Enhancement of anti-tumor activity in melanoma using arginine deiminase fused with 30Kc19α protein

[1]  T. Park,et al.  Enhanced efficiency of generating human-induced pluripotent stem cells using Lin28-30Kc19 fusion protein , 2022, Frontiers in Bioengineering and Biotechnology.

[2]  N. Sun,et al.  Argininosuccinate synthase 1, arginine deprivation therapy and cancer management , 2022, Frontiers in pharmacology.

[3]  Nathaniel S. Hwang,et al.  Cellular direct conversion by cell penetrable OCT4-30Kc19 protein and BMP4 growth factor , 2022, Biomaterials Research.

[4]  Thanh Loc Nguyen,et al.  Nanozyme-Based Enhanced Cancer Immunotherapy , 2022, Tissue Engineering and Regenerative Medicine.

[5]  P. Gulati,et al.  Microbial arginine deiminase: A multifaceted green catalyst in biomedical sciences. , 2021, International journal of biological macromolecules.

[6]  T. Park,et al.  Enhancement of Wound Healing Efficacy by Increasing the Stability and Skin-Penetrating Property of bFGF Using 30Kc19α-Based Fusion Protein. , 2021, Advanced biology.

[7]  Nathaniel S. Hwang,et al.  Intracellular Delivery of Recombinant RUNX2 Facilitated by Cell-Penetrating Protein for the Osteogenic Differentiation of hMSCs. , 2020, ACS biomaterials science & engineering.

[8]  J. Trent,et al.  Arginine Depletion Therapy with ADI-PEG20 Limits Tumor Growth in Argininosuccinate Synthase–Deficient Ovarian Cancer, Including Small-Cell Carcinoma of the Ovary, Hypercalcemic Type , 2020, Clinical Cancer Research.

[9]  Nathaniel S. Hwang,et al.  Protein-based direct reprogramming of fibroblasts to neuronal cells using 30Kc19 protein and transcription factor Ascl1. , 2020, The international journal of biochemistry & cell biology.

[10]  P. Gulati,et al.  Microbial enzymes for deprivation of amino acid metabolism in malignant cells: biological strategy for cancer treatment , 2020, Applied Microbiology and Biotechnology.

[11]  Sutapa Barua,et al.  Current technologies to endotoxin detection and removal for biopharmaceutical purification , 2019, Biotechnology and bioengineering.

[12]  B. Sitohy,et al.  Aspergillus nidulans thermostable arginine deiminase-Dextran conjugates with enhanced molecular stability, proteolytic resistance, pharmacokinetic properties and anticancer activity. , 2019, Enzyme and microbial technology.

[13]  Muhammad Imran,et al.  PEGylation: a promising strategy to overcome challenges to cancer-targeted nanomedicines: a review of challenges to clinical transition and promising resolution , 2019, Drug Delivery and Translational Research.

[14]  T. Crook,et al.  A Phase I Study of Pegylated Arginine Deiminase (Pegargiminase), Cisplatin, and Pemetrexed in Argininosuccinate Synthetase 1-Deficient Recurrent High-grade Glioma , 2019, Clinical Cancer Research.

[15]  B. Kreikemeyer,et al.  Arginine-Depleting Enzymes – An Increasingly Recognized Treatment Strategy for Therapy-Refractory Malignancies , 2018, Cellular Physiology and Biochemistry.

[16]  Ying Tu,et al.  MMP-Responsive 'Smart' Drug Delivery and Tumor Targeting. , 2018, Trends in pharmacological sciences.

[17]  T. Park,et al.  Enzyme delivery using protein-stabilizing and cell-penetrating 30Kc19α protein nanoparticles , 2017 .

[18]  C. Overall,et al.  New intracellular activities of matrix metalloproteinases shine in the moonlight. , 2017, Biochimica et biophysica acta. Molecular cell research.

[19]  Yoko Hirata,et al.  Application of a novel HiBiT peptide tag for monitoring ATF4 protein expression in Neuro2a cells , 2017, Biochemistry and biophysics reports.

