A CONVENIENT FERRIC CHLORIDE CATALYZED SYNTHESIS OF 5-ALKOXYCARBONYL-4-ARYL-3,4-DIHYDROPYRIMIDIN-2(1H)-ONES UNDER MICROWAVE IRRADIATION

ABSTRACT A series of ethyl 4-aryl-6-methyl-1,2,3,4-tetrahydropyrimidin-2-one-5-carboxylates 4 were synthesized by the condensation of aromatic aldehydes, ethyl acetoacetate and urea in the presence of ferric chloride hexahydrate under microwave irradiation. The reactions were completed in 4–6 min with 87–92% yield.

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