Transcutaneous Cervical Vagal Nerve Stimulation in Patients with Posttraumatic Stress Disorder (PTSD): A Pilot Study of Effects on PTSD Symptoms and Interleukin-6 Response to Stress

[1]  Amit J. Shah,et al.  Effect of transcutaneous cervical vagus nerve stimulation on the pituitary adenylate cyclase-activating polypeptide (PACAP) response to stress: A randomized, sham controlled, double blind pilot study , 2020, Comprehensive psychoneuroendocrinology.

[2]  Amit J. Shah,et al.  Transcutaneous vagal nerve stimulation blocks stress-induced activation of Interleukin-6 and interferon-γ in posttraumatic stress disorder: A double-blind, randomized, sham-controlled trial , 2020, Brain, behavior, & immunity - health.

[3]  Amit J. Shah,et al.  Digital Cardiovascular Biomarker Responses to Transcutaneous Cervical Vagus Nerve Stimulation: State-Space Modeling, Prediction, and Simulation , 2020, JMIR mHealth and uHealth.

[4]  Amit J Shah,et al.  Application of Noninvasive Vagal Nerve Stimulation to Stress-Related Psychiatric Disorders , 2020, Journal of personalized medicine.

[5]  Amit J. Shah,et al.  Non-invasive vagal nerve stimulation decreases brain activity during trauma scripts , 2020, Brain Stimulation.

[6]  Vitaly Napadow,et al.  Electrical stimulation of cranial nerves in cognition and disease , 2020, Brain Stimulation.

[7]  Amit J. Shah,et al.  Transcutaneous Cervical Vagal Nerve Stimulation Reduces Sympathetic Responses to Stress in Posttraumatic Stress Disorder , 2020 .

[8]  Amit J. Shah,et al.  Automatic Detection of Target Engagement in Transcutaneous Cervical Vagal Nerve Stimulation for Traumatic Stress Triggers , 2020, IEEE Journal of Biomedical and Health Informatics.

[9]  Omer T. Inan,et al.  Quantifying acute physiological biomarkers of transcutaneous cervical vagal nerve stimulation in the context of psychological stress , 2019, Brain Stimulation.

[10]  J. Deuchars,et al.  Effects of transcutaneous vagus nerve stimulation in individuals aged 55 years or above: potential benefits of daily stimulation , 2019, Aging.

[11]  M. Kilgard,et al.  Vagus nerve stimulation reverses the extinction impairments in a model of PTSD with prolonged and repeated trauma , 2019, Stress.

[12]  Charles W. Huang,et al.  Noninvasive vagus nerve stimulation alters neural response and physiological autonomic tone to noxious thermal challenge , 2019, PloS one.

[13]  Alfred B. Yu,et al.  Laboratory Administration of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS): Technique, Targeting, and Considerations. , 2019, Journal of visualized experiments : JoVE.

[14]  O. Levantsevych,et al.  Posttraumatic stress disorder is associated with enhanced interleukin-6 response to mental stress in subjects with a recent myocardial infarction , 2019, Brain, Behavior, and Immunity.

[15]  J. Tarn,et al.  The Effects of Noninvasive Vagus Nerve Stimulation on Fatigue and Immune Responses in Patients With Primary Sjögren's Syndrome , 2018, Neuromodulation : journal of the International Neuromodulation Society.

[16]  M. Bikson,et al.  Transcutaneous auricular vagus nerve stimulation (taVNS) for improving oromotor function in newborns , 2018, Brain Stimulation.

[17]  C. McIntyre,et al.  Vagus nerve stimulation as a tool for enhancing extinction in exposure-based therapies , 2018, Psychopharmacology.

[18]  Mark S. George,et al.  Short trains of transcutaneous auricular vagus nerve stimulation (taVNS) have parameter-specific effects on heart rate , 2018, Brain Stimulation.

[19]  Zengjian Wang,et al.  A distinct biomarker of continuous transcutaneous vagus nerve stimulation treatment in major depressive disorder , 2018, Brain Stimulation.

[20]  Omer T. Inan,et al.  Toward closed-loop transcutaneous vagus nerve stimulation using peripheral cardiovascular physiological biomarkers: A proof-of-concept study , 2018, 2018 IEEE 15th International Conference on Wearable and Implantable Body Sensor Networks (BSN).

[21]  Abhishek Datta,et al.  Limited output transcranial electrical stimulation (LOTES-2017): Engineering principles, regulatory statutes, and industry standards for wellness, over-the-counter, or prescription devices with low risk , 2018, Brain Stimulation.

