论文信息 - Persistent B‐cell Lymphopenia, Multiorgan Disease, and Erythema Multiforme Caused by Mycoplasma pneumoniae Infection

Persistent B‐cell Lymphopenia, Multiorgan Disease, and Erythema Multiforme Caused by Mycoplasma pneumoniae Infection

Abstract: We report a 6‐year‐old girl in whom Mycoplasma pneumoniae infection presenting with erythema multiforme, multiorgan, and hematologic dysfunctions induced a long‐standing, marked B‐cell lymphopenia. An increase of CD8+ lymphocytes was also detected. We suggest that a selective cytotoxic T lymphocyte‐dependent B cell lysis and the expansion of super‐antigen activated CD8+ T cells may account for the multiorgan and hematologic disturbances triggered by M. pneumoniae.

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