Discovery of 3H-imidazo[4,5-c]quinolin-4(5H)-ones as potent and selective dipeptidyl peptidase IV (DPP-4) inhibitors: use of a carboxylate prodrug to improve bioavailability.
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E. Sugaru | Tomonori Kobayashi | H. Kimura | Jun Tadano | Katsuya Uchiyama | N. Sawada | Yohei Ikuma | H. Hochigai | Noriko Nunami | T. Umezome | Yasumitsu Sakurai | M. Ono | Yuko Hirose | H. Nakahira