[22]  Zengjian Wang,et al.  Frequency-dependent functional connectivity of the nucleus accumbens during continuous transcutaneous vagus nerve stimulation in major depressive disorder. , 2017, Journal of psychiatric research.

[23]  Yan V. Sun,et al.  Hemodynamic, catecholamine, vasomotor and vascular responses: Determinants of myocardial ischemia during mental stress. , 2017, International journal of cardiology.

[24]  Su Golder,et al.  Safety of transcranial direct current stimulation: Evidence based update 2016 , 2017, Brain Stimulation.

[25]  John B. Williamson,et al.  Non-invasive Vagal Nerve Stimulation Effects on Hyperarousal and Autonomic State in Patients with Posttraumatic Stress Disorder and History of Mild Traumatic Brain Injury: Preliminary Evidence , 2017, Front. Med..

[26]  J. Bremner,et al.  Vagus Nerve Stimulation: Back to the Future. , 2017, The American journal of psychiatry.

[27]  K. D'ostilio,et al.  Evidence of activation of vagal afferents by non-invasive vagus nerve stimulation: An electrophysiological study in healthy volunteers , 2017, Cephalalgia : an international journal of headache.

[28]  L. Ulloa,et al.  Neuroimmune Interactions in Schizophrenia: Focus on Vagus Nerve Stimulation and Activation of the Alpha-7 Nicotinic Acetylcholine Receptor , 2017, Front. Immunol..

[29]  P. Schnurr,et al.  The Clinician-Administered PTSD Scale for DSM–5 (CAPS-5): Development and Initial Psychometric Evaluation in Military Veterans , 2017, Psychological assessment.

[30]  Shamim Nemati,et al.  Heart rate-based window segmentation improves accuracy of classifying posttraumatic stress disorder using heart rate variability measures , 2017, Physiological measurement.

[31]  H. Møller,et al.  Transcutaneous cervical vagal nerve stimulation modulates cardiac vagal tone and tumor necrosis factor‐alpha , 2017, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[32]  S. Brookes,et al.  Neurogenic and myogenic patterns of electrical activity in isolated intact mouse colon , 2017, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[33]  E. Nam,et al.  Optimization of Transcutaneous Vagus Nerve Stimulation Using Functional MRI , 2017, Neuromodulation : journal of the International Neuromodulation Society.

[34]  Yan V. Sun,et al.  The Mental Stress Ischemia Prognosis Study: Objectives, Study Design, and Prevalence of Inducible Ischemia , 2017, Psychosomatic medicine.

[35]  D. Dougherty,et al.  A 5-Year Observational Study of Patients With Treatment-Resistant Depression Treated With Vagus Nerve Stimulation or Treatment as Usual: Comparison of Response, Remission, and Suicidality. , 2017, The American journal of psychiatry.

[36]  Robert L. Rennaker,et al.  Parametric characterization of neural activity in the locus coeruleus in response to vagus nerve stimulation , 2017, Experimental Neurology.

[37]  Eleni Frangos,et al.  Access to Vagal Projections via Cutaneous Electrical Stimulation of the Neck: fMRI Evidence in Healthy Humans , 2017, Brain Stimulation.

[38]  Jukka Peltola,et al.  Vagus nerve stimulation improves working memory performance , 2017, Journal of clinical and experimental neuropsychology.

[39]  O. Wolkowitz,et al.  Increased pro-inflammatory milieu in combat related PTSD – A new cohort replication study , 2017, Brain, Behavior, and Immunity.

[40]  N. Egorova,et al.  Early cortical biomarkers of longitudinal transcutaneous vagus nerve stimulation treatment success in depression , 2016, NeuroImage: Clinical.

[41]  Zengjian Wang,et al.  Transcutaneous vagus nerve stimulation modulates amygdala functional connectivity in patients with depression. , 2016, Journal of affective disorders.

[42]  S. Back,et al.  Posttraumatic Stress Disorder: Overview of Evidence-Based Assessment and Treatment , 2016, Journal of clinical medicine.

[43]  M. Nitsche,et al.  Safety of Transcranial Direct Current Stimulation: Evidence Based Update 2016 , 2016, Brain Stimulation.

[44]  G. Neigh,et al.  Co-morbidity of PTSD and immune system dysfunction: opportunities for treatment. , 2016, Current opinion in pharmacology.

[45]  Hong Meng,et al.  Effect of transcutaneous auricular vagus nerve stimulation on major depressive disorder: A nonrandomized controlled pilot study. , 2016, Journal of Affective Disorders.

