A High-Calcium and Phosphate Rescue Diet and VDR-Expressing Transgenes Normalize Serum Vitamin D Metabolite Profiles and Renal Cyp27b1 and Cyp24a1 Expression in VDR Null Mice.
暂无分享,去创建一个
[1] J. Pike,et al. The vitamin D receptor functions as a transcription regulator in the absence of 1,25-dihydroxyvitamin D3 , 2016, The Journal of Steroid Biochemistry and Molecular Biology.
[2] H. DeLuca,et al. 1,25-Dihydroxyvitamin D3 Controls a Cohort of Vitamin D Receptor Target Genes in the Proximal Intestine That Is Enriched for Calcium-regulating Components* , 2015, The Journal of Biological Chemistry.
[3] J. Goellner,et al. A DNA Segment Spanning the Mouse Tnfsf11 Transcription Unit and Its Upstream Regulatory Domain Rescues the Pleiotropic Biologic Phenotype of the RANKL Null Mouse , 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[4] D. Moras,et al. A vitamin D receptor selectively activated by gemini analogs reveals ligand dependent and independent effects. , 2015, Cell reports.
[5] J. Goellner,et al. A humanized mouse model of hereditary 1,25-dihydroxyvitamin D-resistant rickets without alopecia. , 2014, Endocrinology.
[6] J. Goellner,et al. Mouse and human BAC transgenes recapitulate tissue-specific expression of the vitamin D receptor in mice and rescue the VDR-null phenotype. , 2014, Endocrinology.
[7] H. DeLuca,et al. Clinical utility of simultaneous quantitation of 25-hydroxyvitamin D and 24,25-dihydroxyvitamin D by LC-MS/MS involving derivatization with DMEQ-TAD. , 2014, The Journal of clinical endocrinology and metabolism.
[8] W. Kuebler,et al. Vitamin D is a regulator of endothelial nitric oxide synthase and arterial stiffness in mice. , 2014, Molecular endocrinology.
[9] H. DeLuca,et al. CYP2R1 is a major, but not exclusive, contributor to 25-hydroxyvitamin D production in vivo , 2013, Proceedings of the National Academy of Sciences.
[10] J. Fleet,et al. Villin promoter‐mediated transgenic expression of transient receptor potential cation channel, subfamily V, member 6 (TRPV6) increases intestinal calcium absorption in wild‐type and vitamin D receptor knockout mice , 2012, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[11] Glenville Jones,et al. 25-Hydroxyvitamin D-24-hydroxylase (CYP24A1): its important role in the degradation of vitamin D. , 2012, Archives of biochemistry and biophysics.
[12] R. St-Arnaud,et al. Vitamin D metabolism, cartilage and bone fracture repair , 2011, Molecular and Cellular Endocrinology.
[13] J. Pike,et al. Genome-wide principles of gene regulation by the vitamin D receptor and its activating ligand , 2011, Molecular and Cellular Endocrinology.
[14] Glenville Jones,et al. Bioengineering Anabolic Vitamin D-25-Hydroxylase Activity into the Human Vitamin D Catabolic Enzyme, Cytochrome P450 CYP24A1, by a V391L Mutation* , 2011, The Journal of Biological Chemistry.
[15] M. Haussler,et al. Vitamin D Receptor: Key Roles in Bone Mineral Pathophysiology, Molecular Mechanism of Action, and Novel Nutritional Ligands , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[16] C. Kovacs,et al. The vitamin D receptor is not required for fetal mineral homeostasis or for the regulation of placental calcium transfer in mice. , 2005, American journal of physiology. Endocrinology and metabolism.
[17] C. Carlberg,et al. A structural basis for the species-specific antagonism of 26,23-lactones on vitamin D signaling. , 2004, Chemistry & biology.
[18] S. Kato,et al. Metastatic growth of lung cancer cells is extremely reduced in Vitamin D receptor knockout mice , 2004, The Journal of Steroid Biochemistry and Molecular Biology.
