Muscle Wasting and Impaired Myogenesis in Tumor Bearing Mice Are Prevented by ERK Inhibition
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[1] P. Costelli,et al. Glutamine prevents myostatin hyperexpression and protein hypercatabolism induced in C2C12 myotubes by tumor necrosis factor-α , 2011, Amino Acids.
[2] M. Muscaritoli,et al. Muscle atrophy in experimental cancer cachexia: Is the IGF‐1 signaling pathway involved? , 2010, International journal of cancer.
[3] W. Mitch,et al. Satellite cell dysfunction and impaired IGF-1 signaling cause CKD-induced muscle atrophy. , 2010, Journal of the American Society of Nephrology : JASN.
[4] A. Seifalian,et al. Pretreatment with insulin-like growth factor I protects skeletal muscle cells against oxidative damage via PI3K/Akt and ERK1/2 MAPK pathways , 2010, Laboratory Investigation.
[5] Per Aagaard,et al. Molecular aging and rejuvenation of human muscle stem cells , 2009, EMBO molecular medicine.
[6] S. Cook,et al. Myostatin inhibits IGF-I-induced myotube hypertrophy through Akt. , 2009, American journal of physiology. Cell physiology.
[7] P. Costelli,et al. Deacetylase inhibitors modulate the myostatin/follistatin axis without improving cachexia in tumor-bearing mice. , 2009, Current cancer drug targets.
[8] S. Hatakeyama,et al. Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size. , 2009, American journal of physiology. Cell physiology.
[9] S. Ramamoorthy,et al. Decreased Jun-D and myogenin expression in muscle wasting of human cachexia. , 2009, American journal of physiology. Endocrinology and metabolism.
[10] A. Aziz,et al. Cardiotrophin-1 Maintains the Undifferentiated State in Skeletal Myoblasts* , 2009, The Journal of Biological Chemistry.
[11] O. Halevy,et al. Beta-hydroxy-beta-methylbutyrate (HMB) stimulates myogenic cell proliferation, differentiation and survival via the MAPK/ERK and PI3K/Akt pathways. , 2009, Biochimica et biophysica acta.
[12] D. Gerrard,et al. Mitogen-activated protein kinase signaling is necessary for the maintenance of skeletal muscle mass. , 2009, American journal of physiology. Cell physiology.
[13] G. Schuler,et al. Impact of exercise training on myostatin expression in the myocardium and skeletal muscle in a chronic heart failure model , 2009, European journal of heart failure.
[14] Robert B. White,et al. Integrated Functions of Pax3 and Pax7 in the Regulation of Proliferation, Cell Size and Myogenic Differentiation , 2009, PloS one.
[15] Dalia I. Hemdan,et al. Polyphenols prevent clinorotation-induced expression of atrogenes in mouse C2C12 skeletal myotubes. , 2009, The journal of medical investigation : JMI.
[16] D. Kohtz,et al. Fiber-types of sarcomeric proteins expressed in cultured myogenic cells are modulated by the dose of myogenin activity. , 2009, Cellular signalling.
[17] D. Gerrard,et al. Modulation of skeletal muscle fiber type by mitogen‐activated protein kinase signaling , 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[18] M. Muscaritoli,et al. Muscle myostatin signalling is enhanced in experimental cancer cachexia , 2008, European journal of clinical investigation.
[19] A. Pristerá,et al. Tumor Necrosis Factor‐α Inhibition of Skeletal Muscle Regeneration Is Mediated by a Caspase‐Dependent Stem Cell Response , 2008, Stem cells.
[20] F. Padula,et al. Skeletal muscle is enriched in hematopoietic stem cells and not inflammatory cells in cachectic mice , 2008, Neurological research.
[21] P. Tien,et al. Myostatin antisense RNA-mediated muscle growth in normal and cancer cachexia mice , 2008, Gene Therapy.
[22] Nicholas Ling,et al. Myostatin signals through Pax7 to regulate satellite cell self-renewal. , 2008, Experimental cell research.
[23] A. Goldberg,et al. FoxO3 controls autophagy in skeletal muscle in vivo. , 2007, Cell metabolism.
[24] Wei Chen,et al. Differential regulation and properties of MAPKs , 2007, Oncogene.
[25] D. Gerrard,et al. Extracellular signal-regulated kinase pathway is differentially involved in beta-agonist-induced hypertrophy in slow and fast muscles. , 2007, American journal of physiology. Cell physiology.
[26] C. Scuoppo,et al. Conditional Activation of MET in Differentiated Skeletal Muscle Induces Atrophy* , 2007, Journal of Biological Chemistry.
[27] Swarnali Acharyya,et al. Cancer Cachexia Signaling Pathways Continue to Emerge Yet Much Still Points to the Proteasome , 2007, Clinical Cancer Research.
