DistributedFBA.jl: high‐level, high‐performance flux balance analysis in Julia

Motivation: Flux balance analysis and its variants are widely used methods for predicting steady‐state reaction rates in biochemical reaction networks. The exploration of high dimensional networks with such methods is currently hampered by software performance limitations. Results: DistributedFBA.jl is a high‐level, high‐performance, open‐source implementation of flux balance analysis in Julia. It is tailored to solve multiple flux balance analyses on a subset or all the reactions of large and huge‐scale networks, on any number of threads or nodes. Availability and Implementation: The code is freely available on github.com/opencobra/COBRA.jl. The documentation can be found at opencobra.github.io/COBRA.jl. Contact: ronan.mt.fleming@gmail.com Supplementary information: Supplementary data are available at Bioinformatics online.

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