1996, Nature.

[66]  S. Reed,et al.  Isolation of three novel human cyclins by rescue of G1 cyclin (cln) function in yeast , 1991, Cell.

[67]  S. Reed,et al.  KIN28 encodes a C-terminal domain kinase that controls mRNA transcription in Saccharomyces cerevisiae but lacks cyclin-dependent kinase-activating kinase (CAK) activity , 1995, Molecular and cellular biology.

[68]  P. Sharp,et al.  A kinase-deficient transcription factor TFIIH is functional in basal and activated transcription. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[69]  David O. Morgan,et al.  A novel cyclin associates with M015/CDK7 to form the CDK-activating kinase , 1994, Cell.

[70]  S. Weintraub,et al.  Retinoblastoma protein switches the E2F site from positive to negative element , 1992, Nature.

[71]  P. O’Farrell,et al.  An evolutionarily conserved cyclin homolog from Drosophila rescues yeast deficient in G1 cyclins , 1991, Cell.