[46]  R. Hauger,et al.  Noninvasive Transcutaneous Vagus Nerve Stimulation Decreases Whole Blood Culture‐Derived Cytokines and Chemokines: A Randomized, Blinded, Healthy Control Pilot Trial , 2016, Neuromodulation : journal of the International Neuromodulation Society.

[47]  Shih-Pin Chen,et al.  Vagus nerve stimulation inhibits cortical spreading depression , 2016, Pain.

[48]  Yang Wang,et al.  Transcutaneous Vagus Nerve Stimulation Modulates Default Mode Network in Major Depressive Disorder , 2016, Biological Psychiatry.

[49]  J. Bremner,et al.  Pharmacotherapy for PTSD: effects on PTSD symptoms and the brain , 2016 .

[50]  N. Wenderoth,et al.  A technical guide to tDCS, and related non-invasive brain stimulation tools , 2016, Clinical Neurophysiology.

[51]  Andrew H. Miller,et al.  The role of inflammation in depression: from evolutionary imperative to modern treatment target , 2015, Nature Reviews Immunology.

[52]  Ives Cavalcante Passos,et al.  Inflammatory markers in post-traumatic stress disorder: a systematic review, meta-analysis, and meta-regression. , 2015, The lancet. Psychiatry.

[53]  J. Ellrich,et al.  Non-invasive Access to the Vagus Nerve Central Projections via Electrical Stimulation of the External Ear: fMRI Evidence in Humans , 2015, Brain Stimulation.

[54]  A. Sack,et al.  Transcutaneous vagus nerve stimulation boosts associative memory in older individuals , 2015, Neurobiology of Aging.

[55]  J. Brunelin,et al.  Transcranial direct current stimulation in psychiatric disorders. , 2015, World journal of psychiatry.

[56]  S. Schachter,et al.  Vagus nerve stimulation reduces cardiac electrical instability assessed by quantitative T‐wave alternans analysis in patients with drug‐resistant focal epilepsy , 2014, Epilepsia.

[57]  John P. Greenwood,et al.  Non-invasive Vagus Nerve Stimulation in Healthy Humans Reduces Sympathetic Nerve Activity , 2014, Brain Stimulation.

[58]  Nicole M. Taylor,et al.  Proinflammatory milieu in combat-related PTSD is independent of depression and early life stress , 2014, Brain, Behavior, and Immunity.

[59]  S. Willett,et al.  Vagus nerve stimulation enhances extinction of conditioned fear and modulates plasticity in the pathway from the ventromedial prefrontal cortex to the amygdala , 2014, Front. Behav. Neurosci..

[60]  R. Raedt,et al.  Vagus nerve stimulation…25 years later! What do we know about the effects on cognition? , 2014, Neuroscience & Biobehavioral Reviews.

[61]  E. Olivier,et al.  Pupil size variations correlate with physical effort perception , 2014, Front. Behav. Neurosci..

[62]  Reese S. Terry,et al.  Vagus Nerve Stimulation Therapy for Epilepsy , 2014 .

[63]  Navid Khodaparast,et al.  The timing and amount of vagus nerve stimulation during rehabilitative training affect poststroke recovery of forelimb strength , 2014, Neuroreport.

[64]  M. Oshinsky,et al.  Noninvasive vagus nerve stimulation as treatment for trigeminal allodynia , 2014, PAIN®.

[65]  J. Ginsberg,et al.  Dysregulation in microRNA Expression Is Associated with Alterations in Immune Functions in Combat Veterans with Post-Traumatic Stress Disorder , 2014, PloS one.

[66]  R. Soufer,et al.  Psychological Stress and Induced Ischemic Syndromes , 2014, Current Cardiovascular Risk Reports.

[67]  Amit J. Shah,et al.  Posttraumatic Stress Disorder and Impaired Autonomic Modulation in Male Twins , 2013, Biological Psychiatry.

[68]  N. Engineer,et al.  Rapid Remission of Conditioned Fear Expression with Extinction Training Paired with Vagus Nerve Stimulation , 2013, Biological Psychiatry.

[69]  G. Debonnel,et al.  Electrophysiological and neurochemical effects of long-term vagus nerve stimulation on the rat monoaminergic systems. , 2013, The international journal of neuropsychopharmacology.

[70]  A. Rush,et al.  A patient-level meta-analysis of studies evaluating vagus nerve stimulation therapy for treatment-resistant depression , 2013, Medical devices.

[71]  A. Altamura,et al.  Vagus Nerve Stimulation in Treatment-Resistant Depression: Acute and Follow-Up Results of an Italian Case Series , 2013, The journal of ECT.

