Frequent PVT1 rearrangement and novel chimeric genes PVT1-NBEA and PVT1-WWOX occur in multiple myeloma with 8q24 abnormality.
暂无分享,去创建一个
I. Hanamura | T. Taki | M. Taniwaki | S. Horiike | J. Kuroda | K. Okuda | T. Otsuki | Y. Tsutsumi | M. Nitta | Yosuke Matsumoto | K. Nishida | Tsutomu Kobayashi | H. Nagoshi | Natsumi Sakamoto | S. Kobayashi | Mio Yamamoto‐Sugitani | Hisao Nagoshi
[1] Y. Akao,et al. Bcl-2 is a better therapeutic target than c-Myc, but attacking both could be a more effective treatment strategy for B-cell lymphoma with concurrent Bcl-2 and c-Myc overexpression. , 2011, Experimental hematology.
[2] I. Hanamura,et al. Establishment and Characterization of a Novel Human Myeloma Cell Line, AMU-MM1, From a Multiple Myeloma Patient Involving Central Nerve System After Treatment with Bortezomib , 2010 .
[3] B. Barlogie,et al. International Myeloma Working Group molecular classification of multiple myeloma: spotlight review , 2009, Leukemia.
[4] N. Cross,et al. Loss of 1p and rearrangement of MYC are associated with progression of smouldering myeloma to myeloma: sequential analysis of a single case , 2009, Haematologica.
[5] J. Carpten,et al. Identification of copy number abnormalities and inactivating mutations in two negative regulators of nuclear factor-kappaB signaling pathways in Waldenstrom's macroglobulinemia. , 2009, Cancer research.
[6] R. Vij,et al. Neurobeachin (NBEA) is a target of recurrent interstitial deletions at 13q13 in patients with MGUS and multiple myeloma. , 2009, Experimental hematology.
[7] R. Siebert,et al. Identification of candidate tumour suppressor gene loci for Hodgkin and Reed‐Sternberg cells by characterisation of homozygous deletions in classical Hodgkin lymphoma cell lines , 2008, British journal of haematology.
[8] P. L. Bergsagel,et al. Characterization of MYC translocations in multiple myeloma cell lines. , 2008, Journal of the National Cancer Institute. Monographs.
[9] Y. Hayashi,et al. Identification of the novel AML1 fusion partner gene, LAF4, a fusion partner of MLL, in childhood T-cell acute lymphoblastic leukemia with t(2;21)(q11;q22) by bubble PCR method for cDNA , 2008, Oncogene.
[10] R. Stephens,et al. The Identification of MicroRNAs in a Genomically Unstable Region of Human Chromosome 8q24 , 2008, Molecular Cancer Research.
[11] K. Mimori,et al. Clinical significance of the reduced expression of G protein gamma 7 (GNG7) in oesophageal cancer , 2008, British Journal of Cancer.
[12] A. Al-Katib,et al. Chromosome aberrations in a series of 120 multiple myeloma cases with abnormal karyotypes , 2007, American journal of hematology.
[13] Letizia Carramusa,et al. The PVT‐1 oncogene is a Myc protein target that is overexpressed in transformed cells , 2007, Journal of cellular physiology.
[14] Wen-Lin Kuo,et al. Amplification of PVT1 Contributes to the Pathophysiology of Ovarian and Breast Cancer , 2007, Clinical Cancer Research.
[15] L. Bruhn,et al. Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma. , 2007, Cancer cell.
[16] L. Staudt,et al. Frequent engagement of the classical and alternative NF-kappaB pathways by diverse genetic abnormalities in multiple myeloma. , 2007, Cancer cell.
[17] David R Williams,et al. Gene-expression signature of benign monoclonal gammopathy evident in multiple myeloma is linked to good prognosis. , 2006, Blood.
[18] Yongsheng Huang,et al. Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transplantation. , 2006, Blood.
[19] R. Siebert,et al. Identification of recurrent chromosomal breakpoints in multiple myeloma with complex karyotypes by combined G-banding, spectral karyotyping, and fluorescence in situ hybridization analyses. , 2006, Cancer genetics and cytogenetics.
[20] Shigeru Chiba,et al. A robust algorithm for copy number detection using high-density oligonucleotide single nucleotide polymorphism genotyping arrays. , 2005, Cancer research.
[21] Y. Pekarsky,et al. Functional association between Wwox tumor suppressor protein and p73, a p53 homolog. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[22] H. Aburatani,et al. An opposing view on WWOX protein function as a tumor suppressor. , 2003, Cancer research.
