Effect of radiation therapy on facial nerve cable autografts

Facial nerve cable autografts were performed on 20 cats with 10 animals receiving 6,000 Rads of postoperative irradiation over six weeks. Testing by clinical appearance, pontograms, and axon counts showed no statistical difference in the operated only and the operated plus irradiated groups. Pontograms illustrated the clinical observance of spasticity, delay and weakness often seen after grafting. This animal work tends to verify the clinical impression that in patients requiring postoperative irradiation for a malignancy necessitating excision and grafting of the facial nerve, anticipated results should be equivalent to the facial nerve cable autografts without postoperative irradiation.

[1]  J. Conley,et al.  Prognosis of malignant tumors of the parotid gland with facial paralysis. , 1975, Archives of otolaryngology.

[2]  Van Coevorden Sj,et al.  Benign tumors of the parotid gland. , 1973 .

[3]  M. V. Van Allen,et al.  Reflex response of the orbicularis oculi muscle to supraorbital nerve stimulation: study in normal subjects and in peripheral facial paresis. , 1969, Transactions of the American Neurological Association.

[4]  R. Baker,et al.  Carcinoma of the parotid gland. , 1966, Archives of surgery.

[5]  G. Fletcher,et al.  PLACE AND TECHNICS OF RADIATION THERAPY IN THE MANAGEMENT OF MALIGNANT TUMORS OF THE MAJOR SALIVARY GLANDS. , 1965, Radiology.

[6]  L. Guth,et al.  AN ELECTROPHYSIOLOGICAL STUDY OF THE EARLY STAGES OF PERIPHERAL NERVE REGENERATION. , 1965, Experimental neurology.

[7]  F. Lathrop.  LVII Management of the Facial Nerve during Operations on the Parotid Gland , 1963, The Annals of otology, rhinology, and laryngology.

[8]  F. Lathrop.  Benign tumors of the parotid gland: A twenty‐five year review , 1962, The Laryngoscope.

[9]  J. Conley.  Facial nerve grafting. , 1961, Archives of otolaryngology.

[10]  M. Karlan,et al.  Spontaneous regeneration of the seventh nerve. , 1960, Archives of surgery.

[11]  H. Martin,et al.  Spontaneous Return of Function Following Surgical Section or Excision of the Seventh Cranial Nerve in the Surgery of Parotid Tumors , 1957, Annals of surgery.

[12]  J. Conley.  Facial rehabilitation following radical parotid-gland surgery. , 1957, A.M.A. archives of otolaryngology.

[13]  H. Grundfest,et al.  THE ELECTRICAL ACTIVITY OF REGENERATING NERVES IN THE CAT , 1944 .

[14]  S. Bunnell.  SURGICAL REPAIR OF THE FACIAL NERVE , 1937 .

[15]  A. B. Duel,et al.  THE OPERATIVE TREATMENT OF FACIAL PALSY: BY THE INTRODUCTION OF NERVE GRAFTS INTO THE FALLOPIAN CANAL AND BY OTHER INTRATEMPORAL METHODS , 1932 .