[72]  D. Dunner,et al.  Medicare patient experience with vagus nerve stimulation for treatment-resistant depression , 2013, Journal of medical economics.

[73]  Yuki Sugaya,et al.  Vagus nerve stimulation induced long-lasting enhancement of synaptic transmission and decreased granule cell discharge in the hippocampal dentate gyrus of urethane-anesthetized rats , 2013, Brain Research.

[74]  Jun-Cheng Guo,et al.  Study on serum cytokine levels in posttraumatic stress disorder patients. , 2012, Asian Pacific journal of tropical medicine.

[75]  A. Miller,et al.  The evolutionary significance of depression in Pathogen Host Defense (PATHOS-D) , 2012, Molecular Psychiatry.

[76]  E. Walker,et al.  Diagnostic and Statistical Manual of Mental Disorders , 2013 .

[77]  S. Smirnakis,et al.  Vagus nerve stimulation modulates cortical synchrony and excitability through the activation of muscarinic receptors , 2011, Neuroscience.

[78]  M. Krzyżaniak,et al.  Vagal Stimulation Modulates Inflammation through a Ghrelin Mediated Mechanism in Traumatic Brain Injury , 2011, Inflammation.

[79]  B. Olshansky,et al.  Inflammatory cytokines and nitric oxide in heart failure and potential modulation by vagus nerve stimulation , 2011, Heart Failure Reviews.

[80]  T. Jovanović,et al.  Repeated Assessments of Endocrine- and Immune-Related Changes in Posttraumatic Stress Disorder , 2011, Neuroimmunomodulation.

[81]  U. Das.  Can vagus nerve stimulation halt or ameliorate rheumatoid arthritis and lupus? , 2011, Lipids in Health and Disease.

[82]  D. Luckenbaugh,et al.  Sustained Elevation of Serum Interleukin-6 and Relative Insensitivity to Hydrocortisone Differentiates Posttraumatic Stress Disorder with and Without Depression , 2010, Biological Psychiatry.

[83]  S. Calvano,et al.  RELATIONSHIP OF BASAL HEART RATE VARIABILITY TO IN VIVO CYTOKINE RESPONSES after endotoxin exposure , 2010, Shock.

[84]  Albisua Sanchez Julio.  Vagus nerve stimulation for epilepsy , 2010, Drug and Therapeutics Bulletin.

[85]  B. Pfefferbaum,et al.  Emotional and biological stress measures in Katrina survivors relocated to Oklahoma. , 2010, American journal of disaster medicine.

[86]  Julian F. Thayer,et al.  Low vagal tone is associated with impaired post stress recovery of cardiovascular, endocrine, and immune markers , 2010, European Journal of Applied Physiology.

[87]  S. Calvano,et al.  RELATIONSHIP OFBASAL HEART RATE VARIABILITY TO IN VIVO CYTOKINE RESPONSES FOLLOWING ENDOTOXIN , 2009 .

[88]  H. Saner,et al.  Inflammatory Biomarkers in Patients with Posttraumatic Stress Disorder Caused by Myocardial Infarction and the Role of Depressive Symptoms , 2009, Neuroimmunomodulation.

[89]  R. Raedt,et al.  Effects of vagus nerve stimulation on pro- and anti-inflammatory cytokine induction in patients with refractory epilepsy , 2009, Journal of Neuroimmunology.

[90]  V. Vaccarino,et al.  Effects of a cognitive stress challenge on myocardial perfusion and plasma cortisol in coronary heart disease patients with depression. , 2009, Stress and health : journal of the International Society for the Investigation of Stress.

[91]  G. Debonnel,et al.  Enhancement of the function of rat serotonin and norepinephrine neurons by sustained vagus nerve stimulation. , 2009, Journal of psychiatry & neuroscience : JPN.

[92]  N. Simon,et al.  Broad spectrum of cytokine abnormalities in panic disorder and posttraumatic stress disorder , 2009, Depression and anxiety.

[93]  Charles L. Raison,et al.  Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression , 2009, Biological Psychiatry.

[94]  G. Debonnel,et al.  Optimization of vagus nerve stimulation parameters using the firing activity of serotonin neurons in the rat dorsal raphe , 2009, European Neuropsychopharmacology.

[95]  Meena Vythilingam,et al.  Low cortisol, high DHEA, and high levels of stimulated TNF-alpha, and IL-6 in women with PTSD. , 2008, Journal of traumatic stress.

[96]  Michael L. Levy,et al.  Vagus Nerve Stimulation , 2008, Proceedings of the IEEE.