[28] A. Keren,et al. The p38 MAPK signaling pathway: A major regulator of skeletal muscle development , 2006, Molecular and Cellular Endocrinology.
[29] Yan Chen,et al. Extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase pathway is involved in myostatin-regulated differentiation repression. , 2006, Cancer research.
[30] E. Barreiro,et al. The AP‐1/CJUN signaling cascade is involved in muscle differentiation: Implications in muscle wasting during cancer cachexia , 2006, FEBS letters.
[31] M. Molinaro,et al. Tumor necrosis factor‐α gene transfer induces cachexia and inhibits muscle regeneration , 2005 .
[32] Swarnali Acharyya,et al. Dystrophin glycoprotein complex dysfunction: a regulatory link between muscular dystrophy and cancer cachexia. , 2005, Cancer cell.
[33] D. Glass,et al. Skeletal muscle hypertrophy and atrophy signaling pathways. , 2005, The international journal of biochemistry & cell biology.
[34] M. Muscaritoli,et al. Skeletal muscle wasting in tumor-bearing rats is associated with MyoD down-regulation. , 2005, International journal of oncology.
[35] D. Sassoon,et al. Embryonic deregulation of muscle stress signaling pathways leads to altered postnatal stem cell behavior and a failure in postnatal muscle growth. , 2005, Developmental biology.
[36] D. Mann,et al. TNF‐α acts via p38 MAPK to stimulate expression of the ubiquitin ligase atrogin1/MAFbx in skeletal muscle , 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[37] M. Molinaro,et al. Tumor necrosis factor-alpha gene transfer induces cachexia and inhibits muscle regeneration. , 2005, Genesis.
[38] G. Pavlath,et al. Skeletal muscle atrophy leads to loss and dysfunction of muscle precursor cells. , 2004, American journal of physiology. Cell physiology.
[39] B. Olwin,et al. Pax-7 up-regulation inhibits myogenesis and cell cycle progression in satellite cells: a potential mechanism for self-renewal. , 2004, Developmental biology.
[40] O. Halevy,et al. Pattern of Pax7 expression during myogenesis in the posthatch chicken establishes a model for satellite cell differentiation and renewal , 2004, Developmental dynamics : an official publication of the American Association of Anatomists.
[41] A. Goldberg,et al. Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression , 2004, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[42] F. Haddad,et al. Inhibition of MAP/ERK kinase prevents IGF-I-induced hypertrophy in rat muscles. , 2004, Journal of applied physiology.
[43] M. Muscaritoli,et al. Increased Muscle Proteasome Activity Correlates With Disease Severity in Gastric Cancer Patients , 2003, Annals of surgery.
[44] Ashok Kumar,et al. Distinct Signaling Pathways Are Activated in Response to Mechanical Stress Applied Axially and Transversely to Skeletal Muscle Fibers* , 2002, The Journal of Biological Chemistry.
[45] Kanefusa Kato,et al. Innervation‐dependent phosphorylation and accumulation of αB–crystallin and Hsp27 as insoluble complexes in disused muscle , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[46] W. Mitch,et al. Ubiquitin (UbC) Expression in Muscle Cells Is Increased by Glucocorticoids through a Mechanism Involving Sp1 and MEK1* , 2002, The Journal of Biological Chemistry.
[47] P. Hasselgren,et al. Molecular regulation of muscle cachexia: it may be more than the proteasome. , 2002, Biochemical and biophysical research communications.
[48] C. Y. Wang,et al. NF-kappaB-induced loss of MyoD messenger RNA: possible role in muscle decay and cachexia. , 2000, Science.
[49] Jiahuai Han,et al. Induction of terminal differentiation by constitutive activation of p38 MAP kinase in human rhabdomyosarcoma cells. , 2000, Genes & development.
[50] T. Lømo,et al. Ras is involved in nerve-activity-dependent regulation of muscle genes , 2000, Nature Cell Biology.
[51] D J Glass,et al. Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt. , 1999, Science.
[52] J. Florini,et al. Raf-1 activation stimulates proliferation and inhibits IGF-stimulated differentiation in L6A1 myoblasts. , 1999, Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
[53] E. Duda,et al. TNF inhibits myogenesis and downregulates the expression of myogenic regulatory factors myoD and myogenin. , 1997, European journal of cell biology.
[54] J. Florini,et al. The Mitogenic and Myogenic Actions of Insulin-like Growth Factors Utilize Distinct Signaling Pathways* , 1997, The Journal of Biological Chemistry.
[55] G. Strassmann,et al. Evidence for the involvement of interleukin 6 in experimental cancer cachexia. , 1992, The Journal of clinical investigation.