Past, present and future of Focused Ultrasound as an adjunct or complement to DIPG/DMG therapy: A consensus of the 2021 FUSF DIPG meeting

[1]  Lauren M Sanders,et al.  Author Correction: Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome , 2022, Nature Cancer.

[2]  G. Storm,et al.  Imaged-guided focused ultrasound in combination with various formulations of doxorubicin for the treatment of diffuse intrinsic pontine glioma , 2022, Translational Medicine Communications.

[3]  Lauren M Sanders,et al.  Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome , 2022, Nature Cancer.

[4]  S. LeBlang,et al.  Focused ultrasound for the treatment of glioblastoma , 2022, Journal of Neuro-Oncology.

[5]  K. Hynynen,et al.  MR-guided focused ultrasound enhances delivery of trastuzumab to Her2-positive brain metastases , 2021, Science Translational Medicine.

[6]  V. Ferrera,et al.  Safety evaluation of a clinical focused ultrasound system for neuronavigation guided blood-brain barrier opening in non-human primates , 2021, Scientific Reports.

[7]  J. Sheehan,et al.  Sonodynamic therapy for gliomas , 2021, Journal of Neuro-Oncology.

[8]  M. Bugiani,et al.  The neurovascular unit in diffuse intrinsic pontine gliomas. , 2021, Free neuropathology.

[9]  F. Di Meco,et al.  Intracranial Sonodynamic Therapy With 5-Aminolevulinic Acid and Sodium Fluorescein: Safety Study in a Porcine Model , 2021, Frontiers in Oncology.

[10]  P. Canoll,et al.  Focused ultrasound mediated blood–brain barrier opening is safe and feasible in a murine pontine glioma model , 2021, Scientific Reports.

[11]  J. Kuo,et al.  Neuronavigation-guided focused ultrasound for transcranial blood-brain barrier opening and immunostimulation in brain tumors , 2021, Science Advances.

[12]  J. Rubin,et al.  Focused Ultrasound-Enhanced Delivery of Intranasally Administered Anti-Programmed Cell Death-Ligand 1 Antibody to an Intracranial Murine Glioma Model , 2021, Pharmaceutics.

[13]  P. Canoll,et al.  Focused Ultrasound-Mediated Blood-Brain Barrier Opening Increases Delivery and Efficacy of Etoposide for Glioblastoma Treatment. , 2020, International journal of radiation oncology, biology, physics.

[14]  K. Hynynen,et al.  MRI-guided focused ultrasound enhances drug delivery in experimental diffuse intrinsic pontine glioma. , 2020, Journal of controlled release : official journal of the Controlled Release Society.

[15]  P. Robertson,et al.  Electronic DNA Analysis of CSF Cell-free Tumor DNA to Quantify Multi-gene Molecular Response in Pediatric High-grade Glioma , 2020, Clinical Cancer Research.

[16]  P. Dayton,et al.  Focused Ultrasound for Immunomodulation of the Tumor Microenvironment , 2020, The Journal of Immunology.

[17]  T. Kanda,et al.  Development of a human in vitro blood–brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance , 2020, Fluids and Barriers of the CNS.

[18]  N. McDannold,et al.  Blood-brain barrier disruption and delivery of irinotecan in a rat model using a clinical transcranial MRI-guided focused ultrasound system , 2020, Scientific Reports.

[19]  N. McDannold,et al.  Observed Effects of Whole-Brain Radiation Therapy on Focused Ultrasound Blood-Brain Barrier Disruption. , 2020, Ultrasound in medicine & biology.

[20]  E. Konofagou,et al.  Focused ultrasound induced-blood-brain barrier opening in mouse brain receiving radiosurgery dose of radiation enhances local delivery of systemic therapy. , 2020, The British journal of radiology.

[21]  I. Sardi,et al.  A New Treatment Opportunity for DIPG and Diffuse Midline Gliomas: 5-ALA Augmented Irradiation, the 5aai Regimen , 2020, Brain sciences.

[22]  C. James,et al.  Ultrasound-mediated Delivery of Paclitaxel for Glioma: A Comparative Study of Distribution, Toxicity, and Efficacy of Albumin-bound Versus Cremophor Formulations , 2019, Clinical Cancer Research.

[23]  N. McDannold,et al.  Acoustic feedback enables safe and reliable carboplatin delivery across the blood-brain barrier with a clinical focused ultrasound system and improves survival in a rat glioma model , 2019, Theranostics.

[24]  K. Hynynen,et al.  MR-guided Focused Ultrasound Facilitates Sonodynamic Therapy with 5-Aminolevulinic Acid in a Rat Glioma Model , 2019, Scientific Reports.

[25]  M. Monje,et al.  Diffuse Intrinsic Pontine Glioma: From Diagnosis to Next-Generation Clinical Trials , 2019, Current Treatment Options in Neurology.

[26]  M. Monje,et al.  ALK2 inhibitors display beneficial effects in preclinical models of ACVR1 mutant diffuse intrinsic pontine glioma , 2019, Communications Biology.

[27]  Arthur André,et al.  Safety and Feasibility of Repeated and Transient Blood–Brain Barrier Disruption by Pulsed Ultrasound in Patients with Recurrent Glioblastoma , 2019, Clinical Cancer Research.

[28]  Michael C. Rusch,et al.  H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo , 2019, Acta Neuropathologica.