[97]  Michele A. Schottenbauer,et al.  Nonresponse and Dropout Rates in Outcome Studies on PTSD: Review and Methodological Considerations , 2008, Psychiatry.

[98]  Sulagna Das,et al.  Inflammation: A new candidate in modulating adult neurogenesis , 2008, Journal of neuroscience research.

[99]  H. Sackeim,et al.  Durability of antidepressant response to vagus nerve stimulation (VNS). , 2007, The international journal of neuropsychopharmacology.

[100]  F. Marrosu,et al.  Vagus nerve stimulation increases norepinephrine concentration and the gene expression of BDNF and bFGF in the rat brain , 2007, Brain Research.

[101]  U. Schnyder,et al.  Evidence for low-grade systemic proinflammatory activity in patients with posttraumatic stress disorder. , 2007, Journal of psychiatric research.

[102]  S. Manuck,et al.  Stimulated Production of Proinflammatory Cytokines Covaries Inversely With Heart Rate Variability , 2007, Psychosomatic medicine.

[103]  J. Britton,et al.  Vagus nerve stimulation for epilepsy: is output current correlated with acute response? , 2007, Acta neurologica Scandinavica.

[104]  U. Das.  Vagus Nerve Stimulation, Depression, and Inflammation , 2007, Neuropsychopharmacology.

[105]  S. Targum,et al.  The clinical global impressions scale: applying a research tool in clinical practice. , 2007, Psychiatry (Edgmont (Pa. : Township)).

[106]  B. Rothbaum,et al.  Prolonged Exposure Therapy for PTSD : Emotional Processing of Traumatic Experiences Therapist Guide , 2007 .

[107]  P. Schnurr,et al.  Cognitive behavioral therapy for posttraumatic stress disorder in women: a randomized controlled trial. , 2007, JAMA.

[108]  Julian F. Thayer,et al.  The role of vagal function in the risk for cardiovascular disease and mortality , 2007, Biological Psychology.

[109]  Douglas C. Smith,et al.  Increased extracellular concentrations of norepinephrine in cortex and hippocampus following vagus nerve stimulation in the rat , 2006, Brain Research.

[110]  A. Dorr,et al.  Effect of Vagus Nerve Stimulation on Serotonergic and Noradrenergic Transmission , 2006, Journal of Pharmacology and Experimental Therapeutics.

[111]  Douglas C. Smith,et al.  Electrical stimulation of the vagus nerve enhances cognitive and motor recovery following moderate fluid percussion injury in the rat. , 2005, Journal of neurotrauma.

[112]  Mustafa M. Husain,et al.  Vagus Nerve Stimulation for Treatment-Resistant Depression: A Randomized, Controlled Acute Phase Trial , 2005, Biological Psychiatry.

[113]  Barry R. Rittberg,et al.  Effects of 12 Months of Vagus Nerve Stimulation in Treatment-Resistant Depression: A Naturalistic Study , 2005, Biological Psychiatry.

[114]  Barry R. Rittberg,et al.  A One-Year Comparison of Vagus Nerve Stimulation with Treatment as Usual for Treatment-Resistant Depression , 2005, Biological Psychiatry.

[115]  Jacquelyn C. Campbell,et al.  The Mediation Effect of Posttraumatic Stress Disorder Symptoms on the Relationship of Intimate Partner Violence and IFN-γ Levels , 2005, American journal of community psychology.

[116]  Cedric L. Williams,et al.  The effects of peripheral vagal nerve stimulation at a memory-modulating intensity on norepinephrine output in the basolateral amygdala. , 2004, Behavioral neuroscience.

[117]  D. Alexander,et al.  Disturbance of pro-inflammatory cytokines in post-traumatic psychopathology. , 2003, Cytokine.

[118]  E. Foa,et al.  Do Patients Drop Out Prematurely from Exposure Therapy for PTSD? , 2003, Journal of traumatic stress.

[119]  Kenneth J. Ruggiero,et al.  Psychometric Properties of the PTSD Checklist—Civilian Version , 2003, Journal of traumatic stress.

[120]  S. Southwick,et al.  Cortisol response to a cognitive stress challenge in posttraumatic stress disorder (PTSD) related to childhood abuse , 2003, Psychoneuroendocrinology.

[121]  I. Kerr,et al.  Cognitive analytic therapy , 2003, British Journal of Psychiatry.

[122]  H. Sackeim,et al.  Vagus nerve stimulation (VNS): utility in neuropsychiatric disorders. , 2003, The international journal of neuropsychopharmacology.

