KIF14 promotes proliferation, lymphatic metastasis and chemoresistance through G3BP1/YBX1 mediated NF-κB pathway in cholangiocarcinoma

[1]  T. Han,et al.  Promotion of gastric tumor initiating cells in a 3D collagen gel culture model via YBX1/SPP1/NF-κB signaling , 2021, Cancer cell international.

[2]  J. Yeh,et al.  GM-CSF drives myelopoiesis, recruitment and polarisation of tumour-associated macrophages in cholangiocarcinoma and systemic blockade facilitates antitumour immunity , 2021, Gut.

[3]  Lixia Xu,et al.  N7-Methylguanosine tRNA modification enhances oncogenic mRNA translation and promotes intrahepatic cholangiocarcinoma progression. , 2021, Molecular cell.

[4]  F. Gao,et al.  Orf Virus ORF120 Protein Positively Regulates the NF-κB Pathway by Interacting with G3BP1 , 2021, Journal of virology.

[5]  Zhenfeng Zhang,et al.  Tumor-derived lactate inhibit the efficacy of lenvatinib through regulating PD-L1 expression on neutrophil in hepatocellular carcinoma , 2021, Journal for ImmunoTherapy of Cancer.

[6]  Ke Chen,et al.  Flightless I Homolog Reverses Enzalutamide Resistance through PD-L1–Mediated Immune Evasion in Prostate Cancer , 2021, Cancer Immunology Research.

[7]  Jia Fan,et al.  Tumor-associated neutrophils and macrophages interaction contributes to intrahepatic cholangiocarcinoma progression by activating STAT3 , 2021, Journal for ImmunoTherapy of Cancer.

[8]  R. Jain,et al.  Placental growth factor promotes tumour desmoplasia and treatment resistance in intrahepatic cholangiocarcinoma , 2021, Gut.

[9]  Xuehao Wang,et al.  BUB1B promotes extrahepatic cholangiocarcinoma progression via JNK/c-Jun pathways , 2021, Cell death & disease.

[10]  A. Asenjo,et al.  Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14 , 2020, Nature Communications.

[11]  Hui Liu,et al.  KIF15-Mediated Stabilization of AR and AR-V7 Contributes to Enzalutamide Resistance in Prostate Cancer , 2020, Cancer Research.

[12]  P. Rodrigues,et al.  Pathogenesis of Cholangiocarcinoma. , 2020, Annual review of pathology.

[13]  Xing Wu,et al.  KIF14 and KIF23 Promote Cell Proliferation and Chemoresistance in HCC Cells, and Predict Worse Prognosis of Patients with HCC , 2020, Cancer management and research.

[14]  B. Zhai,et al.  Silencing KIF14 reverses acquired resistance to sorafenib in hepatocellular carcinoma , 2020, Aging.

[15]  Xuehao Wang,et al.  Camrelizumab plus gemcitabine and oxaliplatin (GEMOX) in patients with advanced biliary tract cancer: a single-arm, open-label, phase II trial , 2020, Journal for ImmunoTherapy of Cancer.

[16]  B. Wollenberg,et al.  Recurrent HNSCC Harbor an Immunosuppressive Tumor Immune Microenvironment Suggesting Successful Tumor Immune Evasion , 2020, Clinical Cancer Research.

[17]  S. Di Marco,et al.  G3BP1 controls the senescence-associated secretome and its impact on cancer progression , 2020, Nature Communications.

[18]  Yunlong Liu,et al.  PRMT5-mediated methylation of YBX1 regulates NF-κB activity in colorectal cancer , 2020, Scientific Reports.

[19]  L. Deterding,et al.  HNF4α regulates sulfur amino acid metabolism and confers sensitivity to methionine restriction in liver cancer , 2020, Nature Communications.

[20]  M. Smyth,et al.  The NK cell–cancer cycle: advances and new challenges in NK cell–based immunotherapies , 2020, Nature Immunology.

[21]  A. Ashworth,et al.  HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer , 2020, Cell reports.

[22]  Alexandre Benmerah,et al.  KIF14 controls ciliogenesis via regulation of Aurora A and is important for Hedgehog signaling , 2020, The Journal of cell biology.

[23]  T. Tuschl,et al.  The G3BP1-Family-USP10 Deubiquitinase Complex Rescues Ubiquitinated 40S Subunits of Ribosomes Stalled in Translation from Lysosomal Degradation. , 2020, Molecular cell.

