Deficiency Restricted to Mouse Hematopoietic Cells Causes an Age-and Sex-5 dependent Myelodysplastic Syndrome-Like Phenotype 6 7 8

1 2 3 4 Kdm6a Deficiency Restricted to Mouse Hematopoietic Cells Causes an Ageand Sex5 dependent Myelodysplastic Syndrome-Like Phenotype 6 7 8 Ling Tian1¶, Monique Chavez1¶, Gue Su Chang2, Nichole M. Helton1, Casey D.S. Katerndahl1, 9 Christopher A. Miller1,2, Lukas D. Wartman1*. 10 11 12 13 1Division of Oncology, Department of Internal Medicine, Washington University School of 14 Medicine, St Louis, MO 63110, USA 15 2McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO 63110 16 17 *Corresponding author: 18 E-mail: lwartman@wustl.edu 19 20

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