[20]  Han Choe,et al.  Soluble expression and purification of bioactive interleukin 33 in E. coli , 2017, Biotechnology and Bioprocess Engineering.

[21]  D. Fukumura,et al.  Arginine dependence of tumor cells: targeting a chink in cancer’s armor , 2016, Oncogene.

[22]  T. Park,et al.  Protein‐stabilizing and cell‐penetrating properties of α‐helix domain of 30Kc19 protein , 2016, Biotechnology journal.

[23]  R. Dey,et al.  PEGylation in anti-cancer therapy: An overview , 2016 .

[24]  Yun-Ru Chen,et al.  Selective Intracellular Delivery of Recombinant Arginine Deiminase (ADI) Using pH-Sensitive Cell Penetrating Peptides To Overcome ADI Resistance in Hypoxic Breast Cancer Cells. , 2016, Molecular pharmaceutics.

[25]  T. Park,et al.  Soluble expression and stability enhancement of transcription factors using 30Kc19 cell-penetrating protein , 2015, Applied Microbiology and Biotechnology.

[26]  K. Han,et al.  Escherichia coli EDA is a novel fusion expression partner to improve solubility of aggregation-prone heterologous proteins. , 2015, Journal of biotechnology.

[27]  Byung-Gee Kim,et al.  Synthetic fusion protein design and applications. , 2015, Biotechnology advances.

[28]  T. Park,et al.  Dimerization of 30Kc19 protein in the presence of amphiphilic moiety and importance of Cys-57 during cell penetration , 2014, Biotechnology journal.

[29]  T. Park,et al.  Identification and characterization of a novel cell-penetrating peptide of 30Kc19 protein derived from Bombyx mori , 2014 .

[30]  D. S. Lee,et al.  Synthesis of Mycoplasma arginine deiminase in E. coli using stress-responsive proteins. , 2014, Enzyme and microbial technology.

[31]  Frank Y. S. Chuang,et al.  Arginine starvation-associated atypical cellular death involves mitochondrial dysfunction, nuclear DNA leakage, and chromatin autophagy , 2014, Proceedings of the National Academy of Sciences.

[32]  Yu-Chin Chiu,et al.  Intracellular delivery of recombinant arginine deiminase (rADI) by heparin-binding hemagglutinin adhesion peptide restores sensitivity in rADI-resistant cancer cells. , 2014, Molecular pharmaceutics.

[33]  F. Zhang,et al.  Discussion about several potential drawbacks of PEGylated therapeutic proteins. , 2014, Biological & pharmaceutical bulletin.

[34]  Jeong Ah Kim,et al.  Enzyme delivery using the 30Kc19 protein and human serum albumin nanoparticles. , 2014, Biomaterials.

[35]  P. Szlosarek,et al.  Targeting Arginine-Dependent Cancers with Arginine-Degrading Enzymes: Opportunities and Challenges , 2013, Cancer research and treatment : official journal of Korean Cancer Association.

[36]  D. Wheatley,et al.  Improved method for expression and isolation of the Mycoplasma hominis arginine deiminase from the recombinant strain of Escherichia coli. , 2013, Journal of biotechnology.

[37]  M. Wangpaichitr,et al.  Arginine Deiminase Resistance in Melanoma Cells Is Associated with Metabolic Reprogramming, Glucose Dependence, and Glutamine Addiction , 2013, Molecular Cancer Therapeutics.

[38]  Bodil Fadnes,et al.  Tissue- and Cell-Specific Co-localization of Intracellular Gelatinolytic Activity and Matrix Metalloproteinase 2 , 2013, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

[39]  Shin Sik Choi,et al.  A protein delivery system using 30Kc19 cell-penetrating protein originating from silkworm. , 2012, Biomaterials.

[40]  Shin Sik Choi,et al.  Stabilization of enzymes by the recombinant 30Kc19 protein , 2012 .

[41]  Jin-Seung Park,et al.  A novel Escherichia coli solubility enhancer protein for fusion expression of aggregation-prone heterologous proteins. , 2011, Enzyme and microbial technology.

