Suppression of inhibitor of differentiation 2, a target of mutant p53, is required for gain-of-function mutations.
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Gang Liu | Ariane Scoumanne | Wensheng Yan | Xinbin Chen | Gang Liu | Wensheng Yan | Xinbin Chen | A. Scoumanne
[1] A. Iavarone,et al. Id2 Mediates Tumor Initiation, Proliferation, and Angiogenesis in Rb Mutant Mice , 2005, Molecular and Cellular Biology.
[2] P. Chène,et al. The gain of function of the p53 mutant Asp281Gly is dependent on its ability to form tetramers. , 2002, Cancer letters.
[3] Y. Itahana,et al. Role of Id-2 in the maintenance of a differentiated and noninvasive phenotype in breast cancer cells. , 2003, Cancer research.
[4] T. Jacks,et al. Mutant p53 Gain of Function in Two Mouse Models of Li-Fraumeni Syndrome , 2004, Cell.
[5] K. Kinzler,et al. Disruption of p53 in human cancer cells alters the responses to therapeutic agents. , 1999, The Journal of clinical investigation.
[6] M. Cummings,et al. Expression profiling correlates with treatment response in women with advanced serous epithelial ovarian cancer , 2006, International journal of cancer.
[7] Giulia Piaggio,et al. Gain of function of mutant p53: the mutant p53/NF-Y protein complex reveals an aberrant transcriptional mechanism of cell cycle regulation. , 2006, Cancer cell.
[8] Wensheng Yan,et al. Targeted repression of bone morphogenetic protein 7, a novel target of the p53 family, triggers proliferative defect in p53-deficient breast cancer cells. , 2007, Cancer research.
[9] C. Prives,et al. Mutant p53 gain of function: the NF-Y connection. , 2006, Cancer Cell.
[10] Xinbin Chen,et al. The Activation Domains, the Proline-rich Domain, and the C-terminal Basic Domain in p53 Are Necessary for Acetylation of Histones on the Proximal p21 Promoter and Interaction with p300/CREB-binding Protein* , 2003, The Journal of Biological Chemistry.
[11] A. Iavarone,et al. Id2 Drives Differentiation and Suppresses Tumor Formation in the Intestinal Epithelium , 2004, Cancer Research.
[12] V. Rotter,et al. Mutant p53 enhances nuclear factor kappaB activation by tumor necrosis factor alpha in cancer cells. , 2007, Cancer research.
[13] J. Cleveland,et al. Activation of c-myc Gene Expression by Tumor-Derived p53 Mutants Requires a Discrete C-Terminal Domain , 1998, Molecular and Cellular Biology.
[14] G. Zambetti,et al. The p53 mutation “gradient effect” and its clinical implications , 2007, Journal of cellular physiology.
[15] R. Bernards,et al. A System for Stable Expression of Short Interfering RNAs in Mammalian Cells , 2002, Science.
[16] A. Iavarone,et al. The protein ENH is a cytoplasmic sequestration factor for Id2 in normal and tumor cells from the nervous system. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[17] F. Kittrell,et al. Ataxia telangiectasia-mutated and p53 are potential mediators of chloroquine-induced resistance to mammary carcinogenesis. , 2007, Cancer research.
[18] N. Sarvetnick,et al. BMP4 Regulates Pancreatic Progenitor Cell Expansion through Id2* , 2006, Journal of Biological Chemistry.
[19] M. Scian,et al. Tumor-Derived p53 Mutants Induce NF-κB2 Gene Expression , 2005, Molecular and Cellular Biology.
[20] W. Deppert,et al. Mutant p53R270H gain of function phenotype in a mouse model for oncogene‐induced mammary carcinogenesis , 2007, International journal of cancer.
[21] L. Strong,et al. Gain of Function of a p53 Hot Spot Mutation in a Mouse Model of Li-Fraumeni Syndrome , 2004, Cell.
[22] R. Alani,et al. Id proteins in cell growth and tumorigenesis. , 2003, Cancer cell.
[23] M. Christmann,et al. Differential sensitivity of malignant glioma cells to methylating and chloroethylating anticancer drugs: p53 determines the switch by regulating xpc, ddb2, and DNA double-strand breaks. , 2007, Cancer research.
[24] X. Chen,et al. p53, through p21 (WAF1/CIP1), induces cyclin D1 synthesis. , 1995, Cancer research.
[25] J. Manola,et al. TP53 mutations and survival in squamous-cell carcinoma of the head and neck. , 2007, The New England journal of medicine.
[26] A. Iavarone,et al. E Proteins and Id2 Converge on p57Kip2 To Regulate Cell Cycle in Neural Cells , 2006, Molecular and Cellular Biology.
[27] Xinbin Chen,et al. Identification of a Novel p53 Functional Domain That Is Necessary for Mediating Apoptosis* , 1998, The Journal of Biological Chemistry.
[28] G. Blandino,et al. Mutant p53 gain of function: reduction of tumor malignancy of human cancer cell lines through abrogation of mutant p53 expression , 2006, Oncogene.
[29] G. Landberg,et al. High ID2 protein expression correlates with a favourable prognosis in patients with primary breast cancer and reduces cellular invasiveness of breast cancer cells , 2005, International journal of cancer.
[30] Xinbin Chen,et al. p21B, a variant of p21Waf1/Cip1, is induced by the p53 family , 2002, Oncogene.
[31] Jean-Philippe Coppé,et al. Id proteins in epithelial cells. , 2003, Experimental cell research.
[32] Justis P. Ehlers,et al. Functional gene expression analysis uncovers phenotypic switch in aggressive uveal melanomas. , 2006, Cancer research.