[123]  Markus Schwaninger,et al.  A mechanism converting psychosocial stress into mononuclear cell activation , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[124]  E. Ben-Menachem,et al.  Cognition-enhancing effect of vagus nerve stimulation in patients with Alzheimer's disease: a pilot study. , 2002, The Journal of clinical psychiatry.

[125]  H. Sackeim,et al.  Vagus nerve stimulation (VNS) for major depressive episodes: one year outcomes , 2002, Biological Psychiatry.

[126]  George P. Chrousos,et al.  Plasma and Cerebrospinal Fluid Interleukin-6 Concentrations in Posttraumatic Stress Disorder , 2002, Neuroimmunomodulation.

[127]  Cole A. Giller,et al.  Vagus Nerve Stimulation (VNS™) for Treatment-Resistant Depression: Efficacy, Side Effects, and Predictors of Outcome , 2001, Neuropsychopharmacology.

[128]  P. Keck,et al.  CSF norepinephrine concentrations in posttraumatic stress disorder. , 2001, The American journal of psychiatry.

[129]  A. Grace,et al.  Chronic cold exposure potentiates CRH-evoked increases in electrophysiologic activity of locus coeruleus neurons , 2001, Biological Psychiatry.

[130]  R. Miller,et al.  C-reactive protein and interleukin 6 receptor in post-traumatic stress disorder: a pilot study. , 2001, Cytokine.

[131]  W. Roth,et al.  Psychophysiological assessment: clinical applications for PTSD. , 2000, Journal of affective disorders.

[132]  M Tanaka,et al.  Noradrenaline systems in the hypothalamus, amygdala and locus coeruleus are involved in the provocation of anxiety: basic studies. , 2000, European journal of pharmacology.

[133]  K. Tracey,et al.  Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin , 2000, Nature.

[134]  Mustafa M. Husain,et al.  Vagus nerve stimulation: a new tool for brain research and therapy∗ , 2000, Biological Psychiatry.

[135]  Robert Goodman,et al.  Vagus nerve stimulation (VNS) for treatment-resistant depressions: a multicenter study∗ ∗ See accompanying Editorial, in this issue. , 2000, Biological Psychiatry.

[136]  S. Southwick,et al.  Neural correlates of memories of childhood sexual abuse in women with and without posttraumatic stress disorder. , 1999, The American journal of psychiatry.

[137]  T. Pigott,et al.  Gender differences in the epidemiology and treatment of anxiety disorders. , 1999, The Journal of clinical psychiatry.

[138]  Matcheri S Keshavan,et al.  Developmental traumatology part I: biological stress systems∗ ∗ See accompanying Editorial, in this issue. , 1999, Biological Psychiatry.

[139]  Suzanne Witterholt,et al.  Treating the Trauma of Rape: Cognitive-Behavioral Therapy for PTSD , 1999 .

[140]  E. Ben-Menachem,et al.  Evaluation of refractory epilepsy treated with vagus nerve stimulation for up to 5 years , 1999, Neurology.

[141]  S. Orr,et al.  Psychophysiologic assessment of women with posttraumatic stress disorder resulting from childhood sexual abuse. , 1998, Journal of consulting and clinical psychology.

[142]  B. Uthman,et al.  Vagus nerve stimulation therapy for partial-onset seizures , 1998, Neurology.

[143]  S. Krahl,et al.  Locus Coeruleus Lesions Suppress the Seizure‐Attenuating Effects of Vagus Nerve Stimulation , 1998, Epilepsia.

[144]  Martin H. Teicher,et al.  Plasma norepinephrine and 3-methoxy-4-hydroxyphenylglycol concentrations and severity of depression in combat posttraumatic stress disorder and major depressive disorder , 1998, Biological Psychiatry.

[145]  S. Orr,et al.  A prospective study of heart rate response following trauma and the subsequent development of posttraumatic stress disorder. , 1998, Archives of general psychiatry.

[146]  C. A. Morgan,et al.  Noradrenergic and serotonergic function in posttraumatic stress disorder. , 1997, Archives of general psychiatry.

[147]  L H Staib,et al.  Positron emission tomography measurement of cerebral metabolic correlates of yohimbine administration in combat-related posttraumatic stress disorder. , 1997, Archives of general psychiatry.

[148]  Basim M. Uthman,et al.  Vagus Nerve Stimulation for the Treatment of Medically Intractable Seizures: Results of a 1-Year Open-Extension Trial , 1996 .

[149]  S. Southwick,et al.  Noradrenergic mechanisms in stress and anxiety: I. preclinical studies , 1996, Synapse.

