Analysis and prediction of mitochondrial targeting signals.
暂无分享,去创建一个
[1] G. von Heijne,et al. Domain structure of mitochondrial and chloroplast targeting peptides. , 1989, European journal of biochemistry.
[2] D. Hoyt,et al. Conformational analysis of a mitochondrial presequence derived from the F1-ATPase beta-subunit by CD and NMR spectroscopy. , 1992, Biochimica et biophysica acta.
[3] W. Neupert,et al. Signal-Anchor Domains of Proteins of the Outer Membrane of Mitochondria , 2003, Journal of Biological Chemistry.
[4] R. Jensen,et al. MAS6 encodes an essential inner membrane component of the yeast mitochondrial protein import pathway , 1993, The Journal of cell biology.
[5] W. Fenton,et al. Cleavage of precursors by the mitochondrial processing peptidase requires a compatible mature protein or an intermediate octapeptide , 1991, The Journal of cell biology.
[6] R. Scarpulla,et al. Mitochondrial targeting of yeast apoiso-1-cytochrome c is mediated through functionally independent structural domains , 1990, Molecular and cellular biology.
[7] W. Neupert,et al. Protein Import Into Mitochondria , 2001, IUBMB life.
[8] S. Brunak,et al. Predicting subcellular localization of proteins based on their N-terminal amino acid sequence. , 2000, Journal of molecular biology.
[9] W. Neupert,et al. Mitochondrial protein import: Nucleoside triphosphates are involved in conferring import-competence to precursors , 1987, Cell.
[10] N. Pfanner,et al. Insertion of hydrophobic membrane proteins into the inner mitochondrial membrane--a guided tour. , 2003, Journal of molecular biology.
[11] B. Tursun,et al. A novel two-step mechanism for removal of a mitochondrial signal sequence involves the mAAA complex and the putative rhomboid protease Pcp1. , 2002, Journal of molecular biology.
[12] W. Neupert,et al. Uniform nomenclature for the mitochondrial peptidases cleaving precursors of mitochondrial proteins , 1993 .
[13] K. Nakai,et al. PSORT: a program for detecting sorting signals in proteins and predicting their subcellular localization. , 1999, Trends in biochemical sciences.
[14] Walter Neupert,et al. Evolutionary conservation of biogenesis of β-barrel membrane proteins , 2003, Nature.
[15] D. Gorenstein,et al. Amphiphilicity determines binding properties of three mitochondrial presequences to lipid surfaces. , 1996, Biochemistry.
[16] R. Durbin,et al. Pfam: A comprehensive database of protein domain families based on seed alignments , 1997, Proteins.
[17] N. Pfanner,et al. Versatility of the mitochondrial protein import machinery , 2001, Nature Reviews Molecular Cell Biology.
[18] M. Freeman,et al. Mitochondrial membrane remodelling regulated by a conserved rhomboid protease , 2003, Nature.
[19] W. Neupert,et al. Mitochondria‐targeted green fluorescent proteins: convenient tools for the study of organelle biogenesis in Saccharomyces cerevisiae , 2000, Yeast.
[20] B. de Kruijff,et al. A novel property of a mitochondrial presequence , 1993, FEBS letters.
[21] D. Vaux,et al. Mature DIABLO/Smac is produced by the IMP protease complex on the mitochondrial inner membrane. , 2005, Molecular biology of the cell.
[22] F. Sherman,et al. Coupling of heme attachment to import of cytochrome c into yeast mitochondria. Studies with heme lyase-deficient mitochondria and altered apocytochromes c. , 1988, The Journal of biological chemistry.
[23] K. Mihara,et al. Targeting and Assembly of Mitochondrial Tail-anchored Protein Tom5 to the TOM Complex Depend on a Signal Distinct from That of Tail-anchored Proteins Dispersed in the Membrane* , 2003, Journal of Biological Chemistry.
[24] T. Lithgow,et al. Mas37p, a novel receptor subunit for protein import into mitochondria , 1995, The Journal of cell biology.
[25] D. Kohda,et al. Structural Basis of Presequence Recognition by the Mitochondrial Protein Import Receptor Tom20 , 2000, Cell.
[26] D. Bedwell,et al. The amino terminus of the F1-ATPase beta-subunit precursor functions as an intramolecular chaperone to facilitate mitochondrial protein import , 1997, Molecular and cellular biology.
[27] W. Neupert,et al. Import of small Tim proteins into the mitochondrial intermembrane space , 2003, The EMBO journal.
[28] Ryan Lister,et al. The Mitochondrial Protein Import Machinery of Plants (MPIMP) database , 2003, Nucleic Acids Res..
