A case study of adaptive nonlinear regulation of fed-batch biological reactors

Fed-batch biological reactors are good candidates for the application of adaptive nonlinear techniques because they involve kinetic parameters that are highly uncertain and slowly time-varying. In this paper, the issue is illustrated and discussed with the aid of an industrial application: the ethanol regulation in yeast production processes.

[1]  H G Crabtree,et al.  Observations on the carbohydrate metabolism of tumours. , 1929, The Biochemical journal.

[2]  R. M. Dekkers,et al.  ADAPTIVE CONTROL OF A FED-BATCH BAKER'S YEAST FERMENTATION , 1986 .

[3]  Henry Y. Wang,et al.  Computer‐aided baker's yeast fermentations , 1977, Biotechnology and bioengineering.

[4]  H. B. Verbruggen,et al.  Multiloop Controlled Fed-batch Fermentation Process Using a Selftuning Controller , 1985 .

[5]  Suteaki Shioya,et al.  An advanced micro-computer coupled control system in a baker's yeast fed-batch culture using a tubing method , 1983 .

[6]  Hassan K. Khalil,et al.  Singular perturbation methods in control : analysis and design , 1986 .

[7]  D Williams,et al.  On‐line adaptive control of a fed‐batch fermentation of Saccharomyces cerevisiae , 1986, Biotechnology and bioengineering.

[8]  L. Chen,et al.  Adaptive nonlinear regulation of fed-batch biological reactors: an industrial application , 1991, [1991] Proceedings of the 30th IEEE Conference on Decision and Control.

[9]  ETHANOL-AND RQ-BASED COMPUTER CONTROL IN FED BATCH CULTURE OF BAKER'S YEAST , 1981 .

[10]  S Shioya,et al.  Optimal quality control of bakers' yeast fed‐batch culture using population dynamics , 1982, Biotechnology and bioengineering.

[11]  W. Woehrer,et al.  Regulatory aspects of bakers' yeast metabolism in aerobic fed‐batch cultures , 1981 .

[12]  D. Dochain,et al.  On-Line Estimation and Adaptive Control of Bioreactors , 2013 .

[13]  S Nagai,et al.  Fed batch culture of Saccharomyces cerevisiae: A perspective of computer control to enhance the productivity in baker's yeast cultivation , 1976, Biotechnology and bioengineering.

[14]  G. Bastin,et al.  Adaptive Stabilization of Nonlinear-systems , 1991 .

[15]  A. Johnson,et al.  The control of fed-batch fermentation processes - A survey , 1987, Autom..

[16]  T. Takamatsu,et al.  Optimal control of a semibatch fermentation , 1976, Biotechnology and bioengineering.

[17]  Marie-Noëlle Pons,et al.  Influence of acetate on growth kinetics and production control of Saccharomyces cerevisiae on glucose and ethanol , 1986, Applied Microbiology and Biotechnology.

[18]  Jan Peter Axelsson,et al.  Modelling and Control of Fermentation Processes , 1989 .

[19]  Per Hagander,et al.  Substrate Control of Biotechnical Fedbatch Processes. Robustness and the Role of Adaptivity , 1990 .

[20]  P Peringer,et al.  Modeling and optimal control of bakers yeast production in repeated fed batch culture , 1980 .

[21]  Karl Johan Åström,et al.  Adaptive Control , 1989, Embedded Digital Control with Microcontrollers.

[22]  B Sonnleitner,et al.  Growth of Saccharomyces cerevisiae is controlled by its limited respiratory capacity: Formulation and verification of a hypothesis , 1986, Biotechnology and bioengineering.

[23]  M Kanda,et al.  Profile control scheme in a Bakers' yeast fed‐batch culture , 1985, Biotechnology and bioengineering.

[24]  S. J. Parulekar,et al.  Optimal Control of Fed-Batch Bioreactors , 1985, 1985 American Control Conference.

[25]  Mlb Marc Keulers,et al.  Identification and control of a fed-batch process : application to culture of Saccharomyces cerevisiae , 1993 .

[26]  D. Williams,et al.  Multivariable adaptive control of baker's yeast fermentation , 1986 .

[27]  D. Williams,et al.  Online adaptive control of a fermentation process , 1984 .

[28]  A. Isidori,et al.  Adaptive control of linearizable systems , 1989 .

[29]  B. Pasik-Duncan,et al.  Adaptive Control , 1996, IEEE Control Systems.

[30]  Y. Pomerleau,et al.  Industrial Application of Adaptive Nonlinear Control for Bakers' Yeast Production , 1992 .

[31]  C L Cooney,et al.  Computer‐aided material balancing for prediction of fermentation parameters , 1977, Biotechnology and bioengineering.

[32]  K C Chen,et al.  On‐line optimal control for fed‐batch culture of baker's yeast production , 1985, Biotechnology and bioengineering.

[33]  David G. Taylor,et al.  Adaptive Regulation of Nonlinear Systems with Unmodeled Dynamics , 1988, 1988 American Control Conference.

[34]  Jan Peter Axelsson On the Role of Adaptive Controllers in Fed-Batch Yeast Production , 1988 .

[35]  H C Lim,et al.  Feedback optimization of fed‐batch fermentation , 1987, Biotechnology and bioengineering.