Evaluation of Pulse‐Width of Spinal Nerve Stimulation in a Rat Model of Bladder Micturition Reflex

The spinal nerve stimulation (SNS) evoked motor threshold (Tmot) response across different pulse‐widths (PWs) was first explored and a subset of selected stimulation PWs were further assessed with respect to bladder reflex contraction (BRC).

[1]  J. B. Ranck,et al.  Which elements are excited in electrical stimulation of mammalian central nervous system: A review , 1975, Brain Research.

[2]  C. Li,et al.  Excitability characteristics of the A- and C-fibers in a peripheral nerve , 1976, Experimental Neurology.

[3]  J. Mortimer,et al.  The Effect of Stimulus Parameters on the Recruitment Characteristics of Direct Nerve Stimulation , 1983, IEEE Transactions on Biomedical Engineering.

[4]  R. Schmidt,et al.  Electrical stimulation in the clinical management of the neurogenic bladder. , 1988, The Journal of urology.

[5]  A. Angel,et al.  Central neuronal pathways and the process of anaesthesia. , 1993, British journal of anaesthesia.

[6]  Warren M. Grill,et al.  Stimulus waveforms for selective neural stimulation , 1995 .

[7]  W. Grill,et al.  The effect of stimulus pulse duration on selectivity of neural stimulation , 1996, IEEE Transactions on Biomedical Engineering.

[8]  G. Gebhart,et al.  Effects of opioids on mechanosensitive pelvic nerve afferent fibers innervating the urinary bladder of the rat. , 1997, Journal of neurophysiology.

[9]  J. Bullier,et al.  Axons, but not cell bodies, are activated by electrical stimulation in cortical gray matter II. Evidence from selective inactivation of cell bodies and axon initial segments , 1998, Experimental Brain Research.

[10]  H. de Bruin,et al.  The effect of stimulus current pulse width on nerve fiber size recruitment patterns. , 1999, Medical engineering & physics.

[11]  M. Craggs,et al.  Studies of the latency of pelvic floor contraction during peripheral nerve evaluation show that the muscle response is reflexly mediated. , 2000, The Journal of urology.

[12]  L. Baert,et al.  Patient Satisfaction and Complications Following Sacral Nerve Stimulation for Urinary Retention, Urge Incontinence and Perineal Pain: a Multicenter Evaluation , 2000, International Urogynecology Journal.

[13]  William C. de Groat,et al.  Histological and Electrical Properties of Rat Dorsal Root Ganglion Neurons Innervating the Lower Urinary Tract , 2003, The Journal of Neuroscience.

[14]  M. McLennan The role of electrodiagnostic techniques in the reprogramming of patients with a delayed suboptimal response to sacral nerve stimulation , 2003, International Urogynecology Journal.

[15]  C. Maggi,et al.  Suitability of urethane anesthesia for physiopharmacological investigations in various systems Part 1: General considerations , 1986, Experientia.

[16]  Brian L. Cohen,et al.  Predictors of success for first stage neuromodulation: motor versus sensory response. , 2006, The Journal of urology.

[17]  S. Harrison,et al.  Neuromodulation for Lower Urinary Tract Dysfunction – An Update , 2007, TheScientificWorldJournal.

[18]  J. Hieble,et al.  An excitatory role for peripheral EP3 receptors in bladder afferent function. , 2008, American journal of physiology. Renal physiology.

[19]  W. Grill,et al.  Effects of stimulation site and stimulation parameters on bladder inhibition by electrical nerve stimulation , 2012, BJU international.

[20]  D. Nelson,et al.  Neuromodulation in a rat model of the bladder micturition reflex. , 2012, American journal of physiology. Renal physiology.

[21]  D. Nelson,et al.  Quantification of effectiveness of bilateral and unilateral neuromodulation in the rat bladder rhythmic contraction model , 2013, BMC Urology.

[22]  K. Osann,et al.  Comparison of Motor and Sensory Response of InterStim® for Overactive Bladder Syndrome , 2013, Female pelvic medicine & reconstructive surgery.

[23]  J. Roppolo,et al.  Neural pathways involved in sacral neuromodulation of reflex bladder activity in cats. , 2013, American journal of physiology. Renal physiology.

[24]  K. Peters,et al.  Effect of Sacral Neuromodulation Rate on Overactive Bladder Symptoms: A Randomized Crossover Feasibility Study , 2013, Lower urinary tract symptoms.

[25]  Andres Y. Agudelo-Toro,et al.  Chronaxie Measurements in Patterned Neuronal Cultures from Rat Hippocampus , 2015, PloS one.

[26]  D. Nelson,et al.  Optimization of Neuromodulation for Bladder Control in a Rat Cystitis Model , 2016, Neuromodulation : journal of the International Neuromodulation Society.

[27]  C. Comiter,et al.  Three-year Follow-up Results of a Prospective, Multicenter Study in Overactive Bladder Subjects Treated With Sacral Neuromodulation. , 2016, Urology.