[150]  S. Southwick,et al.  Chronic PTSD in Vietnam combat veterans: course of illness and substance abuse. , 1996, The American journal of psychiatry.

[151]  C. Coe,et al.  Abuse-Related Posttraumatic Stress Disorder: Evidence for Chronic Neuroendocrine Activation in Women , 1995, Psychosomatic medicine.

[152]  Lippincott Williams Wilkins,et al.  A randomized controlled trial of chronic vagus nerve stimulation for treatment of medically intractable seizures , 1995, Neurology.

[153]  M. J. Zigmond,et al.  Increased dopamine and norepinephrine release in medial prefrontal cortex induced by acute and chronic stress: Effects of diazepam , 1995, Neuroscience.

[154]  S. Orr,et al.  Physiologic responses to loud tones in Vietnam veterans with posttraumatic stress disorder. , 1995, Journal of abnormal psychology.

[155]  E. Ben-Menachem,et al.  Vagus Nerve Stimulation for Treatment of Partial Seizures: 1. A Controlled Study of Effect on Seizures , 1994, Epilepsia.

[156]  R. Kuzniecky,et al.  Vagus Nerve Stimulation for Treatment of Partial Seizures: 3. Long‐Term Follow‐Up on First 67 Patients Exiting a Controlled Study , 1994, Epilepsia.

[157]  M. D. De Bellis,et al.  Urinary catecholamine excretion in sexually abused girls. , 1994, Journal of the American Academy of Child and Adolescent Psychiatry.

[158]  F. Petty,et al.  Learned helplessness and in vivo hippocampal norepinephrine release , 1993, Pharmacology Biochemistry and Behavior.

[159]  E. Abercrombie,et al.  Presynaptic alterations associated with enhancement of evoked release and synthesis of norepinephrine in hippocampus of chronically cold-stressed rats , 1993, Brain Research.

[160]  C. A. Morgan,et al.  Abnormal noradrenergic function in posttraumatic stress disorder. , 1993, Archives of general psychiatry.

[161]  S. Orr,et al.  Psychophysiological assessment of posttraumatic stress disorder imagery in World War II and Korean combat veterans. , 1993, Journal of abnormal psychology.

[162]  A. Hamberger,et al.  Neurochemical effects of vagus nerve stimulation in humans , 1992, Brain Research.

[163]  R. Veith,et al.  Basal sympathoadrenal function in posttraumatic distress disorder , 1992, Biological Psychiatry.

[164]  E. Blanchard,et al.  Changes in Plasma Norepinephrine to Combat‐Related Stimuli among Vietnam Veterans with Posttraumatic Stress Disorder , 1991, The Journal of nervous and mental disease.

[165]  M. Zigmond,et al.  Prior exposure to chronic stress results in enhanced synthesis and release of hippocampal norepinephrine in response to a novel stressor , 1991, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[166]  B. Jacobs,et al.  Activity of cat locus coeruleus noradrenergic neurons during the defense reaction , 1990, Brain Research.

[167]  Miles E. McFall,et al.  Autonomic responses to stress in Vietnam combat veterans with posttraumatic stress disorder , 1990, Biological Psychiatry.

[168]  P. Leung,et al.  Clonidine in Cambodian Patients with Posttraumatic Stress Disorder , 1989, The Journal of nervous and mental disease.

[169]  J. Rosell,et al.  Skin impedance from 1 Hz to 1 MHz , 1988, IEEE Transactions on Biomedical Engineering.

[170]  E. Giller,et al.  Elevation of Urinary Norepinephrine/Cortisol Ratio in Posttraumatic Stress Disorder , 1988, The Journal of nervous and mental disease.

[171]  B. Jacobs,et al.  Single-unit response of noradrenergic neurons in the locus coeruleus of freely moving cats. I. Acutely presented stressful and nonstressful stimuli , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[172]  B. Jacobs,et al.  Single-unit response of noradrenergic neurons in the locus coeruleus of freely moving cats. II. Adaptation to chronically presented stressful stimuli , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[173]  E. Blanchard,et al.  Cardiac response to relevant stimuli as an adjunctive tool for diagnosing post-traumatic stress disorder in Vietnam veterans * , 1986 .

[174]  M. Turiel,et al.  Power Spectral Analysis of Heart Rate and Arterial Pressure Variabilities as a Marker of Sympatho‐Vagal Interaction in Man and Conscious Dog , 1986, Circulation research.

[175]  R. Kvetňanský,et al.  Effect of repeated immobilization stress on central and peripheral adrenoceptors in rats. , 1985, Endocrinologia experimentalis.

