Serum plakophilin‐3 autoreactivity in paraneoplastic pemphigus

Summary Background  Paraneoplastic pemphigus (PNP) is a malignancy‐associated autoimmune disease in which circulating autoantibodies recognize various polypeptides that constitute the desmosomes and hemidesmosomes of epithelial structures.

[1]  D. Zillikens,et al.  Development of ELISA for the specific determination of autoantibodies against envoplakin and periplakin in paraneoplastic pemphigus. , 2009, Clinica chimica acta; international journal of clinical chemistry.

[2]  R. Müllegger,et al.  Autoantibodies against desmocollins in European patients with pemphigus , 2009, Clinical and experimental dermatology.

[3]  Xue-jun Zhu,et al.  Detection of anti-envoplakin and anti-periplakin autoantibodies by ELISA in patients with paraneoplastic pemphigus , 2009, Archives of Dermatological Research.

[4]  H. Mouquet,et al.  Detection and characterization of anti-envoplakin linker autoantibodies in paraneoplastic pemphigus using specific bead-based assay. , 2008, Clinical immunology.

[5]  F. van Roy,et al.  Plakophilin-3-deficient mice develop hair coat abnormalities and are prone to cutaneous inflammation. , 2008, The Journal of investigative dermatology.

[6]  K. Green,et al.  Desmosomes: new perspectives on a classic. , 2007, The Journal of investigative dermatology.

[7]  C. V. van Noesel,et al.  Acquired palmoplantar keratoderma and immunobullous disease associated with antibodies to desmocollin 3 , 2007, The British journal of dermatology.

[8]  F. van Roy,et al.  Defining desmosomal plakophilin-3 interactions , 2003, The Journal of cell biology.

[9]  M. Pittelkow,et al.  Classification, clinical manifestations, and immunopathological mechanisms of the epithelial variant of paraneoplastic autoimmune multiorgan syndrome: a reappraisal of paraneoplastic pemphigus. , 2001, Archives of dermatology.

[10]  H. Fujiwara,et al.  Immunoblotting detection of γ‐catenin (plakoglobin) antibody in the serum of a patient with paraneoplastic pemphigus , 2001, The British journal of dermatology.

[11]  P. Kools,et al.  Plakophilin-3, a novel armadillo-like protein present in nuclei and desmosomes of epithelial cells. , 1999, Journal of cell science.

[12]  T. Nishikawa,et al.  Antibodies against desmoglein 3 (pemphigus vulgaris antigen) are present in sera from patients with paraneoplastic pemphigus and cause acantholysis in vivo in neonatal mice. , 1998, The Journal of clinical investigation.

[13]  F. Watt,et al.  Envoplakin and periplakin are components of the paraneoplastic pemphigus antigen complex. , 1998, The Journal of investigative dermatology.

[14]  M. Amagai,et al.  Characterization of paraneoplastic pemphigus autoantigens by immunoblot analysis. , 1994, The Journal of investigative dermatology.

[15]  S. Kim,et al.  Paraneoplastic pemphigus. An autoimmune mucocutaneous disease associated with neoplasia , 1991, The New England journal of medicine.