[23] M. Rocchi,et al. Heterogeneous pattern of chromosomal breakpoints involving the MYC locus in multiple myeloma , 2003, Genes, chromosomes & cancer.
[24] R. Bataille,et al. Rearrangements of the c-myc oncogene are present in 15% of primary human multiple myeloma tumors. , 2001, Blood.
[25] R. Bataille,et al. Cytogenetic, interphase, and multicolor fluorescence in situ hybridization analyses in primary plasma cell leukemia: a study of 40 patients at diagnosis, on behalf of the Intergroupe Francophone du Myélome and the Groupe Français de Cytogénétique Hématologique. , 2001, Blood.
[26] B. Barlogie,et al. Multicolour spectral karyotyping identifies new translocations and a recurring pathway for chromosome loss in multiple myeloma , 2001, British journal of haematology.
[27] Friedrich W. Herberg,et al. Neurobeachin: A Protein Kinase A-Anchoring,beige/Chediak-Higashi Protein Homolog Implicated in Neuronal Membrane Traffic , 2000, The Journal of Neuroscience.
[28] A. Bednarek,et al. WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer. , 2000, Cancer research.
[29] P. L. Bergsagel,et al. Diverse karyotypic abnormalities of the c-myc locus associated with c-myc dysregulation and tumor progression in multiple myeloma. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[30] N. Kakazu,et al. Combined spectral karyotyping and DAPI banding analysis of chromosome abnormalities in myelodysplastic syndrome , 1999, Genes, chromosomes & cancer.
[31] E. Macintyre,et al. Simultaneous detection of MYC, BVR1, and PVT1 translocations in lymphoid malignancies by fluorescence in situ hybridization , 1998, Genes, chromosomes & cancer.
[32] S. Kitano,et al. Identification and Cloning of Human G-Protein γ 7, Down-regulated in Pancreatic Cancer , 1998 .
[33] M. Taniwaki,et al. The Ig heavy chain gene is frequently involved in chromosomal translocations in multiple myeloma and plasma cell leukemia as detected by in situ hybridization. , 1997, Blood.
[34] M. Taniwaki,et al. Translocations and amplification of the BCL2 gene are detected in interphase nuclei of non-Hodgkin's lymphoma by in situ hybridization with yeast artificial chromosome clones. , 1995, Blood.
[35] B. Barlogie,et al. Cytogenetic findings in 200 patients with multiple myeloma. , 1995, Cancer genetics and cytogenetics.
[36] K. Huppi,et al. Chimeric transcripts with an open reading frame are generated as a result of translocation to the Pvt‐1 region in mouse B‐cell tumors , 1994, International journal of cancer.
[37] A. Palumbo,et al. Human homologue of Moloney leukemia virus integration-4 locus (MLVI-4), located 20 kilobases 3' of the myc gene, is rearranged in multiple myelomas. , 1990, Cancer research.
[38] R. Benner,et al. Amplification of the c-myc and the pvt-like region in human multiple myeloma. , 1990, Oncogene.
[39] I. Magrath,et al. Localization of breakpoints by polymerase chain reactions in burkitt's lymphoma with 8;14 translocations , 1990 .
[40] J. Bishop,et al. Effects of translocations on transcription from PVT , 1990, Molecular and cellular biology.
[41] J. Bishop,et al. The PVT gene frequently amplifies with MYC in tumor cells , 1989, Molecular and cellular biology.
[42] B. Barlogie,et al. Plasma Cell Karyotype in Multiple Myeloma , 1988 .
[43] E. Rassart,et al. Proviral integration site Mis-1 in rat thymomas corresponds to the pvt-1 translocation breakpoint in murine plasmacytomas , 1986, Molecular and Cellular Biology.
[44] P. Bevan,et al. Analysis of G banded karyotypes in myeloma cells. , 1986, Journal of clinical pathology.
[45] Wei Huang,et al. Frequent epigenetic inactivation of the receptor tyrosine kinase EphA5 by promoter methylation in human breast cancer. , 2010, Human pathology.
[46] M. Schwab,et al. The neurobeachin gene spans the common fragile site FRA13A , 2005, Human Genetics.
[47] G. Klein,et al. Amplification of c-myc and pvt-1 homologous sequences in acute nonlymphatic leukemia. , 1988, Leukemia research.