Costimulation blockade of both inducible costimulator and CD40 ligand induces dominant tolerance to islet allografts and prevents spontaneous autoimmune diabetes in the NOD mouse.
暂无分享,去创建一个
A. Shapiro | W. Hancock | R. Pawlick | S. Nanji | C. Anderson | B. Luo | Lin‐Fu Zhu | Colleen D. Schur
[1] D. Zélénika,et al. Induction of foxP3+ Regulatory T Cells in the Periphery of T Cell Receptor Transgenic Mice Tolerized to Transplants1 , 2004, The Journal of Immunology.
[2] A. M. Shapiro,et al. Multiple Combination Therapies Involving Blockade of ICOS/B7RP‐1 Costimulation Facilitate Long‐Term Islet Allograft Survival , 2004, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[3] A. Shapiro,et al. Combination therapy with anti-ICOS and cyclosporine enhances cardiac but not islet allograft survival. , 2003, Transplantation proceedings.
[4] E. Simpson,et al. Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade , 2003, Nature Medicine.
[5] Wenda Gao,et al. Stimulating PD-1–negative signals concurrent with blocking CD154 co-stimulation induces long-term islet allograft survival1 , 2003, Transplantation.
[6] G. Freeman,et al. The role of the ICOS-B7h T cell costimulatory pathway in transplantation immunity. , 2003, The Journal of clinical investigation.
[7] M. Sayegh,et al. Interaction Between ICOS‐B7RP1 and B7‐CD28 Costimulatory Pathways in Alloimmune Responses In Vivo , 2003, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[8] T. Nomura,et al. Control of Regulatory T Cell Development by the Transcription Factor Foxp3 , 2002 .
[9] 中村 嘉一郎. Acceptance of islet allografts in the liver of mice by blockade of an inducible costimulator , 2003 .
[10] R. Gill,et al. CD4-Dependent Generation of Dominant Transplantation Tolerance Induced by Simultaneous Perturbation of CD154 and LFA-1 Pathways1 , 2002, The Journal of Immunology.
[11] H. Waldmann,et al. Identification of Regulatory T Cells in Tolerated Allografts , 2002, The Journal of experimental medicine.
[12] M. Makuuchi,et al. Prolonged survival in rat liver transplantation with mouse monoclonal antibody against an inducible costimulator (ICOS)1 , 2002, Transplantation.
[13] Mary Collins,et al. The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses. , 2002, Annual review of immunology.
[14] J. Gutiérrez-Ramos,et al. Importance of ICOS–B7RP-1 costimulation in acute and chronic allograft rejection , 2001, Nature Immunology.
[15] J. Gutiérrez-Ramos,et al. The costimulatory molecule ICOS plays an important role in the immunopathogenesis of EAE , 2001, Nature Immunology.
[16] J. Bluestone,et al. ICOS costimulation: it's not just for TH2 cells anymore , 2001, Nature Immunology.
[17] H. Waldmann,et al. Regulating the immune response to transplants. a role for CD4+ regulatory cells? , 2001, Immunity.
[18] C. Orosz,et al. Immunobiology of Allograft Rejection in the Absence of IFN-γ: CD8+ Effector Cells Develop Independently of CD4+ Cells and CD40-CD40 Ligand Interactions1 , 2001, The Journal of Immunology.
[19] R. Colvin,et al. Costimulatory blockade for induction of mixed chimerism and renal allograft tolerance in nonhuman primates. , 2001, Transplantation proceedings.
[20] J. Allison,et al. ICOS co-stimulatory receptor is essential for T-cell activation and function , 2001, Nature.
[21] C. Ariyan,et al. Targeting Signal 1 Through CD45RB Synergizes with CD40 Ligand Blockade and Promotes Long Term Engraftment and Tolerance in Stringent Transplant Models1 , 2001, The Journal of Immunology.
[22] G. Freeman,et al. Mouse Inducible Costimulatory Molecule (ICOS) Expression Is Enhanced by CD28 Costimulation and Regulates Differentiation of CD4+ T Cells1 , 2000, The Journal of Immunology.
[23] H. Waldmann,et al. Cutting Edge: Anti-CD154 Therapeutic Antibodies Induce Infectious Transplantation Tolerance1 , 2000, The Journal of Immunology.
[24] O. Witzke,et al. CD40-CD40 Ligand-Independent Activation of CD8+ T Cells Can Trigger Allograft Rejection1 , 2000, The Journal of Immunology.
[25] C. Anderson,et al. Danger: the view from the bottom of the cliff. , 2000, Seminars in immunology.
[26] M. Sykes,et al. Allogeneic bone marrow transplantation with co-stimulatory blockade induces macrochimerism and tolerance without cytoreductive host treatment , 2000, Nature Medicine.
[27] C. Larsen,et al. Asialo GM1(+) CD8(+) T cells play a critical role in costimulation blockade-resistant allograft rejection. , 1999, The Journal of clinical investigation.
[28] H. Waldmann,et al. CD40 ligand blockade induces CD4+ T cell tolerance and linked suppression. , 1999, Journal of immunology.
[29] T. Strom,et al. Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance , 1999, Nature Medicine.
[30] D. Harlan,et al. Long-term survival and function of intrahepatic islet allografts in baboons treated with humanized anti-CD154. , 1999, Diabetes.
[31] D. Harlan,et al. Treatment with humanized monoclonal antibody against CD154 prevents acute renal allograft rejection in nonhuman primates , 1999, Nature Medicine.
[32] T. Strom,et al. Induce Allograft Tolerance with Combined CTLA 4 Signals Are Required to Optimally , 1999 .
[33] R. Noelle,et al. Long-term survival of skin allografts induced by donor splenocytes and anti-CD154 antibody in thymectomized mice requires CD4(+) T cells, interferon-gamma, and CTLA4. , 1998, The Journal of clinical investigation.
[34] R. Flavell,et al. CD40 and CD154 in cell-mediated immunity. , 1998, Annual review of immunology.
[35] R. Tisch,et al. CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice. , 1997, Journal of immunology.
[36] J Bajorath,et al. Immune regulation by CD40 and its ligand GP39. , 1996, Annual review of immunology.
[37] R. Noelle,et al. Survival of mouse pancreatic islet allografts in recipients treated with allogeneic small lymphocytes and antibody to CD40 ligand. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[38] J. Sprent,et al. Split tolerance in spleen chimeras. , 1995, Journal of immunology.
[39] C. Schlachta,et al. Improved techniques for kidney transplantation in mice , 1995, Microsurgery.
[40] R. Gill,et al. Tolerance induction to cultured islet allografts. I. Characterization of the tolerant state. , 1994, Transplantation.
[41] R. Gill,et al. Tolerance induction to cultured islet allografts. II. The status of antidonor reactivity in tolerant animals. , 1994, Transplantation.
[42] J. Markmann,et al. Islet allograft, islet xenograft, and skin allograft survival in CD8+ T lymphocyte-deficient mice. , 1993, Transplantation.
[43] P. Matzinger. The JAM test. A simple assay for DNA fragmentation and cell death. , 1991, Journal of immunological methods.
[44] A. Monaco,et al. An improved method for isolation of mouse pancreatic islets. , 1985, Transplantation.
[45] R. Lechler,et al. The question as to why major histocompatibility complex (MHC) a antigens are uniquely powerful primary immunogens and in this respect differ from antigens of the minor systems , 2003 .
[46] P. Lacy,et al. Method for the Isolation of Intact Islets of Langerhans from the Rat Pancreas , 1967, Diabetes.