[29]  M. Weller,et al.  Chemotherapy sensitization of glioblastoma by focused ultrasound‐mediated delivery of therapeutic liposomes , 2019, Journal of controlled release : official journal of the Controlled Release Society.

[30]  K. Hynynen,et al.  Blood-Brain Barrier Opening in Primary Brain Tumors with Non-invasive MR-Guided Focused Ultrasound: A Clinical Safety and Feasibility Study , 2019, Scientific Reports.

[31]  E. Konofagou,et al.  A Clinical System for Non-invasive Blood-Brain Barrier Opening Using a Neuronavigation-Guided Single-Element Focused Ultrasound Transducer. , 2019, Ultrasound in medicine & biology.

[32]  Siping Chen,et al.  Sonodynamic Therapy on Intracranial Glioblastoma Xenografts Using Sinoporphyrin Sodium Delivered by Ultrasound with Microbubbles , 2018, Annals of Biomedical Engineering.

[33]  P. Biswas,et al.  Focused ultrasound combined with microbubble‐mediated intranasal delivery of gold nanoclusters to the brain , 2018, Journal of controlled release : official journal of the Controlled Release Society.

[34]  K. Hynynen,et al.  Brainstem blood brain barrier disruption using focused ultrasound: A demonstration of feasibility and enhanced doxorubicin delivery , 2018, Journal of controlled release : official journal of the Controlled Release Society.

[35]  Mariella G. Filbin,et al.  Non-inflammatory tumor microenvironment of diffuse intrinsic pontine glioma , 2018, Acta neuropathologica communications.

[36]  R. McLendon,et al.  Histone H3.3K27M Represses p16 to Accelerate Gliomagenesis in a Murine Model of DIPG , 2017, Molecular Cancer Research.

[37]  N. McDannold,et al.  Growth inhibition in a brain metastasis model by antibody delivery using focused ultrasound-mediated blood-brain barrier disruption. , 2016, Journal of controlled release : official journal of the Controlled Release Society.

[38]  Richard J Price,et al.  Drug and gene delivery across the blood-brain barrier with focused ultrasound. , 2015, Journal of controlled release : official journal of the Controlled Release Society.

[39]  J. Ptak,et al.  Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord , 2015, Proceedings of the National Academy of Sciences.

[40]  Angelika Alonso,et al.  Ultrasound-induced blood-brain barrier opening for drug delivery. , 2015, Frontiers of neurology and neuroscience.

[41]  T. Santarius,et al.  Predicting the “usefulness” of 5-ALA-derived tumor fluorescence for fluorescence-guided resections in pediatric brain tumors: a European survey , 2014, Acta Neurochirurgica.

[42]  Kullervo Hynynen,et al.  Alzheimer disease in a mouse model: MR imaging-guided focused ultrasound targeted to the hippocampus opens the blood-brain barrier and improves pathologic abnormalities and behavior. , 2014, Radiology.

[43]  W. Stummer,et al.  Kinetics of porphyrin fluorescence accumulation in pediatric brain tumor cells incubated in 5-aminolevulinic acid , 2014, Acta Neurochirurgica.

[44]  Chih-Kuang Yeh,et al.  Combining Microbubbles and Ultrasound for Drug Delivery to Brain Tumors: Current Progress and Overview , 2014, Theranostics.

[45]  R. Kebudi,et al.  Management of Diffuse Pontine Gliomas in Children: Recent Developments , 2013, Pediatric Drugs.

[46]  K. Hynynen,et al.  Focused ultrasound delivers targeted immune cells to metastatic brain tumors. , 2013, Cancer research.

[47]  N. McDannold,et al.  Ultrasound-mediated blood-brain/blood-tumor barrier disruption improves outcomes with trastuzumab in a breast cancer brain metastasis model. , 2012, Journal of controlled release : official journal of the Controlled Release Society.

[48]  Natalia Vykhodtseva,et al.  Improved anti-tumor effect of liposomal doxorubicin after targeted blood-brain barrier disruption by MRI-guided focused ultrasound in rat glioma. , 2012, Ultrasound in medicine & biology.

[49]  Natalia Vykhodtseva,et al.  The kinetics of blood brain barrier permeability and targeted doxorubicin delivery into brain induced by focused ultrasound. , 2012, Journal of controlled release : official journal of the Controlled Release Society.

[50]  W. Tran,et al.  Microbubble and ultrasound radioenhancement of bladder cancer , 2012, British Journal of Cancer.

[51]  Gregory J. Czarnota,et al.  Tumor radiation response enhancement by acoustical stimulation of the vasculature , 2012, Proceedings of the National Academy of Sciences.

[52]  Yoojin Lee,et al.  Photodynamic therapy: current evidence and applications in dermatology. , 2011, Seminars in cutaneous medicine and surgery.

[53]  Kimito Yamada,et al.  Use of 5-aminolevulinic acid for the confirmation of deep-seated brain tumors during stereotactic biopsy. Report of 2 cases. , 2011, Journal of neurosurgery.

[54]  Mu-Yi Hua,et al.  Blood-brain barrier disruption with focused ultrasound enhances delivery of chemotherapeutic drugs for glioblastoma treatment. , 2010, Radiology.

[55]  Natalia Vykhodtseva,et al.  Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI‐guided focused ultrasound , 2007, International journal of cancer.

[56]  I. Langmoen,et al.  Management of pediatric pontine gliomas , 1991, Child's Nervous System.