[24]  Zhu Wang,et al.  Nuclear receptor HNF4α performs a tumor suppressor function in prostate cancer via its induction of p21-driven cellular senescence , 2019, Oncogene.

[25]  Hongmei Zheng,et al.  Elevated expression of G3BP1 associates with YB1 and p‐AKT and predicts poor prognosis in nonsmall cell lung cancer patients after surgical resection , 2019, Cancer medicine.

[26]  Qiqi Cui,et al.  The interaction of YBX1 with G3BP1 promotes renal cell carcinoma cell metastasis via YBX1/G3BP1-SPP1- NF-κB signaling axis , 2019, Journal of Experimental & Clinical Cancer Research.

[27]  M. Borad,et al.  Gemcitabine, Cisplatin, and nab-Paclitaxel for the Treatment of Advanced Biliary Tract Cancers: A Phase 2 Clinical Trial. , 2019, JAMA oncology.

[28]  D. Kuang,et al.  Targeting the YB-1/PD-L1 Axis to Enhance Chemotherapy and Antitumor Immunity , 2019, Cancer Immunology Research.

[29]  A. Chinnaiyan,et al.  CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy , 2019, Nature.

[30]  A. Chinnaiyan,et al.  CD8+ T cells regulate tumor ferroptosis during cancer immunotherapy , 2019, Nature.

[31]  Yingli Wu,et al.  KIF14 promotes tumor progression and metastasis and is an independent predictor of poor prognosis in human gastric cancer. , 2019, Biochimica et biophysica acta. Molecular basis of disease.

[32]  Zaozao Wang,et al.  KIF14 promotes cell proliferation via activation of Akt and is directly targeted by miR-200c in colorectal cancer , 2018, International journal of oncology.

[33]  G. Yip,et al.  Kinesin superfamily: roles in breast cancer, patient prognosis and therapeutics , 2018, Oncogene.

[34]  M. Karin,et al.  NF-κB, inflammation, immunity and cancer: coming of age , 2018, Nature Reviews Immunology.

[35]  T. Ishiko,et al.  Tumour-infiltrating inflammatory and immune cells in patients with extrahepatic cholangiocarcinoma , 2017, British Journal of Cancer.

[36]  F. Alkuraya,et al.  Mutations of KIF14 cause primary microcephaly by impairing cytokinesis , 2017, Annals of neurology.

[37]  Ruowen Sun,et al.  Silencing of Y-box binding protein-1 by RNA interference inhibits proliferation, invasion, and metastasis, and enhances sensitivity to cisplatin through NF-κB signaling pathway in human neuroblastoma SH-SY5Y cells , 2017, Molecular and Cellular Biochemistry.

[38]  Yunlong Liu,et al.  Novel Serine 176 Phosphorylation of YBX1 Activates NF-κB in Colon Cancer* , 2017, The Journal of Biological Chemistry.

[39]  J. Geng,et al.  High expression of KIF14 is associated with poor prognosis in patients with epithelial ovarian cancer. , 2017, European review for medical and pharmacological sciences.

[40]  Ya Cao,et al.  Tumor-Associated Neutrophils Recruit Macrophages and T-Regulatory Cells to Promote Progression of Hepatocellular Carcinoma and Resistance to Sorafenib. , 2016, Gastroenterology.

[41]  Yanhua Shi,et al.  Up-regulation of KIF14 is a predictor of poor survival and a novel prognostic biomarker of chemoresistance to paclitaxel treatment in cervical cancer , 2016, Bioscience reports.

[42]  K. Ross,et al.  Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer , 2014, Nature.

[43]  L. Lum,et al.  KIF14 promotes AKT phosphorylation and contributes to chemoresistance in triple-negative breast cancer. , 2014, Neoplasia.

[44]  Maura O'Neil,et al.  Hepatocyte nuclear factor 4 alpha deletion promotes diethylnitrosamine‐induced hepatocellular carcinoma in rodents , 2013, Hepatology.

[45]  Jianhua Yang,et al.  NF-κB and STAT3 signaling pathways collaboratively link inflammation to cancer , 2013, Protein & Cell.

[46]  Yihui Fan,et al.  NF-κB and STAT3 signaling pathways collaboratively link inflammation to cancer , 2013, Protein & Cell.

[47]  B. Gallie,et al.  KIF14 negatively regulates Rap1a–Radil signaling during breast cancer progression , 2012, The Journal of cell biology.