Bronchial damage and diffuse alveolar hemorrhage following chlorine gas inhalation: A case report.

Chlorine is a toxic inhalant and sources of exposure for individuals include accidental releases of chlorine vapor due to industrial or chemical transportation accidents. Inhalation of a large quantity of gas may cause circulatory and respiratory disorders or even mortality; however, the effects of a small amount of chlorine gas may be asymptomatic. The present case study presents a successfully treated 55-year-old male patient exposed to chlorine gas, resulting in bronchial damage and diffuse alveolar hemorrhage. Endobronchial and alveolar injuries were evaluated by direct observation using fiberoptic bronchoscopy (FB) and analyzing bronchoalveolar lavage fluid obtained by FB. Taking a precise medical history from the patient is crucial to correctly diagnose toxic gas inhalation. In addition, a timely and proper evaluation with chest imaging as well as FB may provide useful clinical information. Therefore, clinicians should consider performing FB if the circumstances permit.

[1]  Shinan Nie,et al.  Pneumomediastinum from acute inhalation of chlorine gas in 2 young patients. , 2011, The American journal of emergency medicine.

[2]  C. White,et al.  Chlorine gas inhalation: human clinical evidence of toxicity and experience in animal models. , 2010, Proceedings of the American Thoracic Society.

[3]  Z. Karakurt,et al.  Chlorine-induced extensive tracheobronchial necrosis concomitantly benzene-induced pancytopenia presented with severe pneumonia. , 2010, Tuberkuloz ve toraks.

[4]  C. Yıldırım,et al.  Myocardial infarction, acute ischemic stroke, and hyperglycemia triggered by acute chlorine gas inhalation. , 2009, The American journal of emergency medicine.

[5]  M. Ghanei,et al.  Late laryngeal findings in sulfur mustard poisoning , 2009, Clinical toxicology.

[6]  N. Aikawa,et al.  Two cases of delayed-onset acute lung injury after chlorine gas exposure , 2009 .

[7]  G. Sharma,et al.  Acute Respiratory Distress Syndrome From Chlorine Inhalation During a Swimming Pool Accident: A Case Report and Review of the Literature , 2008, Journal of intensive care medicine.

[8]  M. Forrester,et al.  Pattern of chlorine gas exposures reported to Texas poison control centers, 2000 through 2005. , 2008, Texas medicine.

[9]  G. Hoyle,et al.  Acute lung injury induced by chlorine inhalation in C57BL/6 and FVB/N mice. , 2008, Inhalation toxicology.

[10]  J. Kanne,et al.  Trauma cases from Harborview Medical Center. Airway injury after acute chlorine exposure. , 2006, AJR. American journal of roentgenology.

[11]  L. Cancio,et al.  Acute respiratory distress syndrome secondary to inhalation of chlorine gas in sheep. , 2006, The Journal of trauma.

[12]  D. Pierson,et al.  Acute inhalation injury with evidence of diffuse bronchiolitis following chlorine gas exposure at a swimming pool. , 2004, Respiratory care.

[13]  C Winder,et al.  The toxicology of chlorine. , 2001, Environmental research.

[14]  K. Kilburn Chlorine-Induced Damage Documented by Neurophysiological, Neuropsychological, and Pulmonary Testing , 2000, Archives of environmental health.

[15]  J. Malo,et al.  Longitudinal assessment of airway caliber and responsiveness in workers exposed to chlorine. , 1999, American journal of respiratory and critical care medicine.

[16]  J. Sexton,et al.  Chlorine inhalation: the big picture. , 1998, Journal of toxicology. Clinical toxicology.

[17]  M. FitzGerald,et al.  Reactive Airways Dysfunction Syndrome (RADS) due to chlorine gas exposure , 1990, Irish journal of medical science.

[18]  D. Schwartz,et al.  The pulmonary sequelae associated with accidental inhalation of chlorine gas. , 1990, Chest.

[19]  M. A. Cohen,et al.  Inhalation of products of combustion. , 1983, Annals of emergency medicine.