[29] C. Leaver,et al. The adenine nucleotide translocator of higher plants is synthesized as a large precursor that is processed upon import into mitochondria. , 1992, The Plant journal : for cell and molecular biology.
[30] W. Neupert,et al. Biogenesis of Porin of the Outer Mitochondrial Membrane Involves an Import Pathway via Receptors and the General Import Pore of the Tom Complex , 2001, The Journal of cell biology.
[31] Thomas Meitinger,et al. MitoP2: the mitochondrial proteome database—now including mouse data , 2005, Nucleic Acids Res..
[32] F. Legeai,et al. Predotar: A tool for rapidly screening proteomes for N‐terminal targeting sequences , 2004, Proteomics.
[33] N. Pfanner,et al. An Essential Role of Sam50 in the Protein Sorting and Assembly Machinery of the Mitochondrial Outer Membrane* , 2003, Journal of Biological Chemistry.
[34] Z. Török,et al. Presequence-mediated intermembrane contact formation and lipid flow. A model membrane study. , 1994, Biochemistry.
[35] J. Whelan,et al. Mitochondrial protein import in plants – Signals, Sorting, Targeting, Processing and Regulation , 1998, Plant Molecular Biology.
[36] B. de Kruijff,et al. The importance of the amino terminus of the mitochondrial precursor protein apocytochrome c for translocation across model membranes. , 1989, The Journal of biological chemistry.
[37] A. Reichert,et al. Alternative topogenesis of Mgm1 and mitochondrial morphology depend on ATP and a functional import motor , 2004, The Journal of cell biology.
[38] P Vincens,et al. Computational method to predict mitochondrially imported proteins and their targeting sequences. , 1996, European journal of biochemistry.
[39] W. Neupert,et al. Biogenesis of Tom40, Core Component of the Tom Complex of Mitochondria , 1999, The Journal of cell biology.
[40] J. Hendrick,et al. Survey of amino-terminal proteolytic cleavage sites in mitochondrial precursor proteins: leader peptides cleaved by two matrix proteases share a three-amino acid motif. , 1989, Proceedings of the National Academy of Sciences of the United States of America.
[41] F. Hartl,et al. Mitochondrial protein import: Identification of processing peptidase and of PEP, a processing enhancing protein , 1988, Cell.
[42] W. Neupert,et al. Biogenesis of β-barrel membrane proteins of mitochondria , 2005 .
[43] F. Nóbrega,et al. BCS1, a novel gene required for the expression of functional Rieske iron‐sulfur protein in Saccharomyces cerevisiae. , 1992, The EMBO journal.
[44] C. Borner,et al. Characterization of the signal that directs Bcl-xL, but not Bcl-2, to the mitochondrial outer membrane , 2003, The Journal of cell biology.
[45] H. McBride,et al. Import and insertion of proteins into the mitochondrial outer membrane. , 1995, European journal of biochemistry.
[46] S. Colombo,et al. The tale of tail-anchored proteins , 2003, The Journal of cell biology.
[47] B. Dobberstein,et al. Transfer to proteins across membranes. II. Reconstitution of functional rough microsomes from heterologous components , 1975, The Journal of cell biology.
[48] V. Haucke,et al. Incomplete arrest in the outer membrane sorts NADH-cytochrome b5 reductase to two different submitochondrial compartments , 1994, Cell.
[49] N. Pfanner,et al. Chaperoning through the mitochondrial intermembrane space. , 2006, Molecular cell.
[50] N. Pfanner,et al. Multistep assembly of the protein import channel of the mitochondrial outer membrane , 2001, Nature Structural Biology.
[51] R. O. Poyton,et al. Overexpression of a leaderless form of yeast cytochrome c oxidase subunit Va circumvents the requirement for a leader peptide in mitochondrial import. , 1990, Molecular and cellular biology.
[52] J. Swanson,et al. Highly conserved charge-pair networks in the mitochondrial carrier family. , 1998, Journal of molecular biology.
[53] A. Reichert,et al. Processing of Mgm1 by the Rhomboid-type Protease Pcp1 Is Required for Maintenance of Mitochondrial Morphology and of Mitochondrial DNA* , 2003, Journal of Biological Chemistry.
[54] K. Dietmeier,et al. Differential Recognition of Preproteins by the Purified Cytosolic Domains of the Mitochondrial Import Receptors Tom20, Tom22, and Tom70* , 1997, The Journal of Biological Chemistry.
[55] D. Vetrie,et al. A novel X–linked gene, DDP, shows mutations in families with deafness (DFN–1), dystonia, mental deficiency and blindness , 1996, Nature Genetics.
[56] T. Pozzan,et al. Targeting GFP to organelles. , 1999, Methods in cell biology.