[176]  J. D. McGaugh.  Peripheral and Central Adrenergic Influences on Brain Systems Involved in the Modulation of Memory Storage a , 1985, Annals of the New York Academy of Sciences.

[177]  J. Fairbank,et al.  Validation of a multimethod assessment of posttraumatic stress disorders in Vietnam veterans. , 1983, Journal of consulting and clinical psychology.

[178]  F. Bloom,et al.  Nucleus locus ceruleus: new evidence of anatomical and physiological specificity. , 1983, Physiological reviews.

[179]  J. Weiss,et al.  Behavioral depression produced by an uncontrollable stressor: Relationship to norepinephrine, dopamine, and serotonin levels in various regions of rat brain , 1981, Brain Research Reviews.

[180]  D E Redmond,et al.  Current concepts. II. New evidence for a locus coeruleus-norepinephrine connection with anxiety. , 1979, Life sciences.

[181]  M. Hamilton.  A RATING SCALE FOR DEPRESSION , 1960, Journal of neurology, neurosurgery, and psychiatry.

[182]  M. Hamilton.  The assessment of anxiety states by rating. , 1959, The British journal of medical psychology.

[183]  Omer T Inan,et al.  Timing Considerations for Noninvasive Vagal Nerve Stimulation in Clinical Studies , 2019, AMIA.

[184]  P. Schnurr,et al.  Cognitive Behavioral Therapy for Posttraumatic Stress Disorder in Women , 2017 .

[185]  M. Bikson,et al.  What Psychiatrists Need to Know About Transcranial Direct Current Stimulation , 2017 .

[186]  C. Wilder-Smith,et al.  Combat-training stress in soldiers increases S100B, a marker of increased blood-brain-barrier permeability, and induces immune activation. , 2014, Neuro endocrinology letters.

[187]  Treatment for posttraumatic stress disorder in military and veteran populations: final assessment. , 2014, Military medicine.

[188]  M. Kilgard,et al.  Targeting plasticity with vagus nerve stimulation to treat neurological disease. , 2013, Progress in brain research.

[189]  A. Grace,et al.  Chronic Stress Increases the Plasmalemmal Distribution of the Norepinephrine Transporter and the Coexpression of Tyrosine Hydroxylase in Norepinephrine Axons in the Prefrontal Cortex , 2006, The Journal of Neuroscience.

[190]  E. Blanchard,et al.  A psychophysiological study of Post Traumatic Stress Disorder in Vietnam veterans , 2005, Psychiatric Quarterly.

[191]  D. Nutt,et al.  Consensus statement update on posttraumatic stress disorder from the international consensus group on depression and anxiety. , 2004, The Journal of clinical psychiatry.

[192]  M. First,et al.  The Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I) and the Structured Clinical Interview for DSM-IV Axis II Disorders (SCID-II). , 2004 .

[193]  H. Sackeim,et al.  The effects of vagus nerve stimulation on cognitive performance in patients with treatment-resistant depression. , 2001, Neuropsychiatry, neuropsychology, and behavioral neurology.

[194]  D J Nutt,et al.  Consensus statement on posttraumatic stress disorder from the International Consensus Group on Depression and Anxiety. , 2000, The Journal of clinical psychiatry.

[195]  Allen Frances,et al.  The expert consensus guideline series. Treatment of Posttraumatic Stress Disorder. The Expert Consensus Panels for PTSD. , 1999, The Journal of clinical psychiatry.

[196]  Dean K. Naritoku,et al.  Enhanced recognition memory following vagus nerve stimulation in human subjects , 1999, Nature Neuroscience.

[197]  M. Keshavan,et al.  A.E. Bennett Research Award. Developmental traumatology. Part I: Biological stress systems. , 1999, Biological psychiatry.

[198]  B. Uthman,et al.  Vagus nerve stimulation for the treatment of medically intractable seizures. Results of a 1-year open-extension trial. Vagus Nerve Stimulation Study Group. , 1996, Archives of neurology.

[199]  S. Southwick,et al.  Noradrenergic mechanisms in stress and anxiety: II. Clinical studies. , 1996, Synapse.

[200]  D. Charney,et al.  The development of a Clinician-Administered PTSD Scale , 1995, Journal of traumatic stress.

[201]  G Chouvet,et al.  Afferent regulation of locus coeruleus neurons: anatomy, physiology and pharmacology. , 1991, Progress in brain research.

[202]  I. Heuser,et al.  The Hamilton Anxiety Scale: reliability, validity and sensitivity to change in anxiety and depressive disorders. , 1988, Journal of affective disorders.