Body surface Laplacian mapping: modeling and clinical application

The purpose of this investigation was to elucidate effects of torso volume conduction on the body surface Laplacian map (BSLM) compared with the body surface potential map (BSPM) by computer modeling, and to test the applicability of body surface Laplacian mapping to the clinical diagnosis of abnormalities in cardiac electrical activity. Volume conductor effects on simulated BSLMs and BSPMs were compared using a spherical conductor model. BSLMs and BSPMs were obtained and studied experimentally in eight patients with cardiac abnormalities, including left bundle branch block (LBBB), premature ventricular depolarizations, (PVDs), and right ventricular (RV) pacemaker. The modeling and experimental studies demonstrate that torso volume conduction has much less smoothing effect on the BSLM than on the BSPM. Preliminary clinical study demonstrates that BSLMs can resolve and image regional myocardial events and can detect abnormal cardiac conduction patterns with high spatial resolution.<<ETX>>

[1]  R. Cohen,et al.  Body surface Laplacian ECG mapping , 1992, IEEE Transactions on Biomedical Engineering.

[2]  J. .. Abildskov,et al.  Experimental Evidence for Regional Cardiac Influence in Body Surface Isopotential Maps of Dogs , 1976, Circulation research.

[3]  B. Taccardi,et al.  Current and Potential Fields Generated by Two Dipoles , 1970, Circulation research.

[4]  Bin He,et al.  Body Surface Laplacian Mapping In Man , 1991, Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society Volume 13: 1991.

[5]  R C Barr,et al.  Experimental Basis for QRS and T Wave Potentials in the WPW Syndrome: The Relation of Epicardial to Body Surface Potential Distributions in the Intact Chimpanzee , 1978, Circulation research.

[6]  R. Cohen,et al.  A 3-D finite element cardiac model and its application to body surface Laplacian mapping , 1992, Proceedings Computers in Cardiology.

[7]  R E Ideker,et al.  Eccentric dipole in a spherical medium: generalized expression for surface potentials. , 1973, IEEE transactions on bio-medical engineering.

[8]  R. Plonsey,et al.  The Effects of Variations in Conductivity and Geometrical Parameters on the Electrocardiogram, Using an Eccentric Spheres Model , 1979, Circulation research.

[9]  R J Cohen,et al.  Body surface Laplacian mapping of cardiac electrical activity. , 1992, The American journal of cardiology.

[10]  R. Ideker,et al.  Values and limitations of surface isopotential mapping techniques in the detection and localization of multiple discrete epicardial events. , 1977, Journal of electrocardiology.