[57] H. Weiner,et al. Conversion of a Nonprocessed Mitochondrial Precursor Protein into One That Is Processed by the Mitochondrial Processing Peptidase (*) , 1995, The Journal of Biological Chemistry.
[58] N. Pfanner,et al. The cleavable presequence is not essential for import and assembly of the phosphate carrier of mammalian mitochondria but enhances the specificity and efficiency of import. , 1992, The Journal of biological chemistry.
[59] S. Branda,et al. Prediction and Identification of New Natural Substrates of the Yeast Mitochondrial Intermediate Peptidase (*) , 1995, The Journal of Biological Chemistry.
[60] R. Hallberg,et al. Cytochromes c 1 and b 2 are sorted to the intermembrane space of yeast mitochondria by a stop-transfer mechanism , 1992, Cell.
[61] G von Heijne,et al. Cleavage-site motifs in mitochondrial targeting peptides. , 1990, Protein engineering.
[62] P. Cavadini,et al. Mitochondrial processing peptidases. , 2002, Biochimica et biophysica acta.
[63] F. Hartl,et al. Successive translocation into and out of the mitochondrial matrix: Targeting of proteins to the intermembrane space by a bipartite signal peptide , 1987, Cell.
[64] W. Neupert,et al. The DNA Helicase, Hmi1p, Is Transported into Mitochondria by a C-terminal Cleavable Targeting Signal* , 1999, The Journal of Biological Chemistry.
[65] D. Mokranjac,et al. Tob38, a novel essential component in the biogenesis of β‐barrel proteins of mitochondria , 2004, EMBO reports.
[66] W. Neupert,et al. Recognition of preproteins by the isolated TOM complex of mitochondria , 2000, The EMBO journal.
[67] B. Guiard,et al. An internal targeting signal directing proteins into the mitochondrial intermembrane space. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[68] A. Millar,et al. The N-terminal cleavable extension of plant carrier proteins is responsible for efficient insertion into the inner mitochondrial membrane. , 2005, Journal of molecular biology.
[69] T. Lithgow,et al. The alpha and the beta: protein translocation across mitochondrial and plastid outer membranes. , 2001, Trends in biochemical sciences.
[70] T. Junne,et al. Cloning and disruption of the gene encoding yeast mitochondrial chaperonin 10, the homolog of E. coli groES , 1993, FEBS letters.
[71] G. Getz,et al. Import of Transcription Factor MTF1 into the Yeast Mitochondria Takes Place through an Unusual Pathway (*) , 1995, The Journal of Biological Chemistry.
[72] E. Schleiff,et al. Direct Membrane Insertion of Voltage-dependent Anion-selective Channel Protein Catalyzed by Mitochondrial Tom20 , 1999, The Journal of cell biology.
[73] Albert Sickmann,et al. The proteome of Saccharomyces cerevisiae mitochondria , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[74] B. Schönfisch,et al. Machinery for protein sorting and assembly in the mitochondrial outer membrane , 2003, Nature.
[75] C. Koehler,et al. How membrane proteins travel across the mitochondrial intermembrane space. , 1999, Trends in biochemical sciences.
[76] W. Neupert,et al. Internal targeting signal of the BCS1 protein: a novel mechanism of import into mitochondria. , 1996, The EMBO journal.
[77] W. Neupert,et al. Transport of the ADP/ATP carrier of mitochondria from the TOM complex to the TIM22·54 complex , 1999, The EMBO journal.
[78] G. Getz,et al. Import of Yeast Mitochondrial Transcription Factor (Mtf1p) via a Nonconventional Pathway* , 2002, The Journal of Biological Chemistry.
[79] Bradford W. Gibson,et al. Characterization of the human heart mitochondrial proteome , 2003, Nature Biotechnology.
[80] K. Mihara,et al. Characterization of the Signal That Directs Tom20 to the Mitochondrial Outer Membrane , 2000, The Journal of cell biology.
[81] M. Cumsky,et al. Localization of a synthetic presequence that blocks protein import into mitochondria. , 1990, The Journal of biological chemistry.
[82] K. Tokatlidis,et al. Juxtaposition of the Two Distal CX3C Motifs via Intrachain Disulfide Bonding Is Essential for the Folding of Tim10* , 2003, Journal of Biological Chemistry.
[83] E. Hurt,et al. The cleavable prepiece of an imported mitochondrial protein is sufficient to direct cytosolic dihydrofolate reductase into the mitochondrial matrix , 1984, FEBS letters.
[84] W. Neupert,et al. C‐ to N‐terminal translocation of preproteins into mitochondria , 1998, The EMBO journal.
