论文信息 - Letter to the Editor – Comments on published article by F. Deisenhammer et al.

Letter to the Editor – Comments on published article by F. Deisenhammer et al.

We completely miss mention about structural proteins of CNS. Detection of 14-3-3 protein in CSF is a part of diagnostic criteria of Creutzfeldt–Jakob disease [2]. The Neuron Specific Enolase (NSE) and Tau protein have probably the same diagnostic relevance [3,4]. Also the diagnostic role of so-called CSF triplet of Tau protein, phospho-Tau and beta-amyloid has been established in the diagnostics of Alzheimer dementia [5].

P. Adam | O. Sobek | J. Svatoňová

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[3] H. Homburger,et al. Quantitation of 14-3-3 and neuron-specific enolase proteins in CSF in Creutzfeldt–Jakob disease , 2001, Neurology.

[4] D. Lanska. Diagnosis of Creutzfeldt–Jakob disease: Effect of clinical criteria on incidence estimates Analysis of EEG and CSF 14-3-3 proteins as aids to the diagnosis of Creutzfeldt–Jakob disease , 2001, Neurology.

[5] J. M. Polo. [Diagnosis of Creutzfeldt-Jakob disease]. , 1998, Neurologia.

[6] M. Spiegel-Adolf,et al. Cerebrospinal fluid. , 1965, Progress in neurology and psychiatry.

[7] H. Merritt,et al. The cerebrospinal fluid , 1935 .