Sutureless sealing of penetrating corneal wounds using a laser‐activated thin film adhesive

To demonstrate the feasibility of a novel, thin film, laser‐activated adhesive in sealing penetrative corneal wounds with a view to replacing sutures in ophthalmic operations.

[1]  C. Kucukerdonmez,et al.  Fibrin glue versus sutures for conjunctival autografting in pterygium surgery: a prospective comparative study , 2008, British Journal of Ophthalmology.

[2]  R R Alfano,et al.  NIR laser tissue welding of in vitro porcine cornea and sclera tissue , 2004, Lasers in surgery and medicine.

[3]  M. R. Jackson,et al.  Fibrin sealants in surgical practice: An overview. , 2001, American journal of surgery.

[4]  M. Refojo,et al.  Sealing choroidal perforations with cyanoacrylate adhesives. , 1970, Archives of ophthalmology.

[5]  S. Kaufman,et al.  Human fibrin tissue adhesive for sutureless lamellar keratoplasty and scleral patch adhesion: a pilot study. , 2003, Ophthalmology.

[6]  M A Mainster,et al.  Ophthalmic applications of infrared lasers -- thermal considerations. , 1979, Investigative ophthalmology & visual science.

[7]  H. Boisjoly,et al.  Advances in the use of adhesives in ophthalmology , 2004, Current opinion in ophthalmology.

[8]  Michael F. Land,et al.  The Human Eye: Structure and Function , 1999, Nature Medicine.

[9]  A Katzir,et al.  Temperature-controlled CO2 laser tissue welding of ocular tissues. , 1997, Survey of ophthalmology.

[10]  I. Avni,et al.  Biological Glue in Pterygium Surgery With a Rotational Flap or Sliding Flaps , 2008, Cornea.

[11]  Zdravko Mandić,et al.  [Lasers in ophthalmology]. , 2006, Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti.

[12]  M. Grinstaff,et al.  Ophthalmic adhesives: a materials chemistry perspective , 2008 .

[13]  T. Hida,et al.  Retinal toxicity of cyanoacrylate tissue adhesive in the rabbit. , 1988, Retina.

[14]  L. Poole-Warren,et al.  Chitosan adhesive for laser tissue repair: In vitro characterization , 2005, Lasers in surgery and medicine.

[15]  T. Desmettre,et al.  Diode laser‐induced thermal damage evaluation on the retina with a liposome dye system , 1999, Lasers in Surgery and Medicine.

[16]  Terry Kim,et al.  Tissue adhesives in corneal cataract incisions , 2007, Current opinion in ophthalmology.

[17]  Michael R Hamblin,et al.  Healing of perforating rat corneal incisions closed with photodynamic laser‐activated tissue glue , 2004, Lasers in surgery and medicine.

[18]  D. Sampson,et al.  In vitro and in vivo tissue repair with laser‐activated chitosan adhesive , 2007, Lasers in surgery and medicine.

[19]  I. Bleiweiss,et al.  The significance of malignancies incidental to microcalcifications in breast spot localization biopsy specimens. , 2001, American journal of surgery.

[20]  Irradiation of rabbit retina with diode and Nd:YAG lasers. , 1995, The British journal of ophthalmology.

[21]  Carmen A. Puliafito,et al.  Lasers in ophthalmology , 1981, Bulletins et memoires de la Societe francaise d'ophtalmologie.

[22]  Antonio Lauto,et al.  Sutureless nerve repair with laser-activated chitosan adhesive: a pilot in vivo study. , 2008, Photomedicine and laser surgery.

[23]  U Ziese,et al.  Corneal collagen fibril structure in three dimensions: Structural insights into fibril assembly, mechanical properties, and tissue organization , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[24]  D. Hardten,et al.  Fibrin glue for the prevention of epithelial ingrowth after laser in situ keratomileusis. , 2003, Journal of cataract and refractive surgery.

[25]  D. Wakefield,et al.  Chitosan-vancomysin composite biomaterial as a laser activated surgical adhesive with regional antimicrobial activity. , 2010, Biomacromolecules.

[26]  Eric Tremblay,et al.  Robotic laser tissue welding of sclera using chitosan films , 2009, Lasers in surgery and medicine.

[27]  W J Stark,et al.  Corneal perforations. Changing methods of treatment, 1960--1980. , 1982, Ophthalmology.

[28]  Y Ikada,et al.  In vitro and in vivo degradation of films of chitin and its deacetylated derivatives. , 1997, Biomaterials.

[29]  Siegal Je,et al.  Surgical removal of cyanoacrylate adhesive after accidental instillation in the anterior chamber. , 1989 .

[30]  D. Mawad,et al.  Adhesive biomaterials for tissue reconstruction , 2008 .