Induction of CTGF by TGF-beta1 in normal and radiation enteritis human smooth muscle cells: Smad/Rho balance and therapeutic perspectives.

[1]  C. Stournaras,et al.  LIM-kinase 2 and Cofilin Phosphorylation Mediate Actin Cytoskeleton Reorganization Induced by Transforming Growth Factor-β* , 2005, Journal of Biological Chemistry.

[2]  J. Bourhis,et al.  An unusual cause of upper gastrointestinal haemorrhage , 2005, Gut.

[3]  M. Spiteri,et al.  Connective tissue growth factor expression and induction by transforming growth factor-beta is abrogated by simvastatin via a Rho signaling mechanism. , 2004, American journal of physiology. Lung cellular and molecular physiology.

[4]  J. Lefaix,et al.  The radiation-induced fibroatrophic process: therapeutic perspective via the antioxidant pathway. , 2004, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[5]  B. Fenton,et al.  Effect of Administration of Lovastatin on the Development of Late Pulmonary Effects after Whole-Lung Irradiation in a Murine Model , 2004, Radiation research.

[6]  J. Bourhis,et al.  Gene Expression Profile in Human Late Radiation Enteritis Obtained by High-Density cDNA Array Hybridization , 2004, Radiation research.

[7]  J. Overgaard,et al.  Prediction of normal tissue radiosensitivity from polymorphisms in candidate genes. , 2003, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[8]  M. Hauer-Jensen,et al.  Bowel injury: current and evolving management strategies. , 2003, Seminars in radiation oncology.

[9]  U. Malmqvist,et al.  Stretch-induced contractile differentiation of vascular smooth muscle: sensitivity to actin polymerization inhibitors. , 2003, American journal of physiology. Cell physiology.

[10]  C. Haie-meder,et al.  Fibrogenic signals in patients with radiation enteritis are associated with increased connective tissue growth factor expression. , 2003, International journal of radiation oncology, biology, physics.

[11]  D. Abraham,et al.  Prostacyclin derivatives prevent the fibrotic response to TGFβ2 by inhibiting the Ras/MEK/ERK pathway , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[12]  R. Goldschmeding,et al.  Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy? , 2002, Matrix biology : journal of the International Society for Matrix Biology.

[13]  S. Sa,et al.  CTGF expression in mesangial cells: involvement of SMADs, MAP kinase, and PKC. , 2002, Kidney international.

[14]  E. Robertis,et al.  Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-β , 2002, Nature Cell Biology.

[15]  D. Shegogue,et al.  Role of p38 MAPK in transforming growth factor beta stimulation of collagen production by scleroderma and healthy dermal fibroblasts. , 2002, The Journal of investigative dermatology.

[16]  S. Sebti,et al.  Signaling events required for transforming growth factor-beta stimulation of connective tissue growth factor expression by cultured human lung fibroblasts. , 2001, Archives of biochemistry and biophysics.

[17]  M. Goppelt‐Struebe,et al.  Rho‐dependent inhibition of the induction of connective tissue growth factor (CTGF) by HMG CoA reductase inhibitors (statins) , 2001, British journal of pharmacology.

[18]  S. Sa,et al.  CTGF and SMADs, Maintenance of Scleroderma Phenotype Is Independent of SMAD Signaling* , 2001, The Journal of Biological Chemistry.

[19]  M. Goppelt‐Struebe,et al.  Induction of Connective Tissue Growth Factor by Activation of Heptahelical Receptors , 2000, The Journal of Biological Chemistry.

[20]  J. Massagué,et al.  TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders , 2000, Cell.

[21]  H. Moses,et al.  Interdependent SMAD and JNK Signaling in Transforming Growth Factor-β-mediated Transcription* , 1999, The Journal of Biological Chemistry.

[22]  T. Yamakawa,et al.  Mechanotransduction of rat aortic vascular smooth muscle cells requires RhoA and intact actin filaments. , 1999, Circulation research.

[23]  C. Phiel,et al.  Identification of distinct molecular phenotypes in cultured gastrointestinal smooth muscle cells. , 1998, Gastroenterology.

[24]  Gary R. Grotendorst,et al.  A novel transforming growth factor beta response element controls the expression of the connective tissue growth factor gene. , 1996, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[25]  M. Graham Pathogenesis of Intestinal Strictures in Crohn's Disease—An Update , 1995, Inflammatory bowel diseases.

[26]  M. Sporn,et al.  Transforming growth factor type beta: rapid induction of fibrosis and angiogenesis in vivo and stimulation of collagen formation in vitro. , 1986, Proceedings of the National Academy of Sciences of the United States of America.

[27]  Chul-woo Yang,et al.  Pravastatin treatment attenuates interstitial inflammation and fibrosis in a rat model of chronic cyclosporine-induced nephropathy. , 2004, American journal of physiology. Renal physiology.

[28]  A. Nicholson,et al.  Regulation of TGF-β1-induced connective tissue growth factor expression in airway smooth muscle cells , 2004 .