[42]  Cong-Zhao Zhou,et al.  Crystal structure of the 30 K protein from the silkworm Bombyx mori reveals a new member of the β-trefoil superfamily. , 2011, Journal of structural biology.

[43]  M. Metsis,et al.  Cell Penetrating Peptides , 2000 .

[44]  B. Delage,et al.  Arginine deprivation and argininosuccinate synthetase expression in the treatment of cancer , 2010, International journal of cancer.

[45]  N. Savaraj,et al.  Resistance to arginine deiminase treatment in melanoma cells is associated with induced argininosuccinate synthetase expression involving c-Myc/HIF-1α/Sp4 , 2009, Molecular Cancer Therapeutics.

[46]  T. Park,et al.  Expression of Bombyx mori 30Kc19 protein in Escherichia coli and its anti-apoptotic effect in Sf9 cell , 2009 .

[47]  M. Rath,et al.  Patterns of MMP-2 and MMP-9 expression in human cancer cell lines. , 2009, Oncology reports.

[48]  Frank Y. S. Chuang,et al.  Arginine deiminase as a novel therapy for prostate cancer induces autophagy and caspase-independent apoptosis. , 2009, Cancer research.

[49]  Y. Ni,et al.  Arginine deiminase, a potential anti-tumor drug. , 2008, Cancer letters.

[50]  Ű. Langel,et al.  Cell-penetrating peptides as vectors for peptide, protein and oligonucleotide delivery. , 2006, Current opinion in pharmacology.

[51]  Shin Sik Choi,et al.  Beneficial effect of silkworm hemolymph on a CHO cell system: Inhibition of apoptosis and increase of EPO production. , 2005, Biotechnology and bioengineering.

[52]  M. Idoate,et al.  Expression and serum levels of MMP‐2 and MMP‐9 during human melanoma progression , 2005, Clinical and experimental dermatology.

[53]  T. Park,et al.  Enhanced production of recombinant protein inEscherichia coli using silkworm hemolymph , 2005 .

[54]  S. Singh,et al.  Solubilization and refolding of bacterial inclusion body proteins. , 2005, Journal of bioscience and bioengineering.

[55]  Ana Maria Mendes Pereira,et al.  Invasion-associated MMP-2 and MMP-9 are Up-regulated Intracellularly in Concert with Apoptosis Linked to Melanoma Cell Detachment , 2005, Clinical & Experimental Metastasis.

[56]  Eun Jeong Kim,et al.  Inhibition of Apoptosis by a Bombyx mori Gene , 2008, Biotechnology progress.

[57]  S. Curley,et al.  Incidence and distribution of argininosuccinate synthetase deficiency in human cancers , 2004, Cancer.

[58]  A. Lavoinne,et al.  Argininosuccinate synthetase from the urea cycle to the citrulline-NO cycle. , 2003, European journal of biochemistry.

[59]  Eun Jeong Kim,et al.  Anti-apoptosis engineering , 2003 .

[60]  F. González-Candelas,et al.  Evolution of arginine deiminase (ADI) pathway genes. , 2002, Molecular phylogenetics and evolution.

[61]  J. Bomalaski,et al.  Pegylated arginine deiminase (ADI-SS PEG20,000 mw) inhibits human melanomas and hepatocellular carcinomas in vitro and in vivo. , 2002, Cancer research.

[62]  T. Park,et al.  Kinetic Effect of Silkworm Hemolymph on the Delayed Host Cell Death in an Insect Cell‐Baculovirus System , 1999, Biotechnology progress.

[63]  R D Appel,et al.  Protein identification and analysis tools in the ExPASy server. , 1999, Methods in molecular biology.

[64]  K. Miyazaki,et al.  Potent growth inhibition of human tumor cells in culture by arginine deiminase purified from a culture medium of a Mycoplasma-infected cell line. , 1990, Cancer research.

[65]  E. Oginsky [92] Isolation and determination of arginine and citrulline , 1957 .