Non-invasive home mechanical ventilation: effectiveness and efficiency of an outpatient initiation protocol compared with the standard in-hospital model.

OBJECTIVE To compare the effectiveness and efficiency of an initiation protocol for non-invasive home mechanical ventilation (NIHMV) carried out at a pulmonary outpatient clinic with the standard in-hospital model. METHODS Prospective, observational study. POPULATION 16 patients divided into two groups: (A) outpatient protocol (n=9); and (B) standard in-hospital initiation with an elective admission (n=7). INSTRUMENTATION at baseline condition and treatment starting, arterial blood gases and nocturnal pulse-oximetry were performed. At the end of follow-up, arterial blood gases and patient compliance (ventilator's built-in counter) was determined. Efficiency was evaluated by calculating cost savings per ventilated patient for the financier and accumulated days of hospitalization saved. RESULTS No differences in baseline conditions were observed. Ventilation was effective in the two groups: a significant decrease in PaCO(2) and an increase in mean nocturnal oxygen saturation were observed after initiating ventilation. (Group A: PaCO(2):42.9+/-1.5; SpO(2):91.9+/-1.9; Group B:PaCO(2):44.3+/-6; SpO(2):91.9+/-2.7). At three months the effectiveness of ventilation and the number of hours of ventilation was equivalent in all groups. The new model cut costs for the health care financier by 50%. The outpatient sessions saved 63 days of hospitalization. CONCLUSIONS (1) Outpatient initiation is an effective and efficient alternative to the traditional in-hospital method for NIHMV. (2) The outpatient protocol represents a substantial saving for the financier.

[1]  B. Celli,et al.  Long-term controlled trial of nocturnal nasal positive pressure ventilation in patients with severe COPD. , 2000, Chest.

[2]  J. Gravil,et al.  Home treatment of exacerbations of chronic obstructive pulmonary disease by an acute respiratory assessment service , 1998, The Lancet.

[3]  I. Smith,et al.  Domiciliary-assisted ventilation in patients with myotonic dystrophy. , 2002, Chest.

[4]  V. O. Rubio,et al.  Chronic Saturation of Emergency Departments: They Should Not Be Flooded by Patients With Chronic Diseases , 2006 .

[5]  B. Midgren,et al.  The effects of nocturnal home mechanical ventilation on daytime blood gas disturbances , 2006, Clinical physiology and functional imaging.

[6]  Grupo de Trabajo de la Separ,et al.  Normativa para la práctica de la espirometría forzada , 1989 .

[7]  C. Sullivan,et al.  Effects of long-term nocturnal nasal ventilation on spontaneous breathing during sleep in neuromuscular and chest wall disorders. , 1996, The European respiratory journal.

[8]  G. Criner,et al.  Efficacy and compliance with noninvasive positive pressure ventilation in patients with chronic respiratory failure. , 1999, Chest.

[9]  R. Rodriguez-Roisin Normativa sobre la gasometría arterial , 1998 .

[10]  J. Chevrolet,et al.  Changing patterns in long-term noninvasive ventilation: a 7-year prospective study in the Geneva Lake area. , 2003, Chest.

[11]  A. Corrado,et al.  The Italian multicentre study on noninvasive ventilation in chronic obstructive pulmonary disease patients , 2002, European Respiratory Journal.

[12]  S. Díaz-Lobato,et al.  Reflexiones para la organización y desarrollo de una unidad de ventilación mecánica no invasiva y domiciliaria , 2005 .

[13]  J. Escarrabill,et al.  Survival in amyotrophic lateral sclerosis with home mechanical ventilation: the impact of systematic respiratory assessment and bulbar involvement. , 2005, Chest.

[14]  Ch. Domingo,et al.  Efectividad y eficiencia de una consulta monográfica hospitalaria para pacientes con EPOC e insuficiencia respiratoria , 2006 .

[15]  V. Rubio,et al.  Urgencias hospitalarias o colapso crnico: los pacientes crnicos no deberan colapsar urgencias , 2006 .

[16]  G. Laier-Groeneveld,et al.  Infrastructure, funding and follow-up in a programme of noninvasive ventilation , 2002, European Respiratory Journal.

[17]  Ch Domingo,et al.  [Effectiveness and efficiency of a specialized unit in the care of patients with chronic obstructive pulmonary disease and respiratory insufficiency]. , 2006, Archivos de bronconeumologia.

[18]  D. Navajas,et al.  Spirometric reference values from a Mediterranean population. , 1986, Bulletin europeen de physiopathologie respiratoire.

[19]  A. Moreno,et al.  [Transcutaneous measurement of partial pressure of carbon dioxide and oxygen saturation: validation of the SenTec monitor]. , 2006, Archivos de bronconeumologia.

[20]  R. Millman,et al.  Nocturnal positive-pressure ventilation via nasal mask in patients with severe chronic obstructive pulmonary disease. , 1991, The American review of respiratory disease.

[21]  S. Díaz-Lobato,et al.  [Setting up and organizing a noninvasive ventilation unit for hospital and home therapy]. , 2005, Archivos de bronconeumologia.

[22]  P. Jones,et al.  Nasal pressure support ventilation plus oxygen compared with oxygen therapy alone in hypercapnic COPD. , 1995, American journal of respiratory and critical care medicine.