Comparison analysis of illicit cocaine samples.

A rapid method for comparison analysis of illicit cocaine samples has been developed. The raw data are obtained by capillary gas chromatography using a nitrogen-phosphorus detector. The area ratios of four alkaloids (tropacocaine, norcocaine, cis-cinnamoylcocaine, and trans-cinnamoylcocaine) to cocaine are calculated for each sample. These ratios are compiled in a computer database which allows easy comparison of samples and makes possible reliable conclusions regarding their commonality of origin.

[1]  R. Cooks,et al.  Mass-analyzed ion kinetic energy (MIKE) spectrometry and the direct analysis of coca. , 1981, Journal of Ethnopharmacology.

[2]  K. E. Janzen.  Cross-Matching of Cocaine Samples. A Case Study , 1987 .

[3]  Arthur J. L. Cooper,et al.  Analysis of manufacturing by-products and impurities in illicit cocaine via high-performance liquid chromatography and photodiode array detection. , 1987, Journal of chromatography.

[4]  M. Novotny,et al.  Analysis of marijuana samples from different origins by high-resolution gas-liquid chromatography for forensic application. , 1976, Analytical chemistry.

[5]  H. Huizer.  Analytical studies on illicit heroin. II. Comparison of samples. , 1983, Journal of forensic sciences.

[6]  M. Lebelle,et al.  The examination of illicit cocaine. , 1988, Journal of forensic sciences.

[7]  T. Lukaszewski,et al.  Impurities and Artifacts of Illicit Cocaine , 1980 .

[8]  L. Rivier.  Analysis of alkaloids in leaves of cultivated Erythroxylum and characterization of alkaline substances used during coca chewing. , 1981, Journal of ethnopharmacology.

[9]  C. Y. Ma,et al.  Constituents of Erythroxylon coca. II. Gas-chromatographic analysis of cocaine and other alkaloids in coca leaves. , 1981, Journal of ethnopharmacology.

[10]  C. W. Therrien,et al.  Decision, Estimation and Classification: An Introduction to Pattern Recognition and Related Topics , 1989 .

[11]  Arthur J. L. Cooper,et al.  Capillary gas chromatographic-electron capture detection of coca-leaf-related impurities in illicit cocaine: 2,4-diphenylcyclobutane-1,3-dicarboxylic acids, 1,4-diphenylcyclobutane-2,3-dicarboxylic acids and their alkaloidal precursors, the truxillines. , 1987, Journal of chromatography.

[12]  B. Kratochvil,et al.  Sampling Errors in the Determination of Cocaine in Seized Drugs , 1984 .

[13]  M. Elsohly,et al.  Chromatographic and spectroscopic profiles of Cannabis of different origins: Part I. , 1988, Journal of forensic sciences.

[14]  L. Strömberg.  Comparative gas chromatographic analysis of narcotics. II. Amphetamine sulphate. , 1975, Journal of chromatography.

[15]  Auf der Heyde,et al.  Analyzing Chemical Data in More than Two Dimensions. A Tutorial on Factor and Cluster Analysis. , 1990 .

[16]  J. Liu.  Approaches to Drug Sample Differentiation. I: A Conceptual Review , 1981 .

[17]  Andrew C. Allen,et al.  Determination of manufacturing impurities in heroin by capillary gas chromatography with electron capture detection after derivatization with heptafluorobutyric anhydride , 1984 .