[19] D. Miao,et al. Inactivation of the 25-Hydroxyvitamin D 1α-Hydroxylase and Vitamin D Receptor Demonstrates Independent and Interdependent Effects of Calcium and Vitamin D on Skeletal and Mineral Homeostasis* , 2004, Journal of Biological Chemistry.
[20] Wei Zheng,et al. Altered gene expression profile in the kidney of vitamin D receptor knockout mice , 2003, Journal of cellular biochemistry.
[21] S. Kato,et al. Vitamin D receptor (VDR) knockout mice reveal VDR-independent regulation of intestinal calcium absorption and ECaC2 and calbindin D9k mRNA. , 2003, The Journal of nutrition.
[22] R. Balling,et al. Deletion of deoxyribonucleic acid binding domain of the vitamin D receptor abrogates genomic and nongenomic functions of vitamin D. , 2002, Molecular endocrinology.
[23] H. DeLuca,et al. Parathyroid hormone regulates 25-hydroxyvitamin D3-24-hydroxylase mRNA by altering its stability , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[24] P. Carmeliet,et al. Duodenal calcium absorption in vitamin D receptor–knockout mice: Functional and molecular aspects , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[25] K. Inouye,et al. Dual metabolic pathway of 25-hydroxyvitamin D3 catalyzed by human CYP24. , 2000, European journal of biochemistry.
[26] S. Kato,et al. Positive and Negative Regulations of the Renal 25-Hydroxyvitamin D3 1α-Hydroxylase Gene by Parathyroid Hormone, Calcitonin, and 1α,25(OH)2D3 in Intact Animals. , 1999, Endocrinology.
[27] H. DeLuca,et al. Current understanding of the molecular actions of vitamin D. , 1998, Physiological reviews.
[28] R. Baron,et al. Normalization of mineral ion homeostasis by dietary means prevents hyperparathyroidism, rickets, and osteomalacia, but not alopecia in vitamin D receptor-ablated mice. , 1998, Endocrinology.
[29] R. Baron,et al. Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[30] Tatsuya Yoshizawa,et al. Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning , 1997, Nature Genetics.
[31] 西村篤. Regulation of Messenger Ribonucleic Acid Expression of 1α,25-Dihydroxyvitamin D3-24-Hydroxylase in Rat Osteoblasts(骨芽細胞における1α,25-ジヒドロキシビタミンD3-24-水酸化酵素mRNAの発現調節) , 1996 .
[32] M. Noshiro,et al. Regulation of messenger ribonucleic acid expression of 1 alpha,25-dihydroxyvitamin D3-24-hydroxylase in rat osteoblasts. , 1994, Endocrinology.
[33] M. Noshiro,et al. Parathyroid hormone inhibits 25-hydroxyvitamin D3-24-hydroxylase mRNA expression stimulated by 1 alpha,25-dihydroxyvitamin D3 in rat kidney but not in intestine. , 1992, The Journal of biological chemistry.
[34] M. Noshiro,et al. Cloning and expression of cDNA encoding 25‐hydroxyvitamin D3 24‐hydroxylase , 1991, FEBS letters.
[35] R. Horst,et al. Parathyroid hormone down-regulates 1,25-dihydroxyvitamin D receptors (VDR) and VDR messenger ribonucleic acid in vitro and blocks homologous up-regulation of VDR in vivo. , 1990, Endocrinology.
[36] Glenville Jones,et al. 1,25‐dihydroxyvitamin D3 metabolism in a human osteosarcoma cell line and human bone cells , 1990, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[37] H. DeLuca,et al. Rat renal 25-hydroxyvitamin D3 1- and 24-hydroxylases: their in vivo regulation. , 1984, The American journal of physiology.
[38] H. DeLuca,et al. 25-Hydroxyvitamin D3 26,23-lactone: a new in vivo metabolite of vitamin D. , 1979, Biochemistry.
[39] R. Horst,et al. 25-OHD3-26,23-lactone: a metabolite of vitamin D3 that is 5 times more potent than 25-OHD3 in the rat plasma competitive protein binding radioassay. , 1979, Biochemical and biophysical research communications.