Fetal Parvovirus B19 Infection and Meconium Peritonitis

A 33-year-old primigravida at 26 weeks gestation presented with fetal hydrops and fetal anemia following prior parvovirus B19 infection. The fetus required two intrauterine transfusions of packed red cells. At 35 weeks gestation, a cesarean section was performed for obstetric reasons. As a consequence of a prenatal bowel perforation, the neonate developed meconium peritonitis, for which she needed laparotomy. This case demonstrates that there may be an association between intrauterine parvovirus infection and meconium peritonitis, the latter possibly caused by vascular injury in fetal life.

[1]  S. Chern,et al.  Cutis marmorata telangiectatica congenita associated with an elevated maternal serum human chorionic gonadotrophin level and transitory isolated fetal ascites , 1997, The British journal of dermatology.

[2]  A. Bocking,et al.  NONIMMUNE HYDROPS FETALIS, PULMONARY SEQUESTRATION, AND FAVORABLE NEONATAL OUTCOME , 1996, Obstetrics and gynecology.

[3]  P. Oszukowski,et al.  [Prenatal echocardiography of aortic stenosis]. , 1996, Pediatria polska.

[4]  Salisbury Aj,et al.  Prenatal stroke associated with maternal parvovirus infection. , 1996 .

[5]  J. Kuller,et al.  An association between fetal parvovirus B19 infection and fetal anomalies: a report of two cases. , 1996, American journal of perinatology.

[6]  M. Pike,et al.  Prenatal stroke associated with maternal parvovirus infection. , 1996, Developmental medicine and child neurology.

[7]  S. Odent,et al.  Fetal ascites and oligohydramnios: Prenatal diagnosis of a sialic acid storage disease (index case) , 1995, Prenatal diagnosis.

[8]  M. Pillai,et al.  Management of fetal hydrops associated with parvovirus B19 infection , 1994, British journal of obstetrics and gynaecology.

[9]  B. Benacerraf,et al.  The causes and natural history of fetal ascites , 1994, Prenatal diagnosis.

[10]  E. Gelfand,et al.  Chronic parvovirus B19 infection and systemic necrotising vasculitis: opportunistic infection or aetiological agent? , 1994, The Lancet.

[11]  D. Oepkes,et al.  A fetus with a parvovirus B19 infection and congenital anomalies , 1994, Prenatal diagnosis.

[12]  R. Filly,et al.  Congenital high airway obstruction syndrome (CHAOS): a potential for perinatal intervention. , 1994, Journal of pediatric surgery.

[13]  L. Kreel,et al.  Bowel obstruction. , 1993, Postgraduate medical journal.

[14]  D. Gibellini,et al.  Symptomatic parvovirus B19 infection of one fetus in a twin pregnancy. , 1993, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[15]  R. Goelz,et al.  Perinatal case report of unexpected thalassemia Hb Bart. , 1993, Fetal Diagnosis and Therapy.

[16]  G. Jorch,et al.  Aktuelle Perzentilenkurven für Körpergewicht, Körperlänge und Kopfumfang von Neugeborenem ab 25 SSW , 1993 .

[17]  M. O’Shea,et al.  Long-term outcome in fetal hydrops from parvovirus B19 infection. , 1992, American journal of obstetrics and gynecology.

[18]  K. Fleming,et al.  Clinical and histopathological features of parvovirus B19 infection in the human fetus , 1992, British journal of obstetrics and gynaecology.

[19]  R. Faix,et al.  SPONTANEOUS RESOLUTION OF NONIMMUNE HYDROPS FETALIS SECONDARY TO HUMAN PARVOVIRUS B19 INFECTION , 1992, Obstetrics and gynecology.

[20]  F. Forestier Principales normes biologiques chez le fœtus , 1991 .

[21]  A. Knisely,et al.  Hepatic disease associated with intrauterine parvovirus B19 infection in a newborn premature infant. , 1989, Journal of pediatric gastroenterology and nutrition.

[22]  S. Naides,et al.  Antenatal diagnosis and palliative treatment of non‐immune hydrops fetalis secondary to fetal parvovirus B19 infection , 1989, Prenatal diagnosis.

[23]  T. Schwarz,et al.  HUMAN PARVOVIRUS B19 INFECTION IN PREGNANCY , 1988, The Lancet.

[24]  H. Maeda,et al.  NONIMMUNOLOGIC HYDROPS FETALIS RESULTING FROM INTRAUTERINE HUMAN PARVOVIRUS B‐19 INFECTION: REPORT OF TWO CASES , 1988, Obstetrics and gynecology.

[25]  K. Fleming,et al.  B19 PARVOVIRUS INFECTION OF MYOCARDIAL CELLS , 1988, The Lancet.

[26]  R. Romero Prenatal diagnosis of congenital anomalies , 1988 .

[27]  G. Fleuren,et al.  PARVOVIRUS B19 ASSOCIATED WITH FETAL ABNORMALITY , 1987, The Lancet.

[28]  J. Clewley,et al.  Human parvovirus infection in pregnancy and hydrops fetalis. , 1987, The New England journal of medicine.

[29]  M. Anderson,et al.  Serologically proved intrauterine infection with parvovirus. , 1984, British medical journal.

[30]  S. Guglielmino,et al.  H-1 and X14 parvovirus antibodies in women with abortions or still-births. , 1978, Acta virologica.