HPLC method for determination of in vitro delivery through and into porcine skin of adefovir (PMEA).
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[1] Shufeng Zhou,et al. Determination of adefovir in human plasma by liquid chromatography/tandem mass spectrometry: application to a pharmacokinetic study. , 2005, Rapid communications in mass spectrometry : RCM.
[2] J. Zbytovská,et al. Amphiphilic transdermal permeation enhancers: structure-activity relationships. , 2005, Current medicinal chemistry.
[3] M. Danta,et al. Adefovir dipivoxil: review of a novel acyclic nucleoside analogue , 2004, International journal of clinical practice.
[4] Christine R. Xu,et al. Ultra sensitive method for the determination of 9-(2-phosphonylmethoxyethyl)adenine in human serum by liquid chromatography-tandem mass spectrometry. , 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
[5] Fabio Garofolo,et al. Bioanalytical Method Validation , 2004 .
[6] E. De Clercq,et al. Transport, Uptake, and Metabolism of the Bis(pivaloyloxymethyl)-Ester Prodrug of 9-(2- Phosphonylmethoxyethyl)Adenine in an In Vitro Cell Culture System of the Intestinal Mucosa (Caco-2) , 1997, Pharmaceutical Research.
[7] K. A. Mattes,et al. Adefovir dipivoxil: a new antiviral agent for the treatment of hepatitis B virus infection. , 2003, Clinical therapeutics.
[8] S. Santoyo,et al. Optimization of topical cidofovir penetration using microparticles. , 2002, International journal of pharmaceutics.
[9] S. Santoyo,et al. Determination of cidofovir in both skin layers and percutaneous penetration samples by HPLC. , 2002, Journal of pharmaceutical and biomedical analysis.
[10] G. Boivin,et al. Herpes simplex virus isolates with reduced adefovir susceptibility selected in vivo by foscarnet therapy , 2002, Journal of medical virology.
[11] M. Magnani,et al. Erythrocyte-mediated delivery of a new homodinucleotide active against human immunodeficiency virus and herpes simplex virus. , 2001, The Journal of antimicrobial chemotherapy.
[12] A. Valentijn,et al. Novel hepatotrophic prodrugs of the antiviral nucleoside 9‐(2‐phosphonylmethoxyethyl)adenine with improved pharmacokinetics and antiviral activity , 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[13] J. Beijnen,et al. Improved and simplified liquid chromatographic assay for adefovir, a novel antiviral drug, in human plasma using derivatization with chloroacetaldehyde. , 1999, Journal of chromatography. B, Biomedical sciences and applications.
[14] J. Shaw,et al. Pharmacokinetics and metabolism of selected prodrugs of PMEA in rats. , 1997, Drug metabolism and disposition: the biological fate of chemicals.
[15] C. Perno,et al. Potent inhibition of human immunodeficiency virus and herpes simplex virus type 1 by 9-(2-phosphonylmethoxyethyl)adenine in primary macrophages is determined by drug metabolism, nucleotide pools, and cytokines. , 1996, Molecular pharmacology.
[16] E. De Clercq,et al. Antiviral activity of selected acyclic nucleoside analogues against human herpesvirus 6. , 1995, Antiviral research.
[17] A. Collier,et al. Clinical pharmacokinetics of adefovir in human immunodeficiency virus type 1-infected patients , 1995, Antimicrobial agents and chemotherapy.
[18] J. Shaw,et al. Oral, subcutaneous, and intramuscular bioavailabilities of the antiviral nucleotide analog 9-(2-phosphonylmethoxyethyl) adenine in cynomolgus monkeys , 1994, Antimicrobial Agents and Chemotherapy.
[19] E. De Clercq,et al. Efficacy of phosphonylmethoxyalkyl derivatives of adenine in experimental herpes simplex virus and vaccinia virus infections in vivo , 1989, Antimicrobial Agents and Chemotherapy.
[20] T. Franz. Percutaneous absorption on the relevance of in vitro data. , 1975, The Journal of investigative dermatology.