An analog front-end for the acquisition of biomedical signals, fully integrated in a 0.8 /spl mu/m CMOS process

This work explores the feasibility of a cardiac pacemaker front-end, realized using a fully integrated solution. Particularly two different architectures for the sensing chain are compared. The first is based on an SC biquadratic cell and performs the minimum signal processing required, i.e. a band-pass filtering before peak detection. The second is based on a /spl Sigma//spl Delta/ converter, allowing for more advanced pacing strategies. Both architectures require a low-noise pre-amplifier, realized as a log-domain filter, and pose typical challenges of low-voltage and low-power design. Both circuits, realized in 0.8 /spl mu/m CMOS process, behave as required by the application and have a reduced power consumption. Hence the feasibility of fully-integrated solution is proved, for both sensing approaches, giving the possibility to drastically reduce pacemaker size.

[1]  D. R. Frey Current mode class AB second order filter , 1994 .

[2]  R. Castello,et al.  A 1 V 1.8 MHz CMOS switched-opamp SC filter with rail-to-rail output swing , 1997, 1997 IEEE International Solids-State Circuits Conference. Digest of Technical Papers.

[3]  W. Sansen,et al.  A 1.5-V-100-/spl mu/W /spl Delta//spl Sigma/ modulator with 12-b dynamic range using the switched-opamp technique , 1997 .

[4]  Andrea Baschirotto,et al.  Low-voltage analog filters , 1995 .

[5]  Andrea Gerosa,et al.  A micro-power low noise log-domain amplifier for the sensing chain of a cardiac pacemaker , 2001, ISCAS 2001. The 2001 IEEE International Symposium on Circuits and Systems (Cat. No.01CH37196).

[6]  E. Seevinck,et al.  Companding current-mode integrator: A new circuit principle for continuous-time monolithic filters , 1990 .

[7]  C. C. Enz,et al.  A 1.2-V low-power BiCMOS class AB log-domain filter , 1997, IEEE J. Solid State Circuits.

[8]  Andrea Gerosa,et al.  Low-power sensing and digitization of cardiac signals based on sigma-delta conversion , 2000, ISLPED'00: Proceedings of the 2000 International Symposium on Low Power Electronics and Design (Cat. No.00TH8514).