Evaluation of the Utility of the Fournier's Gangrene Severity Index in the Management of Fournier's Gangrene in North India: A Multicentre Retrospective Study

Objective: To study the utility of Fournier's Gangrene Severity Index (FGSI) with mortality predictive value in our tertiary institutes in North India. Materials and Methods: A retrospective study of 95 cases of Fournier's Gangrene (FG), admitted from 2009 to 2011, was carried out. We analysed clinical and laboratory findings, various prognostic factors, surgical treatments and their outcomes in FG patients. FGSI was used as individual variable to estimate the severity of FG; the effects of these factors on mortality were also evaluated. Results: The overall mean age was 46.5 ± 15.6 (range 24-82) years. Anorectal and urological regions were the main sites of the infection. The most common site of infection origin was scrotum in 81.3% in group A and 41.2% in group B. One or more predisposing factors such as diabetes mellitus (DM; 55%) malignancies (4.6%), chronic renal failure (4.5%) and previous surgery (9.2%) were detected. We observed mortality in 26.5% cases (17/65). The FGSI calculated averaged 5.95 ± 365 in group A and 9.44 ± 2.56 in group B, at the time of admission (P > 0.05). Conclusion: In FG, an early diagnosis and early surgical debridement are essential. The FGSI seems to be an excellent tool for the outcome prediction.

[1]  L. Guerra,et al.  Fournier's gangrene: our experience in 5 years, bibliographic review and assessment of the Fournier's gangrene severity index. , 2009, Archivos espanoles de urologia.

[2]  H. Unalp,et al.  Fournier's gangrene: evaluation of 68 patients and analysis of prognostic variables. , 2008, Journal of postgraduate medicine.

[3]  A. Ersay,et al.  FACTORS AFFECTING MORTALITY OF FOURNIER’S GANGRENE: REVIEW OF 70 PATIENTS , 2007, ANZ journal of surgery.

[4]  A. Tuncel,et al.  Fournier's gangrene: Three years of experience with 20 patients and validity of the Fournier's Gangrene Severity Index Score. , 2006, European urology.

[5]  A. Chiu,et al.  Is Fournier’s Gangrene Severity Index Useful for Predicting Outcome of Fournier’s Gangrene? , 2005, Urologia Internationalis.

[6]  M. Arslan,et al.  Fournier's gangrene: experience with 25 patients and use of Fournier's gangrene severity index score. , 2004, Urology.

[7]  R. Kirby,et al.  Improving outcomes in Fournier's gangrene , 2004, BJU international.

[8]  Ç. Çal,et al.  Outcome Analysis in Patients With Fournier’s Gangrene: Report of 45 Cases , 2003 .

[9]  G. Zibari,et al.  Management of Fournier's Gangrene: An Eleven Year Retrospective Analysis of Early Recognition, Diagnosis, and Treatment , 2002, The American surgeon.

[10]  N. Eke,et al.  Fournier's gangrene: a review of 1726 cases , 2000, The British journal of surgery.

[11]  J. L. Nogueira March,et al.  [Fournier's gangrene: anatomo-clinical features in adults and children. Therapy update]. , 2000, Actas Urológicas Españolas.

[12]  Moody,et al.  Fournier’s gangrene in a modern surgical setting: improved survival with aggressive management , 1999, BJU international.

[13]  J. Mouiel,et al.  Gangrene of the perineum. , 1996, Urology.

[14]  R. Bihrle,et al.  Genital Fournier's gangrene: experience with 38 patients. , 1996, Urology.

[15]  M. Walter,et al.  [Fournier's gangrene]. , 1996, Annales de chirurgie.

[16]  L. Palmer,et al.  Outcome prediction in patients with Fournier's gangrene. , 1995, The Journal of urology.

[17]  R. Pearl,et al.  Causes, presentation and survival of fifty-seven patients with necrotizing fasciitis of the male genitalia. , 1990, Surgery, gynecology & obstetrics.

[18]  M. Resnick,et al.  Fournier's gangrene: report of 20 patients. , 1984, The Journal of urology.

[19]  J. Miller The importance of early diagnosis and surgical treatment of necrotizing fasciitis. , 1983, Surgery, gynecology & obstetrics.