Conversation Analysis (CA) as a mode of inquiry is addressed to all forms of talk and other conduct in interaction, and, accordingly, touches on the concerns of applied linguists at many points. This review sketches and offers bibliographical guidance on several of the major relevant areas of conversation-analytic work—turn-taking, repair, and word selection—and indicates past or potential points of contact with applied linguistics. After covering these areas, we include a brief discussion of some key themes in CA's treatment of talk in institutional contexts. Finally, we discuss several established areas of applied linguistic work in which conversation analytic work is being explored—native, nonnative, and multilingual talk; talk in educational institutions; grammar and interaction; intercultural communication and comparative CA; and implications for designing language teaching tasks, materials, and assessment tasks. We end with some cautions on applying CA findings to other applied linguistic research contexts.