[85] T. Lithgow,et al. A conserved proline residue is present in the transmembrane‐spanning domain of Tom7 and other tail‐anchored protein subunits of the TOM translocase , 2002, FEBS letters.
[86] Walter Neupert. Protein import into mitochondria. , 1997 .
[87] Meijia Yang,et al. The MAS-encoded processing protease of yeast mitochondria. Overproduction and characterization of its two nonidentical subunits. , 1990, The Journal of biological chemistry.
[88] E. Margoliash,et al. Amino acid sequence requirements for the association of apocytochrome c with mitochondria. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[89] E. Glaser,et al. Integration of the Mitochondrial-Processing Peptidase into the Cytochrome bc1 Complex in Plants , 1999, Journal of bioenergetics and biomembranes.
[90] W. Neupert,et al. Multiple functions of tail‐anchor domains of mitochondrial outer membrane proteins , 2003, FEBS letters.
[91] C. Koehler. The small Tim proteins and the twin Cx3C motif. , 2004, Trends in biochemical sciences.
[92] G. Schatz. Just follow the acid chain , 1997, Nature.
[93] A. Baker,et al. The mitochondrial targeting function of randomly generated peptide sequences correlates with predicted helical amphiphilicity. , 1989, The Journal of biological chemistry.
[94] J. Herrmann,et al. Chopped, trapped or tacked--protein translocation into the IMS of mitochondria. , 2005, Trends in biochemical sciences.
[95] G. Heijne. Mitochondrial targeting sequences may form amphiphilic helices. , 1986 .
[96] R. Frank. Spot-synthesis: an easy technique for the positionally addressable, parallel chemical synthesis on a membrane support , 1992 .
[97] M. Swaroop,et al. The general mitochondrial matrix processing protease from rat liver: structural characterization of the catalytic subunit. , 1990, Proceedings of the National Academy of Sciences of the United States of America.
[98] J. Schneider-Mergener,et al. Mitochondrial Protein Import: Recognition of Internal Import Signals of BCS1 by the TOM Complex , 2003, Molecular and Cellular Biology.
[99] D. Craik,et al. Solution Structure of the Acetylated and Noncleavable Mitochondrial Targeting Signal of Rat Chaperonin 10 (*) , 1995, The Journal of Biological Chemistry.
[100] E. Hurt,et al. The first twelve amino acids (less than half of the pre‐sequence) of an imported mitochondrial protein can direct mouse cytosolic dihydrofolate reductase into the yeast mitochondrial matrix. , 1985, The EMBO journal.
[101] Doron Rapaport,et al. Finding the right organelle , 2003, EMBO reports.
[102] K. Mihara,et al. Characterization of signal that directs C-tail-anchored proteins to mammalian mitochondrial outer membrane. , 2002, Molecular biology of the cell.
[103] A. Horwich,et al. A leader peptide is sufficient to direct mitochondrial import of a chimeric protein. , 1985, The EMBO journal.
[104] Z. Török,et al. The full length of a mitochondrial presequence is required for efficient monolayer insertion and interbilayer contact formation. , 1994, Molecular membrane biology.
[105] D. Winge,et al. Mutational Analysis of the Mitochondrial Copper Metallochaperone Cox17* , 2000, The Journal of Biological Chemistry.
[106] R. Sikorski,et al. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. , 1989, Genetics.
[107] W. Neupert,et al. A mutant of Neurospora crassa deficient in cytochrome c heme lyase activity cannot import cytochrome c into mitochondria. , 1988, The Journal of biological chemistry.
[108] D. Gorenstein,et al. 2D NMR and structural model for a mitochondrial signal peptide bound to a micelle. , 1990, Biochemistry.
[109] A. Kramer,et al. Synthesis and screening of peptide libraries on continuous cellulose membrane supports. , 1998, Methods in molecular biology.
[110] J. Richards,et al. A chemically synthesized pre‐sequence of an imported mitochondrial protein can form an amphiphilic helix and perturb natural and artificial phospholipid bilayers. , 1986, The EMBO journal.
[111] G. Heijne. Towards a comparative anatomy of N-terminal topogenic protein sequences , 1986 .
[112] D. Rapaport. Biogenesis of the mitochondrial TOM complex. , 2002, Trends in biochemical sciences.
[113] H. McBride,et al. A signal-anchor sequence selective for the mitochondrial outer membrane , 1992, The Journal of cell biology.
[114] D. Gorenstein,et al. Structure of the signal sequences for two mitochondrial matrix proteins that are not proteolytically processed upon import. , 1994, Biochemistry.
[115] J. Gamble,et al. A splice-isoform of vesicle-associated membrane protein-1 (VAMP-1) contains a mitochondrial targeting signal. , 